Measured maternal prepregnancy anthropometry and newborn DNA methylation [0.03%]
孕前体格测量与新生儿DNA甲基化状况的关系研究
Edwina H Yeung,Weihua Guan,Sunni L Mumford et al.
Edwina H Yeung et al.
Aim: We examined maternal prepregnancy anthropometry and cord blood DNA methylation. Methods: Associations between maternal measures (i...
Expression profiles of exosomal miRNAs isolated from plasma of patients with desmoplastic small round cell tumor [0.03%]
来源于间叶性小圆细胞肿瘤患者血浆外泌体miRNA表达谱特征分析
Marta Colletti,Alessandro Paolini,Angela Galardi et al.
Marta Colletti et al.
Aim: Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive mesenchymal tumor, lacking biomarkers for diagnosis, treatment stratification and prognosis. We investigated the exosomal miRNA profile in plasma samp...
Katerina Grafanaki,Dimitrios Anastasakis,George Kyriakopoulos et al.
Katerina Grafanaki et al.
Protein synthesis is a central and dynamic process, frequently deregulated in cancer through aberrant activation or expression of translation initiation factors and tRNAs. The discovery of tRNA-derived fragments, a new class of abundant and...
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells [0.03%]
NSUN2缺乏对HEK293细胞中mRNA 5-甲基胞嘧啶修饰及基因表达谱的影响分析
Zhen Sun,Songlei Xue,Hui Xu et al.
Zhen Sun et al.
Aim: To study the biological function of NSUN2 in regulating gene expression and cell proliferation. Materials & methods: The NSUN2 gen...
Identification and regulation pattern analysis of long noncoding RNAs in meibomian gland carcinoma [0.03%]
睑板腺癌中长链非编码RNA的鉴定及调控模式分析
Xin Song,Jiayan Fan,Renbing Jia et al.
Xin Song et al.
Aim: To identify long noncoding RNAs (lncRNAs) and to elucidate regulation patterns of lncRNAs in meibomian gland carcinoma (MGC). Materials & methods: ...
Integrated comparison of the miRNAome and mRNAome in muscles of dermatomyositis and polymyositis reveals common and specific miRNA-mRNAs [0.03%]
集成比较皮肌炎和多发性肌炎肌肉中的miRNA和mRNA可揭示共同的和特异的miRNA-mRNA组合关系
Siming Gao,Huali Zhang,Xiaoxia Zuo et al.
Siming Gao et al.
Aim: Dermatomyositis (DM) and polymyositis (PM) are refractory systemic autoimmune diseases with unknown pathogenesis. miRNAs is an important epigenetic mechanism to regulate gene expression. ...
Methylation profiles of IL33 and CCL26 in bronchial epithelial cells are associated with asthma [0.03%]
IL33和CCL26在支气管上皮细胞中的甲基化特征与哮喘相关
Miriam Larouche,Valérie Gagné-Ouellet,Anne-Marie Boucher-Lafleur et al.
Miriam Larouche et al.
Aim: This study aimed to characterize DNA methylation (DNA-me) in promoter region of IL33, IL1RL1 and CCL26 in asthma and their impacts on transcriptional activity in bronchial epithelial cells (BECs). ...
Epigenetic meta-analysis across three civilian cohorts identifies NRG1 and HGS as blood-based biomarkers for post-traumatic stress disorder [0.03%]
基于三个平民队列的表观遗传meta分析鉴定出两个 PTSD 血浆生物标志物基因 NRGI 和 HGS
Monica Uddin,Andrew Ratanatharathorn,Don Armstrong et al.
Monica Uddin et al.
Aim: Trauma exposure is a necessary, but not deterministic, contributor to post-traumatic stress disorder (PTSD). Epigenetic factors may distinguish between trauma-exposed individuals with versus without PTSD. ...
Meta-Analysis
Epigenomics. 2018 Dec;10(12):1585-1601. DOI:10.2217/epi-2018-0049 2018
Circular RNA circRHOT1 is upregulated and promotes cell proliferation and invasion in pancreatic cancer [0.03%]
Circular RNA circRHOT1在胰腺癌中表达上调并促进细胞增殖和侵袭
Shibin Qu,Xiaokun Hao,Wenjie Song et al.
Shibin Qu et al.
Aim: We aimed to identify the roles of circRHOT1 in pancreatic cancer. Materials & methods: The circRHOT1 was acquired from our previou...
DNA methylation/hydroxymethylation regulate gene expression and alternative splicing during terminal granulopoiesis [0.03%]
DNA甲基化/羟甲基化调节终末粒细胞分化过程中的基因表达和可变剪接
Dadi Gao,Natalia Pinello,Trung V Nguyen et al.
Dadi Gao et al.
Aim: To determine whether epigenetic modifications of DNA regulate gene expression and alternative splicing during terminal granulopoiesis. Materials & me...