An overview of strategies and challenges adopted to silence BCR-ABL gene by small interfering RNA [0.03%]
用于沉默BCR-ABL基因的小干扰RNA的策略和挑战概述
Laura Fancello,Maria Manconi,Maria Letizia Manca
Laura Fancello
BCR-ABL oncogene associated with chronic myeloid leukemia (CML) encodes for tyrosine kinase with enhanced activity that drives the uncontrolled proliferation of white blood cells. The therapy with tyrosine kinase inhibitors improves the lif...
Breakthroughs in the nanoparticle-mediated delivery of siRNA for breast cancer treatment [0.03%]
纳米颗粒介导的siRNA递送治疗乳腺癌的研究进展
Davi Trombini Aleixo,Estael L C Cruz-Cazarim,Kezia C B Ferreira et al.
Davi Trombini Aleixo et al.
Although breast cancer treatments have improved, challenges like tumor heterogeneity and drug resistance remain. RNA interference (RNAi), especially through small interfering RNA (siRNA), is a promising strategy to silence specific genes an...
Silver nanoparticles: a new frontier in ophthalmic innovation and treatment [0.03%]
银纳米颗粒：眼科创新和治疗的新前沿
Tong Wang,Jian Cao,Fan Gan et al.
Tong Wang et al.
In recent years, the application of nanotechnology in biomedicine has been extensively studied. Silver nanoparticles (AgNPs), a novel type of nanomaterial, have garnered increasing attention in the field of ophthalmology because of their un...
Nanomaterials and nanotechnology in otolaryngology: a narrative review [0.03%]
耳鼻喉科中的纳米材料和纳米技术：叙述性综述
Nuray Bayar Muluk,Cemal Cingi
Nuray Bayar Muluk
We reviewed usage of nanomaterials and nanotechnology in otolaryngology. The literature search in this narrative review used Google, Google Scholar, PubMed, EBSCO, Proquest Central, Proquest Central, Web of Science and Scopus at Kırıkkale...
Applying click chemistry principles to the design of tumor-targeted nanosystems [0.03%]
借鉴点击化学原理设计靶向肿瘤的纳米系统
J J Diaz-Mochon,R M Sanchez-Martin
J J Diaz-Mochon
Hayley C Parkin,Pawel Swietach,Helen Townley
Hayley C Parkin
In vitro and in vivo study of theranostic silver sulfide nanoparticles loaded with methotrexate for synchronous chemoradiation [0.03%]
一种用于同步化疗和放疗的载聚谷氨酸亚甲基四氢叶酸银硫化物纳米粒子诊疗剂的研究
Ali Mohammadi,Vesal Hasani,Alimohammad Amirbostaghi et al.
Ali Mohammadi et al.
Aims: The development of multifunctional nanoplatforms capable of simultaneous therapeutic and diagnostic applications is a growing focus in biomedical research. ...
Nanoparticle-mediated magnetic hyperthermia in the treatment of neurological disorders [0.03%]
纳米颗粒介导的磁热疗在神经疾病治疗中的应用
Muhammad Naveed,Min-Ho Kim
Muhammad Naveed
Neurological disorders including gliomas and neurodegenerative diseases are characterized by dysregulation of the central nerve system (CNS). Despite recent advances in disease-modifying treatments, pharmacological approaches for neurologic...
Advancements in nanoultrasonics technology for the diagnosis and treatment of liver cancer: discussion on medical ethics and hospital management issues [0.03%]
纳超声技术在肝癌诊疗中的进展及医疗伦理和医院管理问题讨论
Weiping Wan,Fan Yang,Yenan Zhang et al.
Weiping Wan et al.
The field of nanoultrasonics technology has emerged as a promising avenue for enhancing the diagnosis and treatment of liver cancer, a disease characterized by high mortality rates and complex management challenges. Recent studies highlight...
Emerging applications of nanotechnology in the treatment of acute kidney injury [0.03%]
纳米技术在急性肾损伤治疗中的新兴应用
Lingxue Zeng,Jonghan Kim,Hak Soo Choi et al.
Lingxue Zeng et al.
Acute kidney injury (AKI) is a life-threatening condition with high mortality rates and limited treatment options. Recent advances in nanotechnology offer transformative potential for AKI therapy by enabling targeted drug delivery, enhancin...