Construction of a chromium doped zinc gallate composite nano drug loading platform for enhancing anti-tumor efficacy through the combination of chemotherapy and photothermal therapy [0.03%]
构建掺铬锌镓氧化物复合纳米药物递送平台通过化学疗法和光热疗结合增强抗肿瘤功效
Yan Liu,Jiahui Chen,Fang Li et al.
Yan Liu et al.
In recent years, nanoparticles have become key carriers for cancer diagnosis and therapy. In this study, chromium-doped zinc gallium oxide nanomaterials (ZnGa2O4:Cr3+, ZGC) with uniform morphology were synthesized via a one-step hydrotherma...
Bioactive UiO-66 coating on polydopamine-modified titanium implants [0.03%]
聚多巴胺改性钛种植体上的生物活性UiO-66涂层
Aslı Ece Gümüşkaya,Berna Topuz,Sezin Galioglu et al.
Aslı Ece Gümüşkaya et al.
Engineering the surface of titanium (Ti) with bioactive coatings is an effective approach to address biofunctional limitations of Ti implants, including low bioactivity and poor tissue integration. Here, Ti substrates were functionalized wi...
Bio-functional porous PLA microspheres: an in-vitro study of a platform for plasma rich in growth factors (PRGF) delivery [0.03%]
具有生物功能的多孔PLA微球：体外研究富生长因子血浆（PRGF）递送平台
MohammadHossein Shah-Mohammadi-Loshani,Rana Imani,Mahdi Khalili
MohammadHossein Shah-Mohammadi-Loshani
Effective management of acute and chronic wounds remains a major clinical challenge, driving the need for innovative therapeutic approaches. Plasma rich in growth factors (PRGF), an autologous and bioactive fraction of platelet-rich plasma,...
Syringeable hyaluronic acid-based hydrogel co-loaded with Cisplatin and MSA-2 for enhanced ovarian cancer chemoimmunotherapy [0.03%]
一种新型透明质酸基水凝胶联合递送顺铂和MSA-2用于增强卵巢癌的化免疫联合治疗
Zhengfei Sun,Dehua Wei,Guofeng Ji
Zhengfei Sun
Low immunogenicity and a prevailing immunosuppressive tumor microenvironment (TME) remain major bottlenecks for ovarian cancer immunotherapy. While plati-num-based chemotherapy can trigger antitumor immunity via immunogenic cell death (ICD)...
Evaluation of bioactive scaffold magnesium-containing hydroxyapatite from biomass resources for supporting osteogenesis, angiogenesis, and in vivo bone regeneration [0.03%]
基于生物质资源的生物活性镁掺杂羟基磷灰石支架的评价及其对成骨、血管生成和体内骨再生的支持作用研究
I Kadek Hariscandra Dinatha,Endang Haryati,Jumiarti A Lolo et al.
I Kadek Hariscandra Dinatha et al.
Translating artificial bone research into clinical applications requires numerous preclinical studies to evaluate the bioactivity of scaffolds in facilitating cell adhesion, proliferation, osteoblastic differentiation, and angiogenic differ...
Utilizing biological responses to evaluate the In vivo fate and biocompatibility of reduced graphene oxide-integrated nerve guidance conduits for peripheral nerve repair [0.03%]
利用生物反应评估还原型石墨烯氧化物集成神经导管的体内命运与生物相容性以修复外周神经损伤
Jingyun/ Xi,Xiaojing Li,Qi Guo et al.
Jingyun/ Xi et al.
Reduced graphene oxide (rGO) has been widely incorporated into nerve guidance conduits (NGCs) to promote peripheral nerve regeneration owing to its physicochemical properties. However, some studies have reported potential biocompatibility r...
An in vitro study of osteogenic and antibacterial properties of ZnO-BaTiO 3 coated titanium [0.03%]
一种具有成骨和抗菌性能的ZnO-BaTiO₃涂层钛材料的体外研究
Yujie Tao,Tingyu Xu,Yilai Jiao et al.
Yujie Tao et al.
The research and development of artificial bone materials has become the focus of clinical bone tissue engineering research. Currently, surface modification is often used to give titanium excellent bone regeneration ability and antibacteria...
Dihydromyricetin enhances the anti-calcification performance of glutaraldehyde-cross-linked bovine pericardial valve materials by stabilizing elastin [0.03%]
二氢杨梅素通过稳定弹性蛋白来增强戊二醛交联的牛心包瓣膜材料的抗钙化性能
Zhenlin Jiang,Yan Hu,Junting Chen et al.
Zhenlin Jiang et al.
At present, most biological valves used for clinical application are created using glutaraldehyde (GLUT) cross-linked animal pericardia or aortic valve materials. Since GLUT cannot cross-link with elastin, which would be further degraded an...
Anisotropic tissue biofabrication: conventional and advanced fabrication strategies for functional scaffolds [0.03%]
各向异性组织生物制造：功能性支架的常规和先进制备策略
Masoud Shirzad,Omid Kordi,Dasong Kim et al.
Masoud Shirzad et al.
Natural tissues possess structurally organized architectures that enable specialized mechanical and functional behaviors. Anisotropy, defined as the directional dependence of material properties, is a key characteristic observed across a wi...
Youthful-state extracellular vesicles for targeted therapy of intervertebral disc degeneration: resolving inflammation and pyroptosis through NF- κ B suppression and NLRP1 inactivation [0.03%]
年轻状态的细胞外囊泡靶向治疗椎间盘退变：通过抑制NF-κB和失活NLRP1来缓解炎症和pyroptosis
Zhiwei Liao,Kun Wang,Ming Lei et al.
Zhiwei Liao et al.
Intervertebral disc degeneration pathogenesis involves chronic inflammation and cell death, highlighting the need for targeted therapeutic strategies. Extracellular vesicles (EVs) have emerged as promising bioactive materials for designing ...