USPIO enhanced MR imaging in CNS tumors (UMIC): a study protocol [0.03%]
一种用于中枢神经系统肿瘤的超小MRI对比剂增强MRA影像研究——UMIC项目方案
J Breese,W Lloyd,A Fothergill et al.
J Breese et al.
Tumor-associated macrophages (TAMs) are key drivers of brain tumor progression and therapy resistance. Clinically applicable biomarkers capable of evaluating TAM populations in vivo are highly sought, with one potential imaging marker being...
Overcoming the barriers to the scaled-up production of therapeutic bacterial extracellular vesicles [0.03%]
克服治疗性细菌外泌体规模化生产的壁垒
Kathrin Castiglione,Gregor Fuhrmann
Kathrin Castiglione
Single-entity analysis of therapeutic nanoparticles: from orthogonal metrology to AI [0.03%]
单一实体的治疗纳米粒子分析：从正交计量到人工智能
Rui Wang,Chunyan Zhu,Feng Zheng et al.
Rui Wang et al.
Therapeutic nanoparticles, including lipid nanoparticles (LNPs), polymeric nanocarriers, and inorganic nanomaterials, are intrinsically heterogeneous in size, mass, composition, and drug loading. However, their characterization still relies...
Impact of nanocarrier mediated drug delivery systems: a deep dive into therapeutics and clinical management of breast cancer [0.03%]
纳米载体介导的药物递送系统对乳腺癌治疗和临床管理的影响：深入探讨治疗方法
Sana Hanif,Nariman Shahid,Javed Iqbal et al.
Sana Hanif et al.
Breast cancer (BC) is the most frequently diagnosed malignancy and the leading cause of cancer-related death among women worldwide. The therapeutic limitations of conventional treatment modalities are due to systemic toxicity, multidrug res...
A Phase I trial of PLZ4-coated paclitaxel-loaded micelles in patients with refractory non-muscle-invasive bladder cancer [0.03%]
PLZ4包被紫杉醇载药胶束治疗难治性非肌层浸润性膀胱癌I期临床研究
Athira Narayan,Ryan C Leibrandt,Joyce S Lee et al.
Athira Narayan et al.
NCT06173349. Keywords: Micelles; bladder cancer; intravesical; targeted; taxane. Pl...
PLGA/PVA nanoparticles to deliver a protein-based cancer vaccine targeting GPC1 for the treatment of pancreatic ductal adenocarcinoma [0.03%]
用于治疗胰腺导管腺癌的靶向GPC1的蛋白质癌症疫苗的PLGA / PVA纳米颗粒输送系统
Marta Gambirasi,Idris Vruzhaj,Davide Busato et al.
Marta Gambirasi et al.
Introduction: Therapeutic cancer vaccines have been proposed to stimulate an immune response for controlling disease progression and reducing treatment recurrence in cancer, such as pancreatic ductal adenocarcinoma (PDAC)...
Sodium alginate functionalized biocompatible selenium nanocarriers loaded trans-resveratrol for mitochondrial targeted HepG2 hepatocellular carcinoma inhibition study [0.03%]
壳多糖硒纳米载药体系转运茋型白藜芦醇化合物对肝癌细胞线粒体靶向抑制作用的研究
Mahvish Fatima,Nosheen Kanwal,Eman Kashita et al.
Mahvish Fatima et al.
Aims: To investigate the use of sodium alginate (SA) for functionalization of selenium nanoparticles (SA@Se NPs) in developing biocompatible nanocarrier to enhance stability, mitochondrial targeting and anticancer efficac...
Extracellular vesicles targeting EGFR inhibit MAOA expression and activity by delivering curcumin for the treatment of asthma [0.03%]
靶向EGFR的细胞外囊泡通过递送姜黄素抑制MAOA表达及活性治疗哮喘
Rui Guo,Yinghui Wang,Guojie Hao et al.
Rui Guo et al.
Aims: To investigate whether curcumin (CUR) delivered by EGFR-targeted extracellular vesicles (EVs) alleviates asthma and to explore the underlying mechanism. ...
Advances in Prussian blue nanoparticle-based anticancer platforms: synthesis, functionalization, and therapeutic applications [0.03%]
基于普鲁士蓝纳米粒子的抗癌平台研究进展：合成、功能化及治疗应用
Chittathur Midhun Krishna,Rupa Mazumder,Rakhi Mishra et al.
Chittathur Midhun Krishna et al.
Introduction: Cancer is a disease that has plagued human health throughout history. Prussian blue is a pigment that has been studied for its uses and approved also to be biologically safe for human use, and has been resea...
The role of chitosan-based nano systems in emerging vaccine technologies: current status and future expectations [0.03%]
基于壳聚糖的纳米系统在新兴疫苗技术中的作用：现状与未来期望
Genada Sinani,Sevda Şenel
Genada Sinani
The multifunctional potential of chitosan, which is a natural biopolymer derived from chitin, in the field of vaccine formulation will be explored in this review. Firstly, how this unique chemically versatile structure of chitosan allows sc...