Dual-engineered small extracellular vesicles targeted delivery miR-126 for reducing age-related bone loss [0.03%]
双功能修饰外泌体递送miR-126促进防治骨质疏松
Junming Tao,Ruiyu Du,Yi Zhang et al.
Junming Tao et al.
MiRNA based nucleic acid therapeutics have been extensively investigated for the treatment of agerelated diseases. However, efficient delivery of miRNA and effective therapy for age-related bone loss remain major challenges. In this study, ...
Electrospun PCL/PEG nanofibers incorporating Plantago lanceolata extract and clove oil for dual-function wound dressings [0.03%]
掺入鼠耳草提取物和丁香油的PCL/PEG电纺纳米纤维用于双功能伤口敷料
Selin Nur Teke,Adile Yuruk,İsmail Alper İşoğlu
Selin Nur Teke
In this study, we developed electrospun polycaprolactone/polyethylene glycol (PCL/PEG) nanofibers loaded withPlantago lanceolata (P. lanceolata)extract and clove oil to evaluate their combined potential for wound healing and antibacterial a...
Biomimetic catalase-engineered black phosphorus nanosheets enhance photo-/radio-therapy for hepatocellular carcinoma [0.03%]
类酶催化的黑磷纳米片增强光动力/放射治疗用于肝细胞癌治疗
Chunzhong Qiao,Qiucheng Lei,Liangqi Lu et al.
Chunzhong Qiao et al.
The hypoxic tumor microenvironment (TME) critically impairs the therapeutic efficacy of photo- and radiotherapy (RT) in hepatocellular carcinoma (HCC). Ameliorating tumor hypoxia thus presents a promising strategy to potentiate these treatm...
Self-lubricating anticoagulant surface (SLACS) mimicking heart valve tissue for improving biocompatibility of artificial blood pumps [0.03%]
模拟心瓣膜组织的自润滑抗凝表面(SLACS)，以提高人造血泵的生物相容性
Shiyu Cui,Yaoyao Chen,Jun Zhong et al.
Shiyu Cui et al.
Extracellcular membrane oxygenation (ECMO) is the most advanced form of extracorporeal life support. Its centrifugal pump head, a key component in contact with blood, requires excellent blood compatibility for optimal performance. To addres...
A mechanically interlocked bilayered small-diameter vascular graft with SilMA-PVA hydrogel and biaxially expanded polytetrafluoroethylene for promoting cytocompatibility [0.03%]
一种机械互锁的双层小直径血管移植物，用于促进细胞相容性，该移植物结合了SilMA-PVA水凝胶和双向拉伸聚四氟乙烯
Changlong Deng,Shujie Yan,Xiaofeng Wang et al.
Changlong Deng et al.
Conventional PTFE tubes only expand axially and exhibit low radial strength and poor elasticity, which limits their clinical translation in small-diameter vascular grafts. In this study, biaxial stretching was employed to endow the ePTFE tu...
Boosting the mechanical and biological performance of decellularized plant-derived scaffolds via alkali-mediated mercerization [0.03%]
通过碱介导的 Mercer 处理提高植物衍生脱细胞支架的机械和生物性能
Sezin Aliye Bozdoğan,Merve Ünal,Serkan Dikici
Sezin Aliye Bozdoğan
Tissue engineering aims to develop functional biomimetic constructs to restore, maintain, or replace damaged tissues. Recently, decellularized plant-based scaffolds have emerged as sustainable, cost-effective, and ethically favorable altern...
Design and fabrication of a 3D printed auxetic - electrospun scaffold for tendon structure modelling [0.03%]
一种用于肌腱结构建模的3D打印斜纹-电纺支架的设计与制造
Giacomo Cortella,Alessandro Velletri,Erwin Pavel Lamparelli et al.
Giacomo Cortella et al.
Tendon tissue engineering requires scaffolds with an appropriate structure that can be cultured under cyclic strain in order to replicate both mechanical cues and biological commitments. This study presents a hybrid scaffold combining 3D-pr...
A scalable and cost-effective 3D tumor spheroid array chip for distortion-free optical monitoring and drug screening [0.03%]
一种可扩展且成本效益高的三维肿瘤球囊阵列芯片，用于无畸变光学监测和药物筛选
Yang Lu,Haoran Chen,Xiaoying Yin et al.
Yang Lu et al.
This study presents a novel, cost-effective, and transparent tumor spheroid array chip fabricated via Mask Stereolithography (MSLA) 3D printing and Polydimethylsiloxane (PDMS) molding, enabling the scalable generation of thousands of unifor...
Mechanistic study on hyaluronic acid polysiloxane gel promoting wound repair guided by wet healing theory [0.03%]
基于湿性愈合理论的透明质酸聚硅氧烷凝胶促伤口修复作用机制研究
Weichang Shen,Chen Cao,Zhihan Zhu et al.
Weichang Shen et al.
As a vital barrier organ of the human body, skin wound repair faces clinical challenges such as slow healing, scar hyperplasia, and infection. Although the wet healing theory has confirmed that a moist environment can enhance epidermal cell...
3D-printed β-TCP scaffolds coated with palmarosa essential oil: Antibacterial and cytotoxicity studies [0.03%]
3D打印β-TCP载油醇挥发油支架的抗菌及细胞毒性研究
Verônica Ribeiro Dos Santos Borges,Marcia Cristina Bezerra Melo,Lilian de Siqueira et al.
Verônica Ribeiro Dos Santos Borges et al.
The use of natural antibacterial agents in bone tissue engineering has gained attention as an alternative to conventional antibiotics, particularly in response to the growing challenge of bacterial resistance. In this study, β-tricalcium p...