XuanHuGPT: parameter-efficient fine-tuning of large language model in the field of traditional Chinese medicine [0.03%]
玄乎GPT:中医领域的参数高效微调大型语言模型
Xuming Tong,Xiaozheng Ding,Huiru Jia et al.
Xuming Tong et al.
Large Language Models (LLMs) have demonstrated exceptional generalization capabilities across various fields, including their application in Traditional Chinese Medicine (TCM). However, the performance of existing LLMs in TCM-specific tasks...
Acupuncture reduces neuroinflammation and apoptosis, regulates peripheral immunity, and modulates T-cell subset distribution in vascular dementia rats [0.03%]
针刺通过减少神经炎症和凋亡、调节外周免疫以及改变血管性痴呆模型小鼠T细胞亚群分布发挥作用
Xinliang Wang,Xiaoxi Liu,Wenyu Zhang et al.
Xinliang Wang et al.
Background: Vascular dementia (VD), primarily caused by cerebral hypoperfusion, is a major dementia subtype. Our previous studies demonstrated that acupuncture improves clinical outcomes in VD patients and modulates their...
Holistic concept guided quality control of traditional Chinese medicines for optimizing bioavailability [0.03%]
整体观念指导的传统中药质量控制以优化药效物质的生物利用度
Yawen Tian,Juan Yao,Qian Gao et al.
Yawen Tian et al.
Traditional Chinese medicines (TCM) exerts multiple pharmacological effects, including anti-inflammation, antioxidation, and immune regulation, etc. However, its clinical efficacy and safety depend not only on the synergy of active substanc...
Clinical evaluation of a Clematis chinensis Osbeck-containing mouthwash for the prevention of dental caries: a randomized, controlled clinical trial [0.03%]
含柳叶菜素牙膏预防龋齿的临床评价:随机对照试验
Yu-Rin Kim,Seoul-Hee Nam
Yu-Rin Kim
Background: Chlorhexidine is widely used as a chemical antibacterial mouthwash, but its potential side effects have spurred interest in safer natural alternatives. ...
A novel algorithm- specific loci screening accelerates the establishment of molecular quantification of Glycyrrhiza glabra, G. uralensis, and G. inflata [0.03%]
一种新的算法特异性位点筛选加速了甘草、胀果甘草和光果甘草分子定量标志物的确立
Yifei Pei,Ziyi Liu,Wenjun Jiang et al.
Yifei Pei et al.
Objective: This study aims to establish a specialized molecular method for distinguishing different licorice and quantifying target species accurately from mixtures. ...
Spinal dorsal horn IGF1 mediates the preventive effect of electroacupuncture on cisplatin-induced peripheral neuropathy via neuronal IGF1R in mice [0.03%]
电针通过神经元IGF1R介导脊髓背角的IGF1预防顺铂外周神经病变的作用及机制研究
Chieh-Ru Fu,Xiao-Chen Li,Ya-Chen Yang et al.
Chieh-Ru Fu et al.
Background: Our previous study demonstrated that neuronal G protein-coupled receptor kinase (GRK2) upregulation alleviated chemotherapy-induced peripheral neuropathy (CIPN) in mice, which was characterized by numbness and...
The conversion of evodiamine-induced hepatotoxicity into a therapeutic effect on colonitis: insight from the liver-gut axis mediated by PPAR/NF-κB/ZO-1/caspase-3 pathway [0.03%]
吴莫因致肝毒性的肠炎治疗功效转化:PPAR/NF-κB/ZO-1/caspase-3通路介导的肝-肠轴视角
Chongjun Zhao,Qiqi Fan,Ying Dong et al.
Chongjun Zhao et al.
Background: Evodiamine (EVO) exerts promising therapeutic potential in the treatment of Ulcerative Colitis (UC). However, its clinical application is constrained by concerns regarding potential hepatotoxicity. A comprehen...
Correction: Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer [0.03%]
纠正:白头翁汤及其活性成分β-儿茶素诱导胰腺癌细胞G2 / M周期阻滞和凋亡
Rong Wu,Zhichao Xi,Mengfan Liu et al.
Rong Wu et al.
Published Erratum
Chinese medicine. 2025 Nov 20;20(1):205. DOI:10.1186/s13020-025-01207-w 2025
Computerized tongue image analysis for non-invasive disease screening: a review [0.03%]
计算机化舌象分析在非侵入性疾病筛查中的应用:综述
Huangbo Lin,Zhihan Ning,Chenglong Zhang et al.
Huangbo Lin et al.
The characteristics of the tongue surface and sublingual vein patterns provide valuable insights into an individual's health status and have long served as the cornerstone of traditional tongue diagnosis. As a non-invasive digital biomarker...
Decoding multicomponent crosstalk: integrated pharmacodynamic‒pharmacokinetic network of sour jujube seed [0.03%]
多成分药效学-药代动力学网络解码:酸枣仁研究案例分析
Yansheng Wu,Lijun Sun,Yimian Ma et al.
Yansheng Wu et al.
Ziziphus jujuba var. spinosa seed (SJS) is a multicomponent traditional remedy with diverse pharmacological activities, including sedative, neuroprotective, anxiolytic, and cardiometabolic effects. However, identifying the bioactive constit...