Jinping Wang,Beilu Zhang,Jingyu Sun et al.
Jinping Wang et al.
Porous nanomaterials with high surface area, tunable porosity, and large mesopores have recently received particular attention in cancer therapy and imaging. Introduction of additional pores to nanostructures not only endows the tunability ...
Inherited and acquired corona of coronavirus in the host: Inspiration from the biomolecular corona of nanoparticles [0.03%]
冠状病毒宿主面的继承与获得的冠层：源自纳米颗粒生物分子冠层的启发
Jie Gao,Li Zeng,Linlin Yao et al.
Jie Gao et al.
The family of coronavirus are named for their crown shape. Encoded by the genetic material inherited from the coronavirus itself, this intrinsic well-known "viral corona" is considered an "inherited corona". After contact with mucosa or the...
Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm [0.03%]
选择性肺靶向的25-羟基胆固醇纳米药物用于抑制新冠肺炎相关细胞因子风暴
Hyelim Kim,Han Sol Lee,June Hong Ahn et al.
Hyelim Kim et al.
In response to the coronavirus disease-19 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), global efforts are focused on the development of new therapeutic interventions. For the treatment of COVID...
Amit Khurana,Prince Allawadhi,Isha Khurana et al.
Amit Khurana et al.
The emergency use authorization (EUA) by the US-FDA for two mRNA-based vaccines BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) has brought hope of addressing the COVID-19 pandemic which has killed more than two million people globally. ...
Towards Microfluidic-Based Exosome Isolation and Detection for Tumor Therapy [0.03%]
基于微流控的外泌体捕获与检测技术在肿瘤治疗中的应用展望
Jie Wang,Peng Ma,Daniel H Kim et al.
Jie Wang et al.
Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer membrane structure of 30-150 nm in diameter. Their discovery and application have brought breakthroughs in numerous areas, such as liquid biopsies, canc...
Engineering a self-navigated MnARK nanovaccine for inducing potent protective immunity against novel coronavirus [0.03%]
一种工程化的自我导航MnARK纳米疫苗诱导针对新型冠状病毒的强力保护性免疫能力
Yaling Wang,Yuping Xie,Jia Luo et al.
Yaling Wang et al.
Effective vaccines are vital to fight against the COVID-19 global pandemic. As a critical component of a subunit vaccine, the adjuvant is responsible for strengthening the antigen-induced immune responses. Here, we present a new nanovaccine...
2D MXenes with antiviral and immunomodulatory properties: A pilot study against SARS-CoV-2 [0.03%]
具有抗病毒和免疫调节性能的二维MXene材料：针对SARS-CoV-2的初步研究
Mehmet Altay Unal,Fatma Bayrakdar,Laura Fusco et al.
Mehmet Altay Unal et al.
Two-dimensional transition metal carbides/carbonitrides known as MXenes are rapidly growing as multimodal nanoplatforms in biomedicine. Here, taking SARS-CoV-2 as a model, we explored the antiviral properties and immune-profile of a large p...
Chao Wang,Mei Liu,Zhifei Wang et al.
Chao Wang et al.
The current widespread of COVID-19 all over the world, which is caused by SARS-CoV-2 virus, has again emphasized the importance of development of point-of-care (POC) diagnostics for timely prevention and control of the pandemic. Compared wi...
What NIR photodynamic activation offers molecular targeted nanomedicines: Perspectives into the conundrum of tumor specificity and selectivity [0.03%]
近红外光动力激活赋予分子靶向纳米药物的能力及其对肿瘤特异性和选择性难题的新视角
Chanda Bhandari,Mina Guirguis,N Anna Savan et al.
Chanda Bhandari et al.
Near infrared (NIR) photodynamic activation is playing increasingly critical roles in cutting-edge anti-cancer nanomedicines, which include spatiotemporal control over induction of therapy, photodynamic priming, and phototriggered immunothe...
Valentina Palmieri,Flavio De Maio,Marco De Spirito et al.
Valentina Palmieri et al.
Coronavirus Disease 2019 (COVID-19) is one of the biggest challenges of the 21st century. While researchers are working on vaccine development and elucidating the mechanism of action and evolution of the harmful SARS-CoV-2, the current most...