Engineering polystyrene microtube-embedded composite hydrogels for tunable vascular morphogenesis [0.03%]
工程化聚苯乙烯微管嵌入式复合水凝胶以实现可调血管发生
Xianyang Li,Sadia Khan,Liyuan Wang et al.
Xianyang Li et al.
Establishing functional vascular systems within 3D tissue constructs is crucial for their successful use in disease modeling, drug testing, and regenerative medicine. Current methods face challenges in creating small- to medium-sized microv...
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for Myocardial Infarction Therapy [0.03%]
低强度脉冲超声作为促进脂肪源干细胞分泌外泌体及其摄取治疗心肌梗死的策略
Riyue Jiang,Hao Wang,Fanglu Zhong et al.
Riyue Jiang et al.
Acute myocardial infarction (AMI) remains a major global health issue, with limited therapeutic strategies to repair damaged myocardial tissue and improve long-term cardiac function. Exosome-based therapies, particularly those derived from ...
Fine-tuning equilibrium water content and mechanical properties of acrylic-based copolymers for intraocular lens applications [0.03%]
用于人工晶状体的丙烯酸基共聚物的平衡水分和机械性能的精细调节
Deniz Aki,Monireh Esmaeili Rad,Esat Can Şenel et al.
Deniz Aki et al.
We report on the development of copolymers of 2-Hydroxy Ethyl Acrylate (HEA) with 2-(2-Ethoxy Ethoxy) Ethyl Acrylate (EEEA) grafted with Ethylene Glycol Di-Methacrylate (EGDMA), designed for use as an intraocular lens (IOL) material. Variou...
Auxiliary Electrode Tunes Wet-Electrospun Bundle Stiffness to Modulate Cell Phenotype [0.03%]
辅助电极调节湿法电纺纱束刚度以调节细胞表型
Haoyu Wang,Chelsea Violita Stanley,Xiangshen Gao et al.
Haoyu Wang et al.
The stiffness of tissue-engineered scaffolds significantly influences cell behaviour and phenotype. However, current approaches to tuning stiffness often introduce unintended variations and compromise topographical consistency. In this stud...
Exosome as a stable carrier for anti-inflammatory phenylpropanoid metabolites: a proof-of-concept study [0.03%]
外泌体作为抗炎酚类代谢产物的稳定载体：概念验证研究
Shirali Patel,Neeraja Revi,Suridh Chakravarty et al.
Shirali Patel et al.
Phenylpropanoids (PA), which are plentiful in cruciferous vegetables, have not received adequate attention for their anti-inflammatory properties. Despite their potential benefits, the bioavailability and stability of these and other natura...
Aloe vera-enriched collagen-polyurethane hydrogel: Supporting tissue regeneration, antibacterial action and drug release for effective wound healing [0.03%]
富含 aloevera 的胶原-聚氨酯水凝胶：支持组织再生，抗菌作用及药物释放以实现有效伤口愈合
Maria I León-Campos,Jesús A Claudio-Rizo,Juan J Becerra-Rodriguez et al.
Maria I León-Campos et al.
Aloe vera is widely recognized for its healing, anti-inflammatory, moisturizing, and antibacterial properties, which are attributed to its rich biochemical composition, including polysaccharides, proteins, vitamins, and anthraquinones such ...
Bio-design material as scaffold module proposed to surgical application in osteoarthritis: fabrication, characterization, biological evaluation of in vitro testing [0.03%]
用于骨关节炎手术应用的生物设计材料作为支架模块的研究：体外测试的制备、特征分析和生物学评价
Atsadaporn Thangprasert,Anne Bernhardt,Elke Gossla et al.
Atsadaporn Thangprasert et al.
Treatment of osteochondral defects is a major topic of current research and becomes more important in an aging society. The challenges in bone and cartilage repair arise from structure and function of these different tissues. This study pro...
Spinal Fusion Properties of Mechanically-Reinforced, Osteomodulatory Chitosan Hydrogels [0.03%]
机械增强型和促进骨生长的壳聚糖水凝胶的脊柱融合性能
Blake T Darkow,August J J Hemmerla,Joseph P Herbert et al.
Blake T Darkow et al.
Lower back pain is a considerable medical problem that will impact 80% of the U.S. population at some point in their lifetime. For the most severe cases, surgical repair is necessary and is associated with annual costs upwards of $10 billio...
Fabrication and in vivo characterization of FRESH-based 3D printed chitosan construct for small intestine regeneration [0.03%]
基于FRESH的三维打印壳聚糖构造物的小肠组织再生研究及体内评价
Parul Chaurasia,Richa Singh,Rishabh Rai Kaushik et al.
Parul Chaurasia et al.
This study demonstrates the implantation of a 3D-printed small intestine construct using chitosan bioink and freeform reversible embedding of suspended hydrogels (FRESH) bioprinting technology. The research addresses the significant clinica...
Hydroxyapatite-induced bioactive and cell-imprinted polydimethylsiloxane surface to accelerate osteoblast proliferation and differentiation: an in vitro study on preparation and differentiating capacity [0.03%]
一种加速成骨细胞增殖和分化的羟基磷灰石诱导的生物活性及印迹聚二甲基硅氧烷表面的体外研究：制备方法与分化潜能
Morteza Mehrjoo,Akbar Karkhaneh,Masoumeh Haghbin Nazarpak et al.
Morteza Mehrjoo et al.
Healing bone defects remains a significant orthopedic challenge. Cell therapy and tissue engineering offer promising solutions; however, obtaining high-quality, partially or fully differentiated cells remains difficult. Therefore, developin...