Enhancing wound healing: Incorporating carotenoid pigments from kocuria sp. bacteria in alginate/chitosan/PVA dressing [0.03%]
一种藻酸盐/壳聚糖/PVA敷料,兼具科氏色酮菌类胡萝卜素色素的伤口护理和美容功效以促进伤口愈合
Morteza Karimian Dorhoni,Norolhoda Khalighi,Somayeh Reiisi et al.
Morteza Karimian Dorhoni et al.
Certain wounds do not heal spontaneously and require external interventions to facilitate the healing process. Among these interventions, wound dressings play a crucial role. Biocomposite dressings, which integrate properties such as antiox...
Engineering intervertebral disc replacements using 3D-printed open gyroid architectures [0.03%]
基于3D打印开放六角晶系结构的椎间盘假体研发工程学研究
Jan Mussler,Joerg Lienhard,Sunil Shetty et al.
Jan Mussler et al.
Degenerative disc disease is a leading cause of chronic back pain, and current surgical treatments such as fusion and disc arthroplasty remain limited by implant wear, stress shielding, and mechanical mismatch with the native intervertebral...
De novo periosteum formation and remodeling activity in human cortical shells versus autograft blocks: Stereological quantification of bone cells in rabbit calvarial defect models [0.03%]
人骨皮质板与自体移植块中固有骨外膜形成及重塑的再造活性:兔颅顶缺损模型中的骨细胞立体学定量分析
Soroush Talakesh,Ashraf Hassanpour-Dehnavi,Dashtizadeh Boushehri et al.
Soroush Talakesh et al.
This study aimed to characterize periosteal formation and remodeling activity by stereological quantification of osteoblasts, osteoclasts, and osteocytes in autograft blocks and human cortical shells, providing a histological basis for bone...
Development of an injectable, conductive nanocomposite hydrogel reinforced with reduced graphene oxide for potential application in electrically active tissue engineering [0.03%]
一种用于电活性组织工程的潜在应用的可注射、导电的还原氧化石墨烯纳米复合水凝胶的发展研究
Ali Mokhtarzade,Mohamad Sadegh Aghajanzadeh,Tahoura Ebrahimi-Nozari et al.
Ali Mokhtarzade et al.
The development of injectable and printable conductive hydrogels is of great importance for tissue engineering, particularly for supporting the regeneration of electrically active or excitable tissues. In this study, a nanocomposite hydroge...
Composite bone cements based on halloysite nanotube with enhanced drug elution [0.03%]
一种以高岭土纳米管为基础的骨水泥,可增强药物缓释性能
Chen Wang,Yang Xu,Hong-Liang Wang et al.
Chen Wang et al.
Antibiotic-loaded PMMA (polymethylmethacrylate) bone cement (ALBC) is widely used to prevent and treat periprosthetic joint infections (PJIs), yet its clinical efficacy is limited by issues like burst release and short release duration. To ...
Mechanically regulated differentiation of adipose-derived mesenchymal stem cells by PDA-functionalized injectable microgels towards intervertebral disc repair [0.03%]
用于治疗椎间盘损伤的PDA功能化可注射微凝胶调控脂肪来源间充质干细胞分化性能
Xianpeng Huang,Wendong Cai,Wenkang Chen et al.
Xianpeng Huang et al.
Mechanotransduction refers to the cellular mechanism by which mechanical cues from the extracellular matrix (ECM) are sensed and transduced into biochemical signals, playing a critical role in regulating stem cell differentiation. In degene...
Enhancing soft tissue regeneration with a 3D-printed Exos@GelMA+PCL biohybrid scaffold via M2 macrophage polarization [0.03%]
基于M2型巨噬细胞极化的仿生复合支架促进三维打印软组织再生
Danxi Li,Lan Hou,Zijie Meng et al.
Danxi Li et al.
Three-dimensional (3D)-printed biodegradable breast scaffolds with patient-specific shapes and tissue-specific mechanics have attracted increased attention for soft tissue reconstruction. However, it still remains a challenge for the existi...
Myoblast and ADSC coculture on conductive highly aligned nanofiber scaffolds for human skeletal muscle tissue engineering [0.03%]
导电性高取向纳米纤维支架上骨髓间充质干细胞与肌管共培养的人体骨骼肌肉组织工程学研究
Xiu Shi,Aijia Cai,Andreas Arkudas et al.
Xiu Shi et al.

Conductive materials play a crucial role in enhancing functional performance in muscle tissue engi-neering. This study investigates the impact of the conductive polymer polyaniline (PANi) in Polycapro-lactone-Collagen Type I (PCL-colla...
Surface-engineering RNA nanoparticles for targeted and efficient hepatocellular carcinoma drug delivery [0.03%]
表面工程RNA纳米颗粒用于靶向和高效肝细胞癌药物递送
Nayoung Youn,Sunghyun Moon,Iksoo Jang et al.
Nayoung Youn et al.
Chemotherapy is an anti-cancer treatment that uses chemical drugs to suppress rapidly growing cancer cells. Nevertheless, low water solubility and poor pharmacokinetics of chemotherapeutic drugs can reduce therapeutic efficacy and limit the...
Development and Characterization of Manganese Doped Hydroxyapatite Incorporated Wet-Electrospun Polycaprolactone Scaffolds [0.03%]
一种含锰的羟基磷灰石载药湿电纺丝聚己内酯支架的制备及表征研究
Alaleh Samiei,Hossein Jodati,Zafer Evis et al.
Alaleh Samiei et al.
Bioceramic incorporated polymer-based scaffolds have gained more interest as a promising effective approach in bone tissue engineering (BTE) applications. This study is the first to investigate the role of incorporated manganese-doped hydro...