Differential action of pro-angiogenic and anti-angiogenic components of Danhong injection in ischemic vascular disease or tumor models [0.03%]
丹参注射液促血管生成与抗血管生成成分的分化作用及机制研究
Shuang He,Rongrong Chen,Li Peng et al.
Shuang He et al.
Objective: We investigate the chemical basis and mechanism of angiogenesis regulation by a multicomponent Chinese medicine Danhong injection (DHI). Method...
Echinacoside exhibits antidepressant-like effects through AMPAR-Akt/ERK-mTOR pathway stimulation and BDNF expression in mice [0.03%]
环萼草苷通过AMPAR-Akt/ERK-mTOR途径刺激和脑源性神经营养因子表达在小鼠体内表现出抗抑郁样作用
Han-Wen Chuang,Tse-Yen Wang,Chih-Chia Huang et al.
Han-Wen Chuang et al.
Background: Several natural products have been demonstrated to be effective in the treatment of depressive disorders. Echinacoside, a naturally occurring phenol extracted from Cistanche tubulosa, Echinacea angustifolia, a...
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway [0.03%]
清萎散通过作用于TLR4/MyD88/NF-κB信号通路治疗糖尿病小鼠胃热型口腔溃疡
Lu Shi,Yongcheng An,Long Cheng et al.
Lu Shi et al.
Background: Qingwei San (QWS), one of classic Chinese Medicine prescripts, has been widely used to treat stomach heat syndrome which manifests oral ulcer (OU), periodontitis and upper gastrointestinal bleeding for seven h...
Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation [0.03%]
通过抑制PI3K/AKT/NF-кB激活重新利用一种临床批准的药材雀肾片治疗糖尿病肾脏疾病
Zhaochen Ma,Yudong Liu,Congchong Li et al.
Zhaochen Ma et al.
Background: Growing clinical evidences show the potentials of Colquhounia root tablet (CRT) in alleviating diabetic kidney disease (DKD). However, its pharmacological properties and underlying mechanisms remain unclear. ...
Correction to: Shen-Zhi-Ling oral liquid ameliorates cerebral glucose metabolism disorder in early AD via insulin signal transduction pathway in vivo and in vitro [0.03%]
Correction to: 盲目使用市场主导的生物标志物可能会误导阿尔茨海默病的治疗——来自 Shen-Zhi-Ling口服液体内和体外研究的证据
Gaofeng Qin,Yunfang Dong,Zhenhong Liu et al.
Gaofeng Qin et al.
Published Erratum
Chinese medicine. 2021 Dec 31;16(1):144. DOI:10.1186/s13020-021-00551-x 2021
Transcriptome analysis reveals the molecular mechanism of Yiqi Rougan decoction in reducing CCl4-induced liver fibrosis in rats [0.03%]
基于益气柔肝汤干预CCl4致大鼠肝纤维化模型的转录组分析
Yu Xiong,Jinyuan Hu,Chen Xuan et al.
Yu Xiong et al.
Background: Liver fibrosis develops from various chronic liver diseases, and there is currently a lack of specific treatment strategies. Yiqi Rougan decoction (YQRG) is a traditional Chinese medicine that has shown durati...
Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism [0.03%]
矿物辅料对中药炮制的影响研究：成分、药效及机制初探
Yan Liu,Xiaojie Li,Cai Chen et al.
Yan Liu et al.
Traditional Chinese medicines are an important class of natural products mainly derives from animals, plants and minerals, most of which need to be improved and processed before clinical use due to their own hard texture, impurities or toxi...
Ning Cui,Tiezhu Chen,Baosheng Liao et al.
Ning Cui et al.
Background: The decrease of wild reserves and the sharp increase of market demand have led to resource substitution, but it is still not clear how to discover medicinal alternative resources. Here we reveal the biology of...
A review of Chinese medicine for the treatment of psoriasis: principles, methods and analysis [0.03%]
中医药治疗银屑病的研究进展：原则、方法与分析
Yang Su,Wen Qin,Lun Wu et al.
Yang Su et al.
Chinese medicine (CM) has a long history in the treatment of psoriasis, and its different understanding angle and treatment mode from modern medicine have unique wisdom. In this article, we consulted a large number of literatures and collec...
Chinese herbal medicine for functional dyspepsia: a network meta-analysis of prokinetic-controlled randomised trials [0.03%]
功能性消化不良的中药治疗：随机对照试验的网络meta分析（促动力药物为标准）
Leonard Ho,Claire C W Zhong,Charlene H L Wong et al.
Leonard Ho et al.
Background: Prokinetic is the first-line conventional treatment for functional dyspepsia (FD) in Asia despite potential adverse events. Chinese herbal medicine (CHM) may be an effective and safe substitution. This network...