Targeting ligand PDL1 for cardiotoxicity assessment and cardiac protection in immune-related myocarditis [0.03%]
用于免疫相关心肌炎的心脏毒性和心脏保护的靶向配体PDL1
Yi Li,Xiaoxin Li,Fei Liu et al.
Yi Li et al.
Aims: The role of cardiac programmed cell death ligand 1 (PDL1) in immune checkpoint inhibitor (ICI) - related myocarditis (irMyocarditis) remains unclear. We aimed to investigate whether ligand PDL1 could serve as an ear...
The research status and trends of engineered exosomes: a bibliometric analysis of the literature from web of science core collection [0.03%]
基于Web of Science核心合集的外泌体研究现状与趋势定量分析及可视化研究
Yu-Fan Ren,Bo Shao,Hong-da Wang et al.
Yu-Fan Ren et al.
Background: In recent years, engineered exosomes have addressed the limitations of natural exosomes and gradually emerged as a new research hotspot. A comprehensive bibliometric analysis can reveal research trends and hot...
A review of the application of nanotechnology-based, non-contact remote patient monitoring in intelligent nursing for the prevention of major adverse cardiovascular events [0.03%]
基于纳米技术的非接触远程患者监测在智能护理中预防主要不良心血管事件的应用评价
Xiaoya Liu,Li Min,Yuandong Tao et al.
Xiaoya Liu et al.
With the rapid advancement of remote patient monitoring (RPM) technologies, the integration of non-contact sensing methods and nanotechnology has emerged as a promising approach within intelligent nursing. This review highlights the latest ...
Mesenchymal stem cell-derived nanovesicles coated PLGA nanoparticle (MSC-PLGA-NPs) remodel lysosomal function to clear pathological proteins in Alzheimer's disease models [0.03%]
外泌体涂层的PLGA纳米颗粒通过重塑溶酶体功能清除阿尔茨海默病模型中的异常蛋白
Yuankai Gu,Mengqi Hao,Li Wang et al.
Yuankai Gu et al.
Aims: To develop a novel multifunctional nanoparticle platform by combining mesenchymal stem cell-derived nanovesicles (MSC-NVs) with poly(lactic-coglycolic acid) (PLGA) nanoparticles for Alzheimer's disease (AD) therapy....
Advancing RNA delivery with Ionizable lipid nanoparticles: the roles of microfluidics and machine learning [0.03%]
基于微流控和机器学习的离子脂质纳米颗粒RNA递送研究进展
Neda Rostami,Mehdi Alidadi,Haniye Barzegar et al.
Neda Rostami et al.
Ionizable lipid nanoparticles (iLNPs) have revolutionized Ribonucleic acid (RNA) therapeutics by enabling precise and efficient delivery of nucleic acids. However, their clinical translation remains challenged by batch-to-batch variability,...
COX-2 gene silencing by laser-assisted oligonucleotides release from remote optical Nano-switches (LORONS) in hepatocellular carcinoma cells [0.03%]
基于远程光控纳米开关释放寡核苷酸的激光辅助基因沉默技术抑制肝癌细胞中COX-2基因表达
Uzma Azeem Awan,Abida Raza,Shaukat Ali et al.
Uzma Azeem Awan et al.
Background: Overexpression of cyclooxygenase-2 (COX-2) has been associated with hepatocellular carcinoma (HCC). Selective inhibition of COX-2 can come forward as improved and targeted therapeutic strategy. ...
Connexome-associated pathways in atherosclerosis and potential regulatory nanomedicine-based strategies [0.03%]
动脉粥样硬化中的connexome相关通路及其潜在的纳米医学调控策略
Michelle G Santoyo-Suarez,Adriana G Quiroz Reyes,Mayela Del-Angel-Martinez et al.
Michelle G Santoyo-Suarez et al.
Atherosclerosis remains the primary cause of cardiovascular morbidity and mortality, with intercellular communication critically influencing vascular homeostasis and disease progression. The connexome comprises connexins, pannexins, and ass...
Employing low-density lipoprotein-based delivery systems for the treatment of hepatocellular carcinoma [0.03%]
基于低密度脂蛋白的递送系统在肝细胞癌治疗中的应用研究
Meghana Kolli,Tiyler Adams,Ian R Corbin
Meghana Kolli
Circulating plasma low-density lipoprotein (LDL) is a natural nanoscale carrier designed to transport cholesterol throughout the body through specific receptor mediated processes. During malignant transformation, cancer cells upregulate the...
Nanomedicine in the development of vaccines against Herpesviridae: a narrative review [0.03%]
纳米医学在疱疹病毒疫苗开发中的应用：叙述性综述研究
Diana Hsin-Yu Lee,William Lee,Horacio Bach
Diana Hsin-Yu Lee
The Herpesviridae family, more commonly known as herpesviruses, includes the Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae subfamilies, each with unique clinical presentations. Herpesvirus infections are a major public healt...
Shivam Sharma,Anil Kishen
Shivam Sharma
Oral inflammatory diseases such as periodontitis, peri-implantitis, and oral mucositis contribute significantly to tooth loss, impaired oral function, and systemic comorbidities. These conditions are driven by dysregulated immune responses,...