Senescence of dental pulp stem cells: phenotypes, underlying mechanisms and regulatory molecules [0.03%]
牙髓干细胞衰老的表型、潜在机制及调控分子
Ping Zhang,Yu Cui,Zekun Li et al.
Ping Zhang et al.
Dental pulp stem cells (DPSCs) are a population of adult stem cells with self-renewal capacity and multilineage differentiation potential, widely utilized in tissue engineering and regenerative medicine. However, with increasing donor age o...
Multi-epitope vaccines: charting a new frontier in monkeypox prevention and control [0.03%]
多抗原疫苗：绘制一个新的防治猴痘前沿领域
Pooja Tiwary,Krishil Oswal,Ryan Varghese et al.
Pooja Tiwary et al.
Monkeypox is a viral zoonotic infection that has emerged as a significant public health threat recently. The world has experienced a global outbreak of the Monkeypox virus (MPXV), with 124,753 confirmed cases in 128 countries and a total of...
Establishment and characterization of preclinical model of primary ovarian squamous cell carcinoma [0.03%]
原发性卵巢鳞状细胞癌的临床前模型的建立与表征
Chenyang Xu,Weiming Xu,Conghui Wu et al.
Chenyang Xu et al.
Primary ovarian squamous cell carcinoma (POSCC) represents an exceedingly rare subtype of epithelial ovarian cancer (EOC) characterized by a cryptic etiology and insidious onset. The rarity and high mortality associated with pure primary ov...
Exosomes derived from human umbilical cord mesenchymal stem cells inhibit hepatocyte pyroptosis via miR-423-5p/ZBP1 in acute liver failure [0.03%]
人脐带间充质干细胞源外泌体通过miR-423-5p/ZBP1抑制急性肝衰竭中的肝细胞焦亡
Dan Xie,Lina Yu,Ziyang Wang et al.
Dan Xie et al.
Human umbilical cord mesenchymal stromal cells (hucMSCs) have emerged as a promising therapeutic option for acute liver failure (ALF). However, the detailed mechanism by which hucMSCs modulate hepatocyte pyroptosis in ALF remains unclear. I...
CircTADA2A inhibits cell proliferation and promotes ferroptosis by sponging miR-638 in acute myeloid leukemia [0.03%]
环状RNA CircTADA2A通过海绵吸附miR-638抑制急性髓系白血病细胞增殖并促进铁死亡
Yuan Yuan,Jiajia Li,Meng Wang et al.
Yuan Yuan et al.
Dysregulation of circRNAs has been found to engage in the progression of many hematologic malignancies including acute myeloid leukemia (AML). In this study, we identified significantly downregulated circTADA2A, derived from linear transcri...
Establishment and characterization of NCC-EMC1-C1: a novel patient-derived cell line of extraskeletal myxoid chondrosarcoma [0.03%]
NCC-EMC1-C1的建立及特征分析：一种新型软骨肉瘤病人的衍生细胞系
Shuhei Iwata,Rei Noguchi,Julia Osaki et al.
Shuhei Iwata et al.
Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma characterized by a myxoid matrix and a distinctive lobulated architecture, composed of cords and clusters of uniform round-to-rhabdoid cells. At the molecular level, EM...
Generation of human-induced pluripotent stem cells from a patient with Beckwith-Wiedemann syndrome [0.03%]
来自贝克威斯-沃利伯格综合征患者的诱导多能干细胞的建立
Mei Tang,Jiafan Lei,Congwen Shao et al.
Mei Tang et al.
Beckwith-Wiedemann syndrome (BWS) is a human genomic imprinting disorder mainly caused by an imprinting abnormality in the chromosome 11p15.5 region. It is rare and sporadic with unclear etiology and pathogenesis. We identified a family wit...
Identification of autophagy-related biomarkers in prostate cancer prognosis [0.03%]
前列腺癌预后相关的自噬标记物识别
Yancheng Di,Linlin Zhao,Lingling Zhang et al.
Yancheng Di et al.
Prostate cancer is the second leading cause of cancer-related deaths in males that has an unfavorable outcome. Autophagy-related genes (ARGs) contribute to the process of tumorigenesis and metastasis of prostate cancer. This study aimed to ...
EZH2 regulates tumor-associated macrophages by the KDM6A-mediated inflammatory response in HPV16-positive cervical cancer [0.03%]
EZH2通过KDM6A介导的炎症反应调节人乳头瘤病毒16型阳性宫颈癌相关巨噬细胞的功能
Qing Tang,Ying Yang,Jia&#x;nan Sun
Qing Tang
High-risk HPV subtypes impact the immune response in cervical cancer. Tumor-associated macrophages (TAMs) are well known to contribute to tumor development by regulating the immune response. This study aimed to analyze the mechanism of TAMs...
Human metapneumovirus: a mini-review on the genetic and phylogenetic roots of a rising respiratory threat [0.03%]
人副流感病毒的遗传及系统发育起源：对日益严重的呼吸道威胁的综述性文章
Pooja Tiwary,Krishil Oswal,Ryan Varghese et al.
Pooja Tiwary et al.