Zhongmin Tang,Xingcai Zhang,Yiqing Shu et al.
Zhongmin Tang et al.
In just a few months, SARS-CoV-2 and the disease it causes, COVID-19, created a worldwide pandemic. Virologists, biologists, pharmacists, materials scientists, and clinicians are collaborating to develop efficient treatment strategies. Over...
I R S Ribeiro,R F da Silva,C P Silveira et al.
I R S Ribeiro et al.
The lack of targeting efficacy has frequently led functionalized nanoparticles to accumulate in unwanted cells and tissues while boosting toxicity-related effects. Conversely, viruses are natural nanoparticles that precisely and responsivel...
Biomimetic fibrin-targeted and H2O2-responsive nanocarriers for thrombus therapy [0.03%]
用于血栓治疗的仿生纤维蛋白靶向和H2O2响应纳米载体
Yi Zhao,Ruosen Xie,Nisakorn Yodsanit et al.
Yi Zhao et al.
Thrombosis is a principle cause of various life-threatening cardiovascular diseases. However, current antithrombotic treatments using drugs only offer limited efficacy due to short half-life, low targeting ability to the thrombus site, and ...
Exploring the role of triazole functionalized heteroatom co-doped carbon quantum dots against human coronaviruses [0.03%]
三唑功能化杂原子共掺杂碳量子点对人冠状病毒的作用探究
Piyush Garg,Sujata Sangam,Dakshi Kochhar et al.
Piyush Garg et al.
Preventing the trajectory of human coronaviruses including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic could rely on the sprint to design a rational roadmap using breakneck strategies to counter its prime chall...
Yongjiu Chen,Juan Ma,Ming Xu et al.
Yongjiu Chen et al.
The recent COVID-19 outbreak has increasingly engaged researchers in the search for effective antiviral drugs as well as therapeutic treatment options. The shortcomings of existing antiviral agents such as narrow spectrum and low bioavailab...
Prince Allawadhi,Amit Khurana,Sachin Allwadhi et al.
Prince Allawadhi et al.
The COVID-19 pandemic has emerged as an unprecedented global healthcare emergency and has devastated the global economy. The SARS-CoV-2 virus replicates in the host cells and is seemingly much more virulent compared to other flu viruses, as...
Multivalent nanomedicines to treat COVID-19: A slow train coming [0.03%]
用于治疗COVID-19的多价纳米药物：姗姗来迟的火车
Tanveer A Tabish,Michael R Hamblin
Tanveer A Tabish
The high transmission rate and serious consequences of the unprecedented COVID-19 pandemic make it challenging and urgent to identify viral pathogens and understand their intrinsic resistance mechanisms, to pave the way for new approaches t...
Marcel Alexander Heinrich,Byron Martina,Jai Prakash
Marcel Alexander Heinrich
With the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002, the middle east respiratory syndrome CoV (MERS-CoV) in 2012 and the recently discovered SARS-CoV-2 in December 2019, the 21st first century has so far faced the outb...
Covid-19 acute responses and possible long term consequences: What nanotoxicology can teach us [0.03%]
新冠急性反应和可能的长期后果：纳米毒理学能告诉我们什么
Pia A S Kinaret,Giusy Del Giudice,Dario Greco
Pia A S Kinaret
Long-term effects of Covid-19 disease are still poorly understood. However, similarities between the responses to SARS-CoV-2 and certain nanomaterials suggest fibrotic pulmonary disease as a concern for public health in the next future. Cro...
Tianjiao Ji,Daniel S Kohane
Tianjiao Ji
Many diseases and conditions affect a relatively localized area of the body. They can be treated either by direct deposition of drug in the target area, or by giving the drug systemically. Here we review nanoparticle-based approaches to ach...