Comparative study of the bioactive PLGA/CaP composites: the influence of 3D structure on inflammatory and osteoinductive properties [0.03%]
生物活性PLGA/CaP复合材料的比较研究：三维结构对炎性和成骨诱导性能的影响
Andrei V Yushkov,Ekaterina A Kuvshinova,Inna N Bulygina et al.
Andrei V Yushkov et al.
We aimed to develop a composite poly(lactic-co-glycolic acid) (PLGA)/calcium phosphate nanoparticles scaffold with the optimal three-dimensional structure to provide an environment for bone tissue regeneration. Composite PLGA-based scaffold...
Selective laser melting of CoCrMo-Ti6Al4V bimetallic composites: fabrication, characterization, and cytocompatibility [0.03%]
选择性激光融化制备CoCrMo-Ti6Al4V双金属复合材料：制备、表征及细胞相容性评估
SiJing Lin,Tiantian Gao,Sung-Min Chung et al.
SiJing Lin et al.
Bimetallic structures integrating Ti6Al4V and CoCrMo alloys present a promising solution for advanced orthopedic implants by combining high fracture toughness with excellent wear resistance. However, the direct fabrication of these dissimil...
Acoustic droplet ejection enables the transfer of induced pluripotent stem cells in ultra-high concentrations while preserving their pluripotency [0.03%]
声学液滴打印技术能在超高压条件下转移诱导多能干细胞并保持其多能性
Alejandro Gómez Montoya,Leon Ryu Breulmann,Reyyan Güzide Tağman et al.
Alejandro Gómez Montoya et al.
Acoustic droplet ejection (ADE) has been widely used for the precise transfer of liquids, hydrogels, and cell suspensions in different applications. One interesting advantage of this technique is its nozzle-less nature, allowing for low-she...
In situ synthesized silver nanoparticle-loaded poly(vinyl alcohol)/gelatin composite films for burn wound dressing applications: antibacterial activity and in vivo wound-healing evaluation [0.03%]
用于烧伤伤口敷料的聚乙烯醇/明胶复合膜负载的原位合成银纳米颗粒：抗菌活性及在体促伤口愈合评价
Zehra Gün Gök,Beste Çağdaş Tunalı,Yaşar Şahin et al.
Zehra Gün Gök et al.
This study aimed to develop and evaluate poly(vinyl alcohol)/gelatin (PVA/Gel/AgNPs) composite films containing silver nanoparticles (AgNPs), which have the potential to be used as burn wound dressings. In the present study, AgNPs at differ...
Porous scaffolds for vascularized bone regeneration: a review of recent advances [0.03%]
用于血管化骨再生的多孔支架：近期进展综述
Xinyue Liu,Duoling Xu,Chao Wang
Xinyue Liu
Bone tissue defects, which are frequently caused by tumors, infections, traumas, and developmental malformations, have been recognized as significant clinical challenges in tissue regeneration. The development of porous scaffolds that demon...
Structural, mechanical and biological evaluation of MgO and SrO modified bioglass 45S5® [0.03%]
MgO和SrO改性生物玻璃45S5®的结构、力学及生物学性能评价
Mariana Gunther Borges,Alicce Silveira Marques Reis,Paulo Soares et al.
Mariana Gunther Borges et al.
Human tissues deteriorate over time and may not regenerate naturally, motivating the development of bioactive materials capable of stimulating tissue repair. Since the discovery of Bioglass 45S5®, this material has been widely recognized a...
A dual-functional 3D scaffold with an imidazolium-based interface for non-antibiotic therapy and enhanced osseointegration in infected bone defect [0.03%]
一种基于咪唑
Zeyuan Li,Guosheng Hua,Ziqi Liu et al.
Zeyuan Li et al.
Infected bone defects pose a significant clinical challenge due to the need for prolonged antibiotic therapy and multiple bone grafting procedures, which often lead to antibiotic overuse and increased patient burden. In this study, we devel...
An LCD 3D-printed microphysiological system with deflectable extracellular matrix thin films [0.03%]
一种具有可弯曲细胞外基质薄膜的LCD 3D 打印微生理系统
Matt D Nelson,Patrick A Tresco,Amirhossein Razaghian et al.
Matt D Nelson et al.
Microphysiological systems (MPS) have emerged as promising models to better recapitulate in vivo microenvironments, but they often rely on manufacturing techniques that limit their scalability and constrain non-trivial three-dimensional arc...
Multifunctional injectable BLGFs/ODEX/COL hydrogel With sustained localized phage release for concurrent antimicrobial activity and bone tissue regeneration [0.03%]
一种用于同时抗菌和骨组织再生的长效局部释放BLGFs/ODEX/COL多功能注射水凝胶
Bhahat Lawlley Zimba,Xiaohan Yang,Elingarami Sauli et al.
Bhahat Lawlley Zimba et al.
Bone tissue has an inherent capacity for regeneration; however, this process is significantly impaired when the bone defects is large and infected by bacteria, particularly with multidrug-resistant strains. In this study, an injectable β-l...
Cell-based bioactive materials for osteoarthritis therapy: a comprehensive review [0.03%]
细胞来源的用于骨关节炎治疗的生物活性材料：综述
Qing-Jun Liang,Shi Cheng,Bo-Rui Qiao
Qing-Jun Liang
Osteoarthritis (OA) is multifactorial degenerative joint diseases with high incidence and heavy burden on human health and the world economy. Conventional approaches to combat OA have certain therapeutic efficacy. However, these treatments ...