Single-cell transcriptomics and machine learning unveil liquid-liquid phase separation-related biomarkers in HPV-positive cervical cancer [0.03%]
单细胞转录组和机器学习揭示HPV阳性的宫颈癌液-液相分离相关生物标志物
Yiru Chen
Yiru Chen
Background: Liquid-liquid phase separation (LLPS) dysregulation is a key driver of oncogenesis, yet its specific role in HPV-positive cervical cancer remains undefined. We hypothesized that HPV-positive tumors exploit dis...
High-risk human papillomavirus positivity and associated factors among women living with HIV in public health facilities of Mekelle, Northern Ethiopia [0.03%]
埃塞俄比亚默克莱市公立医院HIV感染妇女的高危人乳头瘤病毒阳性率及影响因素调查
Mebrahtu Teweldemedhin Shfare,Hayelom Kahsay,Gebrecherkos Teame Gebrehiwot et al.
Mebrahtu Teweldemedhin Shfare et al.
Background: Worldwide, it is believed that high-risk human papillomavirus (hr-HPV) strains are the root cause of many types of cancers, including cervical cancer, anorectal cancers, vaginal cancers, and penile cancers, wi...
Molecular characterization of HPV integrations in high-risk HPV-positive women and development of a prognostic signature based on integration-associated genes for cervical cancer [0.03%]
高危HPV阳性女性中宫颈癌相关HPV整合位点的分子特征及基于整合基因的预后标志物研究
Qiongying Lyu,Jiahui Zhao,Yurou Chen et al.
Qiongying Lyu et al.
Background: HPV integration into the human genome is a key molecular event in the progression of cervical cancer carcinogenesis. Methods: ...
Role of gut microbiota in cancer modulation: molecular mechanisms and emerging therapeutic strategies [0.03%]
肠道菌群在癌症调控中的作用：分子机制和新兴治疗策略
Subham Preetam,Jutishna Bora,Sthiti Porna Dutta et al.
Subham Preetam et al.
The gut microbiota exerts profound effects on host physiology, immunity, and disease susceptibility, with growing evidence implicating its role in cancer initiation, progression, and therapy response. Dysbiosis and microbial-derived metabol...
Kalipa Gedion,Elizabeth R Blackwood,Judith Mwobobia et al.
Kalipa Gedion et al.
Background: People living with HIV (PLHIV) are at an increased risk of oral manifestations, including those linked to human papillomavirus (HPV). In Tanzania, the prevalence and impact of oral HPV among PLHIV remain unkno...
Absence of chlamydial infection in ocular adnexal MALT lymphoma based on next-generation sequencing [0.03%]
基于下一代测序技术未在眼附属器MALT淋巴瘤中发现沙眼衣原体感染
Yoshihiro Yakushijin,Kazuhiro Horiba,Masanori Hashino et al.
Yoshihiro Yakushijin et al.
Objectives: Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) arises in various extranodal sites and has been linked to chronic inflammation, often triggered by infectious agents. Ocular adnexa...
Genomic and transcriptomic differences between neuroendocrine neoplasms and carcinomas with human papillomavirus (HPV) [0.03%]
人乳头瘤病毒（HPV）相关神经内分泌肿瘤和癌的基因组和转录组差异
Morgann Madill,Udhayvir Grewal,Harris Krause et al.
Morgann Madill et al.
Introduction: Human papillomavirus (HPV) is a well-established oncogenic virus implicated in the development of several epithelial cancers, most notably cervical, anogenital, and oropharyngeal carcinomas. In contrast, neu...
Regulation of immune tolerance in hepatocellular carcinoma by liver diseases: a review [0.03%]
肝脏疾病介导的肝细胞癌免疫耐受调节机制研究进展
Jinyi Li,Yuanda Liu
Jinyi Li
Paired box 1 gene methylation as a promising triage strategy for atypical squamous cells: a retrospective comparison with high-risk HPV testing in cervical cancer screening [0.03%]
POU类转录因子2A基因甲基化用于宫颈细胞学检查异常鳞状上皮内病变的分流筛查价值：与高危型HPV检测比较的回顾性研究
Hong Tao,Zhengjiao Tong,Hongtao Li et al.
Hong Tao et al.
Background: The triage of Atypical Squamous Cells (ASC) is pivotal in cervical cancer (CC) screening. This study aimed to evaluate the performance of paired box 1 gene methylation (PAX1m) testing for triaging cervical int...
Penile HPV prevalence among high-risk men in Sri Lanka: baseline insight for HPV prevention strategies in a lower-middle-income country [0.03%]
斯里兰卡高危男性中阴茎HPV感染率：低收入国家中HPV预防策略的初步见解
W D J K Amarasena,Sampatha Goonewardena,Deepa Gamage
W D J K Amarasena