A general analytic approach to predicting the best antibiotic dosing regimen [0.03%]
预测最佳抗生素用药方案的通用解析方法
Leah Childers,Pia Abel Zur Wiesch,Jessica M Conway
Leah Childers
Determining optimal antibiotic dosing strategies is complex. Clinically, some antibiotics work best in continuous low doses, while others require high repeated pulses. However, a rational understanding of the best approach depending on the ...
Cuicui Jiang,Yanni Tian,Miaoran Yao et al.
Cuicui Jiang et al.
To study the macroscopic dynamics of susceptible host cells, infected host cells, free virus particles and antibodies after viral infection within-host, this study develops a novel dynamic model that integrates three key mechanisms: a gener...
Nolbert Morales,Edward A Turner,Jorge L Zapata
Nolbert Morales
We study periodic dynamics and error-threshold behavior in a delayed quasispecies model consisting of a master sequence (x0) and two mutant populations (x1,x2). The system, formulated as delay differential equations with time-periodic repli...
The dynamics of hepatitis B virus transmission using a stochastic differential model and feed forward neural network approach [0.03%]
基于随机微分模型和前馈神经网络方法的乙型肝炎病毒传播动力学研究
Tahir Khan,Muhammad Asif,Muhammad Said et al.
Tahir Khan et al.
Hepatitis B transmission is influenced by environmental variability, immune response and vaccination, making its spread inherently stochastic, while the integration of stochastic modeling with machine learning is particularly important for ...
Stability and bifurcation analysis of a discrete plankton system with holling Type-II predation and toxin effects [0.03%]
具Holling II型功能反应和毒素效应的离散浮游生物系统的稳定性与分歧分析
Abdou Al Zubaidi,Muhammad Rafaqat,Jihad Younis et al.
Abdou Al Zubaidi et al.
This work examines the dynamics of a discrete-time plankton interaction model, in which phytoplankton generate toxins and are vulnerable to external contamination. The model includes a Holling Type-II predation response and uses a piecewise...
Modelling and analyzing the transmission dynamics of HIV/AIDS epidemic in China [0.03%]
中国艾滋病流行的传播动力学模拟及分析模型
Lili Su,Weide Li,Yumei Ma
Lili Su
Based on the considerations of round-trip in the treatment process, this paper presents a mathematical model aimed at studying the dynamic behaviour and epidemiological trends of HIV/AIDS. We first calculate the basic reproduction number R&...
Impact of starvation-driven diffusions and diverse interspecific competitions on species coexistence and fitness [0.03%]
饥饿驱动的扩散和多样化的种间竞争对物种共存与适应性的影响
Youngseok Chang,Inkyung Ahn,Wonhyung Choi
Youngseok Chang
This study examines competition models based on the Lotka-Volterra form that incorporate starvation-driven diffusions (SDD). Such dispersal assumes that species disperse in response to resource abundance or scarcity in a heterogeneous habit...
Dynamical analysis of an age-structured COVID-19 transmission model with voluntary vaccination strategies and evolutionary game [0.03%]
具有自愿接种策略和进化博弈的年龄结构COVID-19传播模型的动力学分析
Qingxia Ma,Jie Xu,Gang Huang
Qingxia Ma
COVID-19 infection exhibits significant age-related differences. In this paper, we consider an infectious disease model with age-structure in susceptibility and evolutionary game and analyze the impact of mandatory and voluntary vaccination...
Insights into mathematical model with efficient control measures for lumpy skin disease of cattle considering the presence of contaminated environment [0.03%]
考虑环境污染的牛肤芽病数学模型的有效控制措施研究
Faizah J Alanazi,Hegagi M Ali,Essam M Elsaid et al.
Faizah J Alanazi et al.
In this paper, we introduce a mathematical simulation that captures the dynamics of lumpy skin disease (LSD) by considering three key transmission paths: vector-borne, direct cattle-to-cattle contact and environmental contamination. Additio...
Dynamics of a diffusive HTLV and HIV coinfection model with macrophages, latent cells and two delays [0.03%]
带有巨噬细胞、潜伏细胞和两种时滞的扩散性人类T淋巴细胞病毒和人类免疫缺陷病毒感染模型的动力学性质研究
Hui Miao,Xiaomei Feng
Hui Miao
Human T-lymphotropic virus (HTLV) and human immunodeficiency virus (HIV) are two retroviruses that pose a certain threat to human psychology and physiology. In this paper, we propose a diffusive HTLV and HIV coinfection model with macrophag...