Formononetin-derived quantum dots suppress colon cancer growth by triggering mitochondrial apoptosis [0.03%]
.formononetin衍生的量子点通过触发线粒体凋亡抑制结肠癌生长
Junfeng Zhang,Yuqing Cui,Chenchen Li et al.
Junfeng Zhang et al.
Formononetin (FMN) is an extracted component of traditional Chinese medicine with anticancer effects, but its poor water solubility and low bioavailability have limited further research and application. Therefore, based on FMN that is the n...
Nicholas J Cormas,Kate G Johnson,Xudong Li et al.
Nicholas J Cormas et al.
Osteoarthritis (OA) is a leading cause of disability among the elderly, yet no disease-modifying therapies are available. Oxidative stress, chronic inflammation, and progressive chondrocyte degeneration remain key therapeutic targets. Conve...
Antibacterial efficacy and adaptive proteomic strategies of antibiotic-resistant pathogens on nanostructured copper surfaces [0.03%]
耐药病原体在纳米结构铜表面的抗菌功效及适应性蛋白质组策略
Blessing Hammer,Kidon Sung,Miseon Park et al.
Blessing Hammer et al.
Aims: To evaluate the antibacterial activity of nanostructured copper oxide surfaces synthesized by hot water treatment (HWT) and to elucidate the underlying mechanisms of copper-induced stress responses in antibiotic-res...
Advancements in nanotrap technology for the prevention, diagnosis and treatment of infectious diseases [0.03%]
纳米陷阱技术在防治传染病领域的研究进展
Samuel Keefer,Ana C Lorenzo-Leal,Horacio Bach
Samuel Keefer
Nanotraps are particles designed to capture and concentrate target molecules and have numerous applications in infectious diseases. This review outlines how nanotrap technologies may improve the detection and treatment of bacterial and vira...
The role of immunomodulatory nano systems in the treatment of sepsis: past, present, and future [0.03%]
免疫纳米系统在治疗脓毒症中的作用：过去、现在和未来
Md Shanewaz Hossan,Hadil A Gadelrab,Minghao Luo et al.
Md Shanewaz Hossan et al.
Sepsis is a life-threatening condition caused by a dysregulated host response to infection and remains a leading cause of death in intensive care units. Although antimicrobials and supportive care are vital, patient outcomes are hindered by...
Functionalized framework nucleic acids for the treatment of infectious diseases [0.03%]
用于治疗传染病的功能化框架核酸
Yuanlin Tang,Yunfeng Lin,Mi Zhou
Yuanlin Tang
Infectious diseases remain a major threat to global public health, a challenge further exacerbated by the rapid rise of antimicrobial resistance. In this context, tetrahedral framework nucleic acids (tFNA) have recently gained attention as ...
SuJin Hwang,Hyejun Ko,Hee-Young Lee et al.
SuJin Hwang et al.
The clustered regularly interspaced short palindromic repeat/associated protein 9 (CRISPR/Cas9) system has been used for the precise manipulation of target DNA, making efficient genome editing in cells a reality. The CRISPR/Cas9 system has ...
New insights into the mechanisms of cellular interactions and toxicity of nanomaterials [0.03%]
纳米材料细胞相互作用及毒性机制的新认识
Helmut Spielvogel,Rainer Tietze,Stefan Lyer et al.
Helmut Spielvogel et al.
Whenever nanomaterials come into contact with cells and tissues, the risk of material-specific cytotoxic reaction is increased. With the widespread use of nanoparticles in industrial, but also biomedical applications, the increasing exposur...
Nanotherapeutic strategies for fibroblast targeted treatment of pulmonary fibrosis [0.03%]
针对成纤维细胞的纳米治疗策略用于肺纤维化治疗
Richard S Nho,Rachel S Knipe
Richard S Nho
Engineering next-generation therapeutics with antibody-mimetic 'plug & play' molecular assembly technology [0.03%]
利用抗体模拟的“即插即用”分子组装技术工程化下一代药物疗法
Yujie Sheng,Kourosh H Ebrahimi
Yujie Sheng