The quantitative profiling of blood mSEPT9 determines the detection performance on colorectal tumors [0.03%]
血液mSEPT9的定量检测谱图决定了其检测结直肠肿瘤的表现性能
Lele Song,Jiayu Wang,Huaiqing Wang et al.
Lele Song et al.
Aim: To investigate the quantitative relationship between the positive detection rate (PDR) in colorectal tumor detection and the mSEPT9 level. Materials ...
Comprehensive analysis of miRNA-mRNA-lncRNA networks in severe asthma [0.03%]
严重哮喘中miRNA-mRNA-lncRNA网络的综合分析
Yi Chen,Zheng-Dao Mao,Yu-Jia Shi et al.
Yi Chen et al.
Aim: This study aimed to explore the molecular mechanism of severe asthma. Materials & methods: The shared and divergent differentially...
DNA hydroxymethylation changes in response to spinal cord damage in a multiple sclerosis mouse model [0.03%]
小鼠多发性硬化模型中脊髓损伤后DNA羟甲基化的改变
Yan Tang,Man Luo,Kailing Pan et al.
Yan Tang et al.
Aim: Roles of DNA 5-hydroxymethylcytosine (5hmC) in myelin repair were investigated in an experimental autoimmune encephalomyelitis (EAE) mouse model via its regulation on BDNF. ...
DNA methylation profiling as a tool for testicular germ cell tumors subtyping [0.03%]
DNA甲基化谱作为睾丸生殖细胞瘤分型的工具
Ana L Costa,Catarina Moreira-Barbosa,João Lobo et al.
Ana L Costa et al.
Aim: Assess differential patterns of selected five genes' promoter methylation among testicular germ cell tumors (TGCT) subtypes. Materials & methods: ...
Identification and integrated analysis of key differentially expressed circular RNAs in ER-positive subtype breast cancer [0.03%]
识别并综合分析ER阳性亚型乳腺癌中关键差异表达的环形RNA
Chenwei Yuan,Liheng Zhou,Lei Zhang et al.
Chenwei Yuan et al.
Aim: To systematically profile and characterize the circular RNA (circRNA) expression pattern in estrogen receptor (ER)-positive breast cancer (BC). Mater...
Genome-wide epigenetic landscape of pig lincRNAs and their evolution during porcine domestication [0.03%]
猪长链非编码RNA的表观遗传景观及其在驯化过程中的演化规律
Cencen Li,Cheng Zou,Yong Cui et al.
Cencen Li et al.
Aim: We aimed to identify previously unreported long intergenic noncoding RNAs (lincRNAs) in the porcine liver, an important metabolic tissue, and further illustrate the epigenomic landscapes and the evolution of lincRNAs...
Integrated analysis of pseudogene RP11-564D11.3 expression and its potential roles in hepatocellular carcinoma [0.03%]
RP11-564D11.3假基因的表达及其在肝细胞癌中潜在作用的综合分析
Hui Song,Jue Yang,Yongqiang Zhang et al.
Hui Song et al.
Aim: We aim to identify differentially expressed pseudogenes and investigate their functional roles in carcinogenesis. Materials & methods: ...
The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation [0.03%]
儿童全基因组DNA甲基化水平的社会经济地位和家庭环境因素的影响研究
Nicole R Bush,Rachel D Edgar,Mina Park et al.
Nicole R Bush et al.
Aim: To examine variation in child DNA methylation to assess its potential as a pathway for effects of childhood social adversity on health across the life course. ...
DNA methyltransferases and gastric cancer: insight into targeted therapy [0.03%]
dna甲基转移酶与胃癌：靶向治疗新策略
Sadegh Fattahi,Monireh Golpour,Fatemeh Amjadi-Moheb et al.
Sadegh Fattahi et al.
Gastric cancer is a major health problem worldwide occupying most frequent causes of cancer-related mortality. In addition to genetic modifications, epigenetic alterations catalyzed by DNA methyltransferases (DNMTs) are a well-characterized...
TIP60: an actor in acetylation of H3K4 and tumor development in breast cancer [0.03%]
TIP60在组蛋白H3K4乙酰化和乳腺肿瘤发生中的作用
Gaëlle Judes,Lucas Dubois,Khaldoun Rifaï et al.
Gaëlle Judes et al.
Aim: The acetyltransferase TIP60 is reported to be downregulated in several cancers, in particular breast cancer, but the molecular mechanisms resulting from its alteration are still unclear. ...