TAPP@NBs combined with GSNO to enhance the anti-liver cancer effect of sonodynamic therapy [0.03%]
基于GSNO和TAPP@NBs的协同增效策略强化SDT抗肝癌效应
Chunyue Wang,Wang Xiaodong,Fengjiao Chen et al.
Chunyue Wang et al.
Due to its significant tissue penetration, sonodynamic therapy (SDT) is rapidly becoming a viable alternative to traditional photodynamic therapy. However, the therapeutic efficacy of a single SDT treatment is constrained by the prolonged h...
Stem cell membrane-coated rough mesoporous silica nanoparticles for enhanced osteogenic differentiation and bone repair via dexamethasone delivery [0.03%]
负载糖皮质激素的间充质干细胞膜涂层不规则介孔硅纳米颗粒用于促进成骨分化及骨修复
Peng Chen,Jiawei Lu,Yi Liu et al.
Peng Chen et al.
Mesoporous silica nanoparticles (MSNs) have been demonstrated to promote osteoblast differentiation; however, the unclear impact of their surface roughness on osteogenesis, coupled with inadequate targeting capability and suboptimal therape...
Inorganic polyphosphate, a paradigm changer in 3D printing of β-tricalcium phosphate based materials for bone tissue surgery [0.03%]
无机多聚磷酸盐在β-三钙磷灰石基材料的三维打印技术中的应用及其在骨组织手术修复中的作用研究
Meik Neufurth,David Molter,Xiaoqing La et al.
Meik Neufurth et al.
β-Tricalcium phosphate (β-TCP) is widely used as a material for bone implants due to its excellent biocompatibility, biodegradability, and osteoconductivity, as well as its osteoinductive properties. Here, we demonstrate that the regenera...
Biocompatible Hydrogel Microspheres Based on Modified Silk Fibroin and Gelatin for Injectable 3D Bone Tissue Scaffolds [0.03%]
一种用于注射式骨组织工程支架的生物相容性水凝胶微球体，基于改性的丝素和明胶
Changsheng Lu,Runqing Shen,Xiao Wang
Changsheng Lu
Currently investigated two-dimensional cell culture systems are typically inadequate for large-scale cell expansion and prone to causing altered cell morphology, aberrant differentiation, and distorted protein expression. To overcome these ...
ROS-driven, p53-mediated apoptosis in HepG2 cells induced by Blumea eriantha carbon quantum dots [0.03%]
利用白花丹碳量子点诱导HepG2细胞中ROS介导的p53凋亡通路
Pallavi Laxman Salve,Somnath Devidas Bhinge
Pallavi Laxman Salve
Carbon quantum dots (CQDs), owing to their small size, special surface functionalities, and remarkable fluorescence properties, have gained significant attention from researchers in the biomedical field. In the present work, CQDs were synth...
Antimicrobial self-healing injectable hydrogels based on chitosan, collagen, and polyvinyl alcohol for chronic wound treatment [0.03%]
基于壳聚糖、胶原蛋白和聚乙烯醇的抗菌自修复注射型水凝胶用于慢性伤口治疗
Lorena Duarte-Peña,Sheila Iraís Peña-Corona,Luis Esaú López-Jácome et al.
Lorena Duarte-Peña et al.
Chronic wounds stand as a significant challenge to public health due to their high prevalence and complications, such as difficult-to-treat infections. The present study focuses on developing antimicrobial self-healing injectable hydrogels ...
pH controlled release of extracellular vesicles from a hydrogel scaffold for therapeutic applications [0.03%]
用于药物治疗的基于pH响应性水凝胶载体制备外泌体及其释放行为研究
Simon Chewchuk,Nicholas Soucy,Fan Wan et al.
Simon Chewchuk et al.
Cell-based therapies are gaining attention as a promising approach for repairing damaged tissues and organs, offering alternatives to invasive treatments like organ transplants and powerful medications. Recent research has shifted towards e...
Bilayer oxidized sodium alginate-carboxymethyl chitosan hydrogel microspheres enable sustained BMP-2 release for enhanced bone regeneration [0.03%]
双层氧化海藻酸盐-羧甲基壳聚糖水凝胶微球实现骨形态发生蛋白-2的持续释放并促进成骨修复
Yafei Yuan,Xige Zhao,Jiangqi Hu et al.
Yafei Yuan et al.
Bone morphogenetic protein-2 (BMP-2) is a highly potent osteoinductive factor that has received approval from the U.S. Food and Drug Administration (FDA) due to its significant osteogenic properties. Nonetheless, its clinical utility is lim...
Shortwave Infrared Imaging-Guided Radiosensitization using Rare-Earth-Doped Nanoparticles delivered via Microneedles for enhanced Melanoma therapy [0.03%]
利用微针递送稀土掺杂纳米颗粒进行近红外光引导的增敏 radiosensitization用于增强黑色素瘤治疗
Mohd Yaqub Khan,Jen-Kun Chen,Lokesh Agrawal et al.
Mohd Yaqub Khan et al.
Melanoma remains a major global health challenge due to the uncontrolled growth of abnormal skin cells, resistance to conventional therapies, and poor prognosis in advanced cases. Localized, early-stage melanoma, defined as melanoma confine...
Characterizing Spatiotemporal Microbial Colony Distributions in Printed PEG-DA Hydrogel Films [0.03%]
表征印刷PEG-DA水凝胶薄膜中时空微生物菌落分布特性
Isaak Thornton,Kathryn Zimlich,Matthew W Fields et al.
Isaak Thornton et al.
Biofilms are surface-attached microbial communities that play vital roles in natural ecosystems and contribute to persistent problems in medicine and industry. These communities exhibit heterogeneous chemical, physical, and physiological pr...