Rapid Identification of Superior Endogenous Signal Peptides for Heterologous Protein Secretion by Corynebacterium glutamicum Through Modular Cloning and Automation [0.03%]
通过模块化克隆和自动化快速识别优异内源信号肽以实现谷氨酸棒杆菌异源蛋白分泌
Susana Matamouros,Julia Tenhaef,Astrid Bida et al.
Susana Matamouros et al.
Secretory protein production by microbial hosts simplifies product recovery and is therefore preferred over intracellular production. Efficient secretion of heterologous proteins by bacteria requires the identification of optimal signal pep...
Phylogeny-Aware Metabologenomics Accurately Assigns Natural Products to Biosynthetic Gene Clusters [0.03%]
谱系 aware 的元代谢基因组学准确地将天然产物分配给生物合成基因簇
Judith Boldt,Christoph Porten,F P Jake Haeckl et al.
Judith Boldt et al.
Tens of thousands of biosynthetic gene clusters (BGCs) have been identified in microbial genomes, but the vast majority of associated natural products (NPs) and their underlying biosyntheses remain unknown. Metabologenomics approaches integ...
Plant Immunity-Activating Endophytic Bacteria Induce Dynamic Metabolic Changes in Cultured Plant Cells Without Inhibiting Their Growth [0.03%]
诱导植物细胞代谢动态变化的内生细菌在其不抑制生长的情况下激活植物免疫力
Yui Aikawa,Ayano Yabuuchi,Hiroki Kaneko et al.
Yui Aikawa et al.
Co-culture of microorganisms with plant cells is a promising approach for inducing gene expression for the synthesis of bioactive compounds in cultured plant cells. However, the use of microorganisms is often difficult because they tend to ...
Characterisation of a Novel Jumbo Lytic Aeromonas dhakensis Bacteriophage P19 and Its Endolysin [0.03%]
新型芽孢杆菌大噬菌体P19及其内溶酶的表征
Farhat Ansari,Vandan Nagar
Farhat Ansari
Aeromonas dhakensis is an emerging multidrug-resistant (MDR) bacterial pathogen that presents significant threats to public health and aquaculture. This study reports the isolation and comprehensive characterisation of jumbo bacteriophage P...
Cyanobacterial Extracellular Vesicles as Protein Carriers: Towards Fish Vaccination [0.03%]
蓝藻细胞外囊泡作为蛋白递送载体在鱼类疫苗中的应用研究
Jorge Matinha-Cardoso,Gabriela Gonçalves,Filipe Coutinho et al.
Jorge Matinha-Cardoso et al.
Fish aquaculture faces significant economic losses from disease outbreaks. Vaccination is the most effective prevention strategy, and bacterial extracellular vesicles (EVs) show promise as vaccine platforms due to their strong immuno-stimul...
Betulinic Acid Eradicates Implant-Associated Infections by Disrupting the S. aureus Biofilm Matrix and Potentiating Host Immune Clearance [0.03%]
betulinic酸通过破坏S. aureu的生物膜基质并增强宿主免疫清除来根除与植入物相关的感染
Dongbin Guo,Ye Tao,Luanbiao Sun et al.
Dongbin Guo et al.
Staphylococcus aureus biofilms are major contributors to chronic and recurrent infections due to their intrinsic tolerance to antibiotics and host immune clearance, highlighting the urgent need for safe and effective antibiofilm strategies....
Correction to "Combination of an Engineered Lactococcus lactis Expressing CXCL12 With Light-Emitting Diode Yellow Light as a Treatment for Scalded Skin in Mice" [0.03%]
“关于工程改造的乳酸菌表达CXCL12与LED黄光联合治疗小鼠烧伤的研究”的更正通知
Published Erratum
Microbial biotechnology. 2026 Jan;19(1):e70296. DOI:10.1111/1751-7915.70296 2026
Microbial Community Restructuring Enhances Composting Efficiency: Synergistic Roles of Thermal Cycling and Fungal Inoculants (Fomes lignosus and Penicillium glabrum) in Metabolic Adaptation [0.03%]
微生物群落重构提高堆肥效率：热循环和真菌接种（Varroa destructor和Penicillium glabrum）在代谢适应中的协同作用
Yukun Chen,Xiaofang Gong,Xiaobin Xiong et al.
Yukun Chen et al.
This study demonstrates that synergistic integration of thermal cycling (28°C-58°C) and fungal inoculants (Fomes lignosus, Penicillium glabrum) enhances humification in cattle manure composting by restructuring microbial communities towar...
A Modified Method Incorporating Multiplex PCR Reveals Fusobacterium Prevalence in Southern Chinese Population and Its Correlations in Cancers [0.03%]
一种改良的多重PCR方法揭示了口腔幽门螺杆菌在中国南方人群中的流行情况及其与癌症的关系
Tingting Shen,Jiarui Liang,Xuyu Li et al.
Tingting Shen et al.
Fusobacterium, a gram-negative anaerobic bacillus in mouth, gastrointestinal tract and elsewhere, has long been considered as opportunistic pathogen. Increasing evidence indicate the association of Fusobacterium with human diseases, especia...
Engineering an AlkS-PalkB Transcription Factor-Based Biosensor With Improved Sensitivity to Isobutanol and Other Short-Chain Alcohols [0.03%]
工程构建高灵敏度识别异丁醇等低碳链醇类化合物的AlkS-PalkB型转录因子生物传感器
Jiaming Chen,Xizi Wang,Can Zhu et al.
Jiaming Chen et al.
Isobutanol, a promising biofuel with higher energy content than ethanol, presents a sustainable alternative through biosynthesis. However, enhancing yield remains challenging due to the inefficiencies in microbial synthesis. This study intr...