Overcoming negatively charged tissue barriers: Drug delivery using cationic peptides and proteins [0.03%]
克服带负电的组织屏障：使用带正电的肽和蛋白质进行药物传递
Armin Vedadghavami,Chenzhen Zhang,Ambika G Bajpayee
Armin Vedadghavami
Negatively charged tissues are ubiquitous in the human body and are associated with a number of common diseases yet remain an outstanding challenge for targeted drug delivery. While the anionic proteoglycans are critical for tissue structur...
Stimulus-Responsive Sequential Release Systems for Drug and Gene Delivery [0.03%]
刺激响应性顺序释放体系在药物和基因递送方面的应用
Sepideh Ahmadi,Navid Rabiee,Mojtaba Bagherzadeh et al.
Sepideh Ahmadi et al.
In recent years, a range of studies have been conducted with the aim to design and characterize delivery systems that are able to release multiple therapeutic agents in controlled and programmed temporal sequences, or with spatial resolutio...
Best practice in reporting corona studies: Minimum information about Nanomaterial Biocorona Experiments (MINBE) [0.03%]
冠状研究报道的最佳实践：纳米材料生物冠实验的最少信息(MINBE)
Andrew J Chetwynd,Korin E Wheeler,Iseult Lynch
Andrew J Chetwynd
Characterisation of the adsorption of biomolecules, or a biocorona, on nanomaterials has proliferated in the past 10 years, as protein corona studies provide molecular level insight into mechanisms of cellular recognition, uptake, and toxic...
Pengyu Chen,Feng Ding,Rong Cai et al.
Pengyu Chen et al.
The protein corona has served as a central dogma and a nuisance to the applications of nanomedicine and nanobiotechnology for well over a decade. Here we introduce the emerging field of amyloidosis inhibition, which aims to understand and h...
V Palmieri,M Papi
V Palmieri
The pneumonia outbreak of coronavirus disease 2019 (COVID-19) represents a global issue. The bidimensional material graphene has captured much attention due to promising antimicrobial applications and has also demonstrated antiviral efficac...
Active matter therapeutics [0.03%]
主动物质疗法
Arijit Ghosh,Weinan Xu,Neha Gupta et al.
Arijit Ghosh et al.
Nanotherapies based on micelles, liposomes, polymersomes, nanocapsules, magnetic nanoparticles, and noble metal nanoparticles have been at the forefront of drug delivery in the past few decades. Some of these nanopharmaceuticals have been c...
Krystina L Hess,Igor L Medintz,Christopher M Jewell
Krystina L Hess
Vaccines and immunotherapies have changed the face of health care. Biomaterials offer the ability to improve upon these medical technologies through increased control of the types and concentrations of immune signals delivered. Further, the...
Clinical Cancer Nanomedicine [0.03%]
临床癌症纳米医学
Joy Wolfram,Mauro Ferrari
Joy Wolfram
Nanotechnology offers new solutions for the development of cancer therapeutics that display improved efficacy and safety. Although several nanotherapeutics have received clinical approval, the most promising nanotechnology applications for ...
Ultrasmall Noble Metal Nanoparticles: Breakthroughs and Biomedical Implications [0.03%]
超小型贵金属纳米颗粒：突破与生物医学意义
Xingya Jiang,Bujie Du,Yingyu Huang et al.
Xingya Jiang et al.
As a bridge between individual atoms and large plasmonic nanoparticles, ultrasmall (core size
Nanoparticle translocation and multi-organ toxicity: A particularly small problem [0.03%]
纳米颗粒迁移和多器官毒性：一个小而不容忽视的问题
Jennifer B Raftis,Mark R Miller
Jennifer B Raftis
Environmental nanoparticles and manufactured nanoparticles (MNMs) can share many of the same physicochemical properties and, therefore, could have similar toxicological profiles. Inhalation of nanoparticles in air pollution has effects thro...