Ethanol extract of Astragali Radix inhibits M1 macrophage polarization to alleviate ulcerative colitis by promoting Lactobacillus reuteri-produced indole-3-carboxaldehyde and formononetin [0.03%]
黄芪乙醇提取物通过促进罗伊氏乳杆菌产生色氨甲酸和形式宁来抑制M1型巨噬细胞极化从而改善溃疡性结肠炎
Jia-Xuan Zhang,Shi-Qin Dong,Yin-Xia Hu et al.
Jia-Xuan Zhang et al.
Background: Astragali Radix (AR) is a traditional Chinese medicine used to treat ulcerative colitis (UC). However, the effectiveness of its ethanol extract in relieving UC and its mechanisms involved are not well comprehe...
Exploring the mechanism of Qinlian Yuyang Decoction in the treatment of ulcerative colitis based on multi-omics technology [0.03%]
基于多组学技术的秦连愈疡方治疗溃疡性结肠炎机制研究
Ya-Ting Cao,Xin Huang,Cheng-Li Yu et al.
Ya-Ting Cao et al.
Background: The global incidence of ulcerative colitis (UC) is increasing, yet effective clinical treatment options remain limited. Qinlian Yuyang Decoction (QYD), a modified formulation based on Gegen Qinlian Decoction (...
The IL-17 pathway mediated by m6A-modified lncRNA H19: a new mechanism for Jianpi Qingre Tongluo Prescription in repressing inflammation and improving lipid metabolism in gout arthritis [0.03%]
由m6A修饰的长链非编码RNA H19介导的IL-17通路：健脾清热通络方抑制痛风性关节炎炎症及改善脂质代谢的新机制
Xianheng Zhang,Jian Liu,Xiaolu Chen et al.
Xianheng Zhang et al.
Background: Jianpi Qingre Tongluo Prescription [also named Huangqin Qingrechubi Capsule (HQC)] is an empirical prescription for the treatment of gouty arthritis (GA) with excellent clinical efficacy. Mechanistically, HQC ...
Zhen-Wu-Tang ameliorates uremic cardiomyopathy via targeting the kidney-heart inflammatory axis and suppressing CCL2/CCR2-mediated macrophage activation [0.03%]
真武汤通过靶向肾心炎症轴并抑制CCL2/CCR2介导的巨噬细胞活化来改善尿毒症性心肌病
Yu Xu,Jing Cai,Yuan-Ming Fan et al.
Yu Xu et al.
Background: Zhen-Wu-Tang (ZWT), a classic herbal formula from Treatise on Febrile and Miscellaneous Diseases, is commonly used for heart and kidney-related diseases. Despite its widespread application, research on the act...
Targeting the ferritinophagy axis: multi-target regulation of TFRC/FTH1/NCOA4 by artesunate ameliorates salivary gland dysfunction in Sjögren's Disease [0.03%]
艺术木通过多靶点调节TFRC/FTH1/NCOA4通路抑制干脾小鼠唾液腺铁死亡以改善口干燥症病情
Yong Luo,Liuting Zeng,Yaru Zheng et al.
Yong Luo et al.
Background: Sjögren's Disease (SJD) is an autoimmune disorder involving lymphocytic infiltration of exocrine glands, notably salivary and lacrimal glands, causing dysfunction. Ferroptosis, an iron-dependent cell death pa...
Pleiotropic pharmacological activities and multiple-organ toxicities of triptolide: a programmed cell death perspective [0.03%]
从程序性细胞死亡的角度看三七茋的多效药理活性及对多个器官的毒性作用
Yuan Mao,LiWen Huang,HongPing Long et al.
Yuan Mao et al.
Triptolide, a bioactive triepoxide diterpenoid extracted from Tripterygium wilfordii Hook. f., has demonstrated broad pharmacological activities and significant toxicities. Mechanistically, triptolide has exerted therapeutic effects by regu...
Correction: Liriodendron attenuates intestinal fibrosis and inflammation in mice with radiation proctopathy [0.03%]
补遗：Liriodendron减轻放射性直肠病小鼠的肠道纤维化和炎症
Hao Huang,Junsheng Li,Yanling Zhang et al.
Hao Huang et al.
Published Erratum
Chinese medicine. 2026 Mar 17;21(1):92. DOI:10.1186/s13020-026-01366-4 2026
Regulatory mechanisms of Traditional Chinese Medicine on gut microbiota in diabetic microvascular complications [0.03%]
中医药对糖尿病微血管并发症的肠道菌群调节机制
Yiyang Peng,Chenyao Sun,Zheng Wang et al.
Yiyang Peng et al.
Diabetic microvascular complications are the most common and serious late-stage problems with diabetes patient, while existing antidiabetic treatments still have limited effects in preventing or reversing microvascular damage. Traditional C...
Guominkang formula alleviates airway inflammation in HDM-induced asthma mice by regulating Wnt/β-Catenin pathway [0.03%]
国康方通过调节Wnt/β-Catenin信号通路治疗HDM致小鼠哮喘作用的研究
Yuhan Zong,Jingwei Kong,Fan Yang et al.
Yuhan Zong et al.
Background: The Guominkang formula (GMK), formulated according to the principle of "treatment based on constitution differentiation," comprises Prunus mume (Siebold) Siebold & Zucc. (Wumei), Saposhnikovia divaricata (Turc...
Fuzheng Huayu formula ameliorates chronic cholestatic liver injury by upregulating PPARa in mice [0.03%]
补肝化瘀方通过上调PPARα改善小鼠慢性胆汁淤积性肝损伤
Zheng Zhang,En-Qi Tang,Chun-Hui Li et al.
Zheng Zhang et al.
Background: Fuzheng Huayu formula (FZHY) has been extensively applied in clinical for liver fibrosis treatment in China, its therapeutic potential in cholestatic liver injury remains underexplored. ...