Tumor-responsive nanomedicines for cancer therapy: design principles and therapeutic advances [0.03%]
基于肿瘤响应的癌症治疗纳米药物:设计原则和治疗进展
Yan Liu,Yinan Wang,Ahequeli Gemingnuer et al.
Yan Liu et al.
Tumor microenvironment (TME)-responsive nanomedicines have emerged as a promising precision therapeutic strategy in cancer treatment. By incorporating stimuli-responsive properties, these nanomedicines can achieve targeted delivery and cont...
Inorganic whiskers containing Alkaline and Bioactive Ions enhance the comprehensive properties of 3D-printed Biopolymer Bone Scaffold [0.03%]
含碱性及生物活性离子的无机 whiskers 改善了基于天然高分子的三维打印骨支架的综合性能
Sidan Feng,Bowen Li,Yanting Wei et al.
Sidan Feng et al.
Polylactic acid (PLA) has been widely studied as a scaffold material for bone tissue engineering but still faces challenges such as insufficient mechanical strength, slow degradation rate, and poor biomineralization and cellular response. I...
SERS based pH nanosensors for in-vitro pH measurement in multicellular 3D Tumour spheroids [0.03%]
用于多细胞三维肿瘤球体的体外pH测量的SERS-based pH纳米传感器
Koyel Dey,Venkanagouda S Goudar,Tuhin S Santra et al.
Koyel Dey et al.
Tumor acidosis is a consequence of altered metabolism that, primarily takes place due to lactate secretion from anaerobic glycolysis. As a result, many regions within the tumors are chronically hypoxic and acidic. Here, we have fabricated a...
The enhanced osteogenesis of calcium phosphate oligomers modified collagen membrane to guide bone regeneration [0.03%]
一种钙磷寡聚体改性胶原膜的促骨生成作用及其引导组织再生性能的研究
Xiaoying Xu,Jiuzhou Dong,Hongkun Chen et al.
Xiaoying Xu et al.
Guided bone regeneration (GBR) is a promising technology for enhancing osteogenesis while preventing the invasion of fibrous tissue in implantation. Although collagen membranes have been widely utilized in GBR applications, their ability to...
Maximising adherent cell production via customisable and dissolvable bio-polymer microcarriers [0.03%]
一种可定制和溶解的生物聚合物微载体用于最大化贴壁细胞生产
Timothy R Cox,David Lesmana,Christopher J OKeeffe et al.
Timothy R Cox et al.
Large-scale cellular production systems offer a significant and diverse benefit impacting the therapeutic (stem cell and vaccine production) and cellular agriculture (lab-grown meat) sectors. Producing desired cells at mass can improve prod...
Enhance osteogenesis of BCP bioceramics by autocrine induced membrane to bone regeneration [0.03%]
自分泌诱导膜促进BCP生物陶瓷骨再生及成骨研究
Xiaohua Wang,Yuehao Wu,Aiai Li et al.
Xiaohua Wang et al.

This study investigates a novel strategy combining biphasic calcium phosphate (BCP) bioceramics with autocrine induced membranes to enhance osteogenesis and vascularization for bone regeneration.
Methods:
Highly bioactive, poro...
Poly (ortho esters) (POEs) as cutting-edge biodegradable polymers for targeted cancer treatment and overcoming multidrug resistance [0.03%]
聚(正交酯)(POE)作为针对癌症治疗和克服多药耐药性的新一代可生物降解聚合物
Devansh Shah,Sankha Bhattacharya
Devansh Shah
Poly (ortho esters) (POEs), biodegradable polymers featuring acid-labile ortho ester bonds formed through diol-diketene acetal reactions, are transforming cancer treatment with pH-sensitive surface erosion. This analysis explores the develo...
A brief overview of hyaluronic acid research and its applications in cell culture [0.03%]
透明质酸的研究概况及其在细胞培养中的应用展望
Huanyu Zhu,Na Zhao,Xueping Guo
Huanyu Zhu
Background
Hyaluronic acid (HA) is a large molecular acidic glycosaminoglycan that is widely present in the extracellular matrix of cells. Aside from being an important component of the extracellular matrix, HA is an excellent biomateri...
Hepatocellular carcinoma-derived protein encapsulated iron oxide/black phosphorus nanosheets for targeted photothermal-chemotherapy [0.03%]
肝细胞癌衍生蛋白包封的铁氧化物/黑磷纳米片用于靶向光热化学治疗
Danhong Yan,Chaiqiong Guo,Yang Wang et al.
Danhong Yan et al.
In cancer treatment, single modalities such as chemotherapy or photothermal therapy (PTT) often face significant limitations, leading to suboptimal therapeutic outcomes. In recent years, the combination of chemotherapy and PTT has garnered ...
Melis Toker Bayraktar,Bora Garipcan,Stephen D Waldman
Melis Toker Bayraktar
Cartilage is a load-bearing connective tissue with limited self-healing capacity and tissue engineering approaches aim to develop functional scaffolds for the repair and regeneration of damaged cartilage. Scaffold porosity and mechanical ch...