Syringaresinol alleviates acetaminophen-induced hepatocyte ferroptosis through the Nrf2/HO-1 pathway by targeting Caveolin-1 [0.03%]
通过靶向Caveolin-1激活Nrf2/HO-1通路缓解对乙酰氨基酚诱导的肝细胞铁死亡中的Syriezresinol作用研究
Lei Cao,Jiawei Zhang,Peng Song et al.
Lei Cao et al.
Ferroptosis is reported to be closely involved in acetaminophen (APAP) overdose induced liver injury. The development of hepatoprotective drugs that target ferroptosis inhibition is highly valuable. In our previous work, we have confirmed t...
Baicalein mitigates epithelial barrier impairment and microbiota dysbiosis in allergic asthmatic mice via the gut‑lung axis [0.03%]
黄芩素通过肠-肺轴缓解过敏性哮喘小鼠上皮屏障功能障碍和微生物群失调
Yao Lu,Xinqian Rong,Lini Wei et al.
Yao Lu et al.
Background: Allergic asthma (AA) may result in repeated episodes of chest constriction and coughing. In its most serious manifestations, it can cause death by asphyxiation. Currently, no efficacious therapeutic interventi...
Targeted degradation of aberrant Tau for the discovery of Pulsatilla chinensis in Alzheimer's disease [0.03%]
针对阿尔茨海默病异常Tau蛋白的牵牛菊根提取物靶向降解研究
Lan Deng,Can Yin,Xiaogang Zhou et al.
Lan Deng et al.
Background: Alzheimer's disease (AD) is characterized by Tau aggregation, mitochondrial dysfunction, and oxidative stress, yet effective interventions targeting these pathological cascades remain limited. Therapeutic stra...
Narcissoside attenuates atherosclerosis by suppressing CD36-mediated foam cell formation via upregulation of NR4A1 [0.03%]
narcissoside通过上调NR4A1抑制CD36介导的泡沫细胞形成从而缓解动脉粥样硬化
Ziyuan Wang,Lamei Zhou,Xiaorong Zhang et al.
Ziyuan Wang et al.
Background: The formation of foam cells (FCs) is the major contributor to the development of atherosclerosis (AS). Gynostemma pentaphyllum is widely used to treat AS and exhibits biological activity against FCs formation....
Mechanism of Qiling Fuzheng Qingjie granules in alleviating doxorubicin-induced T cell immune dysfunction via mitochondrial energy metabolism [0.03%]
祁连复正清杰颗粒通过线粒体能量代谢改善多柔比星致T细胞免疫功能障碍的机制研究
Ruiming Yang,Jie Yuan,Ruihan Sun et al.
Ruiming Yang et al.
This study investigates the mechanism by which Qiling Fuzheng Qingjie Granule (QFQ) regulates immune function following doxorubicin (DOX) chemotherapy. Network pharmacology analysis was employed to explore the relationship between QFQ and t...
CHRNA3⁺ nociceptors prime the cutaneous sensory interface to enhance electroacupuncture analgesia [0.03%]
CHRNA3+伤害性感受器激活电针镇痛效应
Wenjie Xu,Dingdan Zhang,Yuanwei Tang et al.
Wenjie Xu et al.
Background: Recent evidence determined that acupoints frequently overlap with regions of referred somatic hypersensitivity induced by visceral disease, a phenomenon known as acupoint sensitization. This state is typically...
Ginsenosides in the management of depression: a comprehensive pharmacological review [0.03%]
人参皂苷在抑郁症管理中的作用：全面药理学综述
Min Ren,Xin Tao,Hong Chang et al.
Min Ren et al.
Depression is a prevalent and debilitating psychiatric disorder that is frequently accompanied by chronic conditions such as cancer, cardiovascular diseases, and neurological disorders. Despite the availability of various pharmacological tr...
Correction: Fuzheng Huayu formula ameliorates chronic cholestatic liver injury by upregulating PPARa in mice [0.03%]
补正：复征化瘀方通过上调PPARα治疗慢性胆汁淤积性肝损伤（小鼠）
Zheng Zhang,En-Qi Tang,Chun-Hui Li et al.
Zheng Zhang et al.
Published Erratum
Chinese medicine. 2026 May 14;21(1):132. DOI:10.1186/s13020-026-01419-8 2026
CVB-D attenuates experimental diabetic cardiomyopathy by alleviating mitochondrial dysfunction via the JAK1-STAT1 signaling axis in vivo and in vitro [0.03%]
CVB-D通过体内和体外实验中的JAK1-STAT1信号轴减轻线粒体功能障碍来缓解糖尿病心肌病
Hang Su,Chun-Qiang Zhang,Jiang-Fei An et al.
Hang Su et al.
Background: Diabetic cardiomyopathy (DCM), as a prevalent cardiovascular complication in diabetes, involves cardiomyocyte dysfunction as a central pathological feature. Cyclovirobuxine D (CVB-D) is a naturally occurring b...
Data-driven full-chain quality control for Xiaoer Chiqiao Qingre granules: from process risk management to intelligent product testing [0.03%]
基于数据驱动的“小儿赤热清颗粒”全流程质量控制研究：从过程风险管理到智能产品检测
Nan Wang,Yukun Chang,Yue Cheng et al.
Nan Wang et al.
Background: Xiaoer Chiqiao Qingre granules (XECQ) is a widely used traditional Chinese medicine for the treatment of pediatric wind-heat colds. However, its multi-step manufacturing process results in substantial inter-ba...