Beyond migraine: CGRP inhibition at the neurovascular interface and its implications for glaucoma risk [0.03%]
超越偏头痛：神经血管界面的CGRP抑制及其对青光眼风险的影响
Chien-Chih Chou,Taemin Kim,Ssu-Yu Pan et al.
Chien-Chih Chou et al.
Trimethoprim-sulfamethoxazole associated respiratory failure: a rapid review of the literature [0.03%]
关于肺孢子菌肺炎相关呼吸衰竭的文献快速回顾：甲氧苄啶-磺胺甲恶唑与之相关的呼吸衰竭
Nina Butkovich,Keri Swaggart,Jenna O Miller et al.
Nina Butkovich et al.
Introduction: Trimethoprim-sulfamethoxazole (TMP-SMX) is a widely used and generally well tolerated antibiotic. Its association with life-threatening respiratory failure was described in a 2019 case series showing high ra...
Why do bisphosphonates work in the treatment of CRPS? A translational pharmacological perspective to solve a conundrum [0.03%]
双膦酸盐为何能用于CRPS的治疗？一种转化药理学观点或可解释这一悖论
Massimo Varenna,Chiara Crotti,Raffaele Di Taranto et al.
Massimo Varenna et al.
Introduction: Bisphosphonates (BPs) have consistently yielded positive results in the treatment of Complex Regional Pain Syndrome (CRPS). However, biochemical and histopathological evidence suggests that osteoclasts, the ...
Profiling the pattern of medication use during pregnancy: an international scoping review of observational studies [0.03%]
一项国际观察性研究的系统评价：妊娠期间用药模式的剖绘分析
Irin Parvin,Hanan Abunimeh,Hisham Alshammari et al.
Irin Parvin et al.
Introduction: Medication use during pregnancy has increased significantly worldwide. However, detailed evidence on prescribing patterns during pregnancy remains limited. This scoping review aimed to summarize and provide ...
Could GLP-1RAs improve outcomes for patients with chronic migraine? [0.03%]
GLP-1受体激动剂能改善慢性偏头痛患者的预后吗？
Tsung-Wei Hou,Vitoria Acar,Hsiangkuo Yuan
Tsung-Wei Hou
Obese and overweight patients with type 2 diabetes mellitus are not treated optimally - an overview of current clinical practice and future perspectives [0.03%]
肥胖或超重的2型糖尿病患者未得到最优化治疗-目前临床实践和未来展望概览
Tanja Miličević Milardović,Ivna Cvitković,Špela Volčanšek et al.
Tanja Miličević Milardović et al.
Introduction: Type 2 diabetes mellitus (T2DM) pharmacotherapy guidelines recommend the assessment of individual cardiovascular (CV) risk. However, obesity still seems of lesser importance in the context of CV risk. Import...
Improving evidence-based antiseizure medication prescribing during pregnancy: strengthening research and clinical practice [0.03%]
改善妊娠期间基于证据的抗癫痫药物处方：加强研究和临床实践
Adrienne Y L Chan,Ian C K Wong,Kenneth K C Man
Adrienne Y L Chan
Brexpiprazole for anxiety symptoms in people living with schizophrenia: a plain language summary [0.03%]
关于布 Rexiapral 治疗精神分裂症患者的焦虑症状的简易版总结
Anja Farovik,Murat Yildirim,Shivani Kapadia et al.
Anja Farovik et al.
The systems medicine view of semaglutide: from clinical trials to molecular mechanisms [0.03%]
司美格鲁肽的系统医学观点：从临床试验到分子机制
Rui Vitorino
Rui Vitorino
Introduction: Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), is a key therapy in managing type 2 diabetes (T2D), offering significant improvements in glycemic control, weight loss, and cardiovascular p...
Beyond snapshot dosing: a dynamic living digital twin framework for model-informed precision dosing in critical illness [0.03%]
超越快照剂量法：危重病精准给药的动态数字孪生框架
Hulya Tezel Yalcin,Nadir Yalçın
Hulya Tezel Yalcin
Introduction: Model-Informed Precision Dosing (MIPD) has improved individualized therapy, but in critical illness its reliance on intermittently updated data creates a temporal mismatch between pharmacokinetic (PK) models...