Peng Xue,Eddy Sánchez-León,Djihane Damoo et al.
Peng Xue et al.
Fungal pathogens cause life-threatening diseases in humans, and the increasing prevalence of these diseases emphasizes the need for new targets for therapeutic intervention. Nutrient acquisition during infection is a promising target, and r...
The rise in cases of mucormycosis, candidiasis and aspergillosis amidst COVID19 [0.03%]
COVID-19大流行中毛霉病，念珠菌感染和曲霉病病例的增加
Asmita Ghosh,Anusua Sarkar,Pubali Paul et al.
Asmita Ghosh et al.
The Coronavirus outbreak globally has changed the medical system and also led to a shortage of medical facilities in both developing and underdeveloped countries. The COVID19 disease, being novel in nature along with high infectivity and fr...
Evolving challenges and strategies for fungal control in the food supply chain [0.03%]
食品供应链中真菌控制的挑战与策略演变
Catheryn R Davies,Franziska Wohlgemuth,Taran Young et al.
Catheryn R Davies et al.
Fungi that spoil foods or infect crops can have major socioeconomic impacts, posing threats to food security. The strategies needed to manage these fungi are evolving, given the growing incidence of fungicide resistance, tightening regulati...
Radames Jb Cordero,Arturo Casadevall
Radames Jb Cordero
Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in microbial pathogenesis is well established; however, these complex biomolecules also confer upon fungal microorganisms the faculty to tolerate e...
Sophie Altamirano,Srikripa Chandrasekaran,Lukasz Kozubowski
Sophie Altamirano
While mechanisms of cytokinesis exhibit considerable plasticity, it is difficult to precisely define the level of conservation of this essential part of cell division in fungi, as majority of our knowledge is based on ascomycetous yeasts. H...
Evolution of sexual reproduction: a view from the Fungal Kingdom supports an evolutionary epoch with sex before sexes [0.03%]
性生殖的进化：来自真菌王国的观点支持了一个具有性别之前的性时代的进化时代
Joseph Heitman
Joseph Heitman
Sexual reproduction is conserved throughout each supergroup within the eukaryotic tree of life, and therefore thought to have evolved once and to have been present in the last eukaryotic common ancestor (LECA). Given the antiquity of sex, t...
Sheng Sun,Joseph Heitman
Sheng Sun
While sexual reproduction is universal in eukaryotes, and shares conserved core features, the specific aspects of sexual reproduction can differ dramatically from species to species. This is also true in Fungi. Among fungal species, mating ...
Contrasted patterns in mating-type chromosomes in fungi: hotspots versus coldspots of recombination [0.03%]
真菌交配型染色体对比模式：重组的热点与冷点
Alexander Idnurm,Michael E Hood,Hanna Johannesson et al.
Alexander Idnurm et al.
It is striking that, while central to sexual reproduction, the genomic regions determining sex or mating-types are often characterized by suppressed recombination that leads to a decrease in the efficiency of selection, shelters genetic loa...
Orchestration of Morphogenesis in Filamentous Fungi: Conserved Roles for Ras Signaling Networks [0.03%]
丝状真菌形态发生的调控：Ras信号网络的作用机制及其保守性
Jarrod R Fortwendel
Jarrod R Fortwendel
Filamentous fungi undergo complex developmental programs including conidial germination, polarized morphogenesis, and differentiation of sexual and asexual structures. For many fungi, the coordinated completion of development is required fo...
Karthik Krishnan,David S Askew
Karthik Krishnan
The gateway to the secretory pathway is the endoplasmic reticulum (ER), an organelle that is responsible for the accurate folding, post-translational modification and final assembly of up to a third of the cellular proteome. When secretion ...