A systematic review on the application, phytochemistry and pharmacological activities of the genus Atractylodes [0.03%]
苍术属药用植物的应用、化学和药理作用的系统评价研究
Siwei Luo,Jiameng Jiang,Dongmei Zhang et al.
Siwei Luo et al.
The genus Atractylodes (Asteraceae) is widely distributed and utilized in East and Southeast Asia, particularly in China, Japan, Korea and Thailand. In traditional Chinese medicine, representative species such as A. lancea and A. macrocepha...
Remote electroacupuncture conditioning protects the heart via fine-tuning the dual role of the SDF-1α/CXCR4 axis in myocardial ischemia-reperfusion injury [0.03%]
远程电针调节通过调控SDF-1α/CXCR4轴的双重作用保护心肌缺血再灌注损伤
Senlei Xu,Jianfeng Lian,Shiyu Chen et al.
Senlei Xu et al.
Background: Remote electroacupuncture (EA) conditioning on forearm protects against myocardial ischemia-reperfusion injury (MIRI). However, the cardioprotective mechanisms of RIC have not been fully elucidated. This study...
Acupuncture regulates mitochondrial homeostasis in traumatic brain injury: current evidence, mechanistic hypotheses, and translational challenges [0.03%]
针灸调节创伤性脑损伤中的线粒体稳态：现有证据、机制假说和转化挑战
Guanglei Li,Luxi Cao,Sisi Zhao et al.
Guanglei Li et al.
Background: Traumatic brain injury (TBI) is associated with high morbidity, disability, and long-term neurological sequelae. Mitochondrial dysfunction is a central component of secondary injury after TBI, contributing to ...
Advances in Chinese herbal medicine for diabetic wound treatment: from tradition to innovation [0.03%]
糖尿病创面治疗的中医药研究进展：从传统到创新
Zhiqun Hong,Xinyi Liu,Bo Liu et al.
Zhiqun Hong et al.
Diabetic wounds represent one of the most intractable complications of diabetes, arising from a highly complex and self-perpetuating pathological microenvironment. This milieu is characterized by chronic inflammation, oxidative stress, impa...
Yiqi Huoxue Jiedu formula protects against sepsis-associated lung injury by modulating macrophage mitophagy and mtDNA-STING signaling [0.03%]
益气活血解毒方通过调节巨噬细胞线粒体自噬和mtDNA-STING信号通路防治脓毒症肺损伤
Shuqi Ma,Qiusha Pan,Jingnan Lin et al.
Shuqi Ma et al.
Background: Yiqi Huoxue Jiedu Formula (YHJF) is a traditional Chinese medicine formula that has been used as an adjunctive therapy for sepsis for nearly two decades. Previous clinical studies showed that YHJF improves Seq...
Self-assembled structures as a material basis for indirect pharmacology in Traditional Chinese Medicine [0.03%]
自组装结构可能是传统中医药间接药理学的物质基础
Jian Li,Wei Zhang,Jiayu Ye et al.
Jian Li et al.
Indirect pharmacology is increasingly invoked to explain how Traditional Chinese Medicine (TCM) and natural products produce therapeutic effects through inter-organ communication and distributed physiological regulation rather than through ...
Forsythoside A alleviates experimental autoimmune encephalomyelitis by targeting Tnfaip2 [0.03%]
山银花成分 Forsythoside A 通过作用于 TNFAIP2 抑制实验性自身免疫性脑脊髓炎
Ping Tang,Guibao Luo,Huihui Xue et al.
Ping Tang et al.
Background: Multiple sclerosis (MS) is a debilitating neuroinflammatory disease. Experimental autoimmune encephalomyelitis (EAE) is a commonly used rodent model for MS. Forsythoside A (FA), a natural compound derived from...
Macrophage membrane-functionalized biomimetic Yiqi Huoxue formula nanoparticles improve atherosclerosis by regulating smooth muscle cell phenotypic transition via the KLF4/NF-κB pathway [0.03%]
巨噬细胞膜修饰的益气活血方纳米粒通过KLF4/NF-κB信号通路调节血管平滑肌表型转换抑制动脉粥样硬化斑块进展
Yanqing Li,Hongyuan Wang,Yi Guan et al.
Yanqing Li et al.
This study aimed to analyze the active ingredients of the compound preparation of Yiqi Huoxue (YQHX) and evaluate the therapeutic effect of its nanoparticles (MM/YQHXF-NPs) on atherosclerosis (AS). First, the active ingredient in the YQHX f...
Yiyi Fuzi Baijiang formula protects against DSS-induced colitis by orchestrating the gut barrier-microbiota-metabolism axis [0.03%]
益茯白奖方通过调控肠屏障-菌群-代谢轴防治DSS诱导的结肠炎
Yin Bao,Qiang Ao,Meng Wang et al.
Yin Bao et al.
Background: Inflammatory bowel disease (IBD) is a relapsing inflammatory disorder of the gastrointestinal tract with increasing global incidence. Current therapies are often limited by side effects, loss of efficacy, and ...
Medicine-food homologous bioactives in metabolic dysregulation-associated osteoporosis: a review of preclinical evidence and potential liver-bone and gut-bone actions [0.03%]
代谢紊乱相关骨质疏松症的食药同源活性成分：前期证据及潜在肝-骨和肠-骨作用的综述
Wen Fan,Beilei Shi,Ze Gao et al.
Wen Fan et al.
Background: Osteoporosis is increasingly linked to metabolic dysregulation. Medicine-food homologous (MFH) materials contain diverse natural bioactives with reported osteoprotective effects, but their overall evidence lan...