Targeting the transferrin receptor in breast cancer: nanotechnology-based drug delivery strategies [0.03%]
基于纳米技术的药物输送策略在乳腺癌中靶向转铁蛋白受体
Zhendi Song,Chunlei Song,Xiaoli Yi et al.
Zhendi Song et al.
Breast cancer remains a leading cause of cancer-related morbidity and mortality worldwide, with treatment efficacy often limited by systemic toxicity, poor tumor selectivity, and multidrug resistance. Nanotechnology-based drug delivery syst...
Targeted nano delivery of p53 DNA and carvedilol for the treatment of dilated cardiomyopathy in a rat model [0.03%]
用于治疗扩张型心肌病的p53基因和卡维地洛纳米靶向递送小鼠模型研究
Neha Tomar,Aruna Tara Vennela,Satyajit Mukhopadhyay et al.
Neha Tomar et al.
Background: Dilated cardiomyopathy (DCM) is a major contributor to cardiovascular morbidity and mortality, and current therapies lack myocardial specificity, leading to limited efficacy and systemic toxicity. This study e...
Protein-based nanoparticles in the treatment of respiratory infectious diseases: current progress and future directions [0.03%]
基于蛋白质的纳米颗粒在呼吸道传染病治疗中的研究进展与未来方向
Pamela Kadare,Mellisa T R Chikukwa,Marique Aucamp et al.
Pamela Kadare et al.
The increasing burden of infections, heightened by the emergence of drug-resistant pathogens, emphasizes the urgent need for innovative drug delivery systems (DDS) which enhance therapeutic efficacy. Protein-based nanoparticles (NPs) from b...
Shruti Dharmaraj,Kathryn S Robinett,Achsah D Keegan et al.
Shruti Dharmaraj et al.
Allergic diseases affect an estimated 260 million people worldwide and develop due to dysregulated immune responses against harmless environmental antigens caused by a breakdown in immune tolerance mechanisms. Current standard-of-care treat...
Potential healthcare applications of metal carbonate nanoparticles produced from emerging carbon capture technologies [0.03%]
新兴碳捕获技术产生的金属碳酸盐纳米颗粒在医疗保健领域的潜在应用
Kñeisha McDonald,Deepak K Khajuria,Bingyun Li
Kñeisha McDonald
Ahmad Ziada,Cuiyan Xin,Ahmed O Elzoghby
Ahmad Ziada
Fibrotic disorders represent a worldwide health concern, leading to progressive dysfunction across multiple organs such as lung, liver, kidney, and heart. Fibrosis occurs due to persistent inflammation, coupled with differentiation of fibro...
Multifunctional plasmonic gold nanoisland films for enhanced cell theranostics through photothermal therapy and surface-enhanced Raman scattering detection [0.03%]
用于光热治疗和表面增强拉曼检测的等离激元金纳米岛薄膜细胞诊疗
Yong-Yin Yang,Chun-You Chen,Sadang Husain et al.
Yong-Yin Yang et al.
Aim: Plasmonic gold nanomaterials have numerous applications in biomedical therapy and sensing. In this work, plasmonic gold nanoisland films (AuNIFs) were demonstrated to have significant applications in photothermal the...
Thermogelation of polymer nanoassemblies: promising platforms for injectable biomaterials in medical applications [0.03%]
聚合物纳米组件的热凝胶化：可注射生物材料在医学应用中的前景平台
Binru Han,André J van der Vlies,Urara Hasegawa
Binru Han
Thermally induced gelling systems, or thermogels, represent an important class of injectable biomaterials that remain liquid prior to administration but undergo a sol - gel transition upon heating to body temperature, thereby providing a mi...
Roles and applications of peptide nucleic acid-loaded nanoparticles in cancer [0.03%]
载肽核酸纳米颗粒在癌症中的作用和应用
Natasha Shah,Suganthi Vedanayagam,Smith Raymonde et al.
Natasha Shah et al.
Peptide nucleic acid (PNA) is a neutral analogue of DNA/RNA used for diverse antisense and antigene applications. PNA exhibits excellent binding affinity, sequence specificity, resistance to enzymatic degradation, and minimal electrostatic ...
Targeting drug resistance in colorectal cancer using peptide-based scaffolds: new frontiers in colorectal cancer therapy [0.03%]
基于肽的支架靶向药物抵抗结直肠癌治疗的新前沿
Sanjukta Sen,Sreemoyee Mitra,Dipanjan Karati
Sanjukta Sen
A formidable clinical challenge, colorectal cancer (CRC) has faced a considerable limitation arising in the form of drug resistance, which in turn has affected the optimum outcome of standard chemotherapy, target therapy, and immunotherapie...