Micro/nanoengineered technologies for human pluripotent stem cells maintenance and differentiation [0.03%]
用于人类多能干细胞的维持和分化的微/纳米工程技术创新技术
Sajedeh Nasr Esfahani,Agnes M Resto Irizarry,Xufeng Xue et al.
Sajedeh Nasr Esfahani et al.
Human pluripotent stem cells (hPSCs) are a promising source of cells for cell replacement-based therapies as well as modeling human development and diseases in vitro. However, achieving fate control of hPSC with a high yield and specificity...
The success of nanomedicine [0.03%]
纳米医学的成功
Twan Lammers,Mauro Ferrari
Twan Lammers
In recent years, the promise and prospects of nanomedicine have been controversially discussed. We here argue that nanomedicine has undeniably been successful, not only academically and preclinically, but also industrially and clinically. T...
Self-resetting molecular probes for nucleic acids detection enabled by fuel dissipative systems [0.03%]
由燃料耗散体系实现的用于核酸检测的自复位分子探针
Na Li,Yuee Zhao,Yu Liu et al.
Na Li et al.
A once-in-a-century global public health crisis, the COVID-19 pandemic has damaged human health and world economy greatly. To help combat the virus, we report a self-resetting molecular probe capable of repeatedly detecting SARS-CoV-2 RNA, ...
Endocytosis of abiotic nanomaterials and nanobiovectors: Inhibition of membrane trafficking [0.03%]
非生物纳米材料和纳米载体的胞吞作用：抑制膜转运
Pooyan Makvandi,Meiling Chen,Rossella Sartorius et al.
Pooyan Makvandi et al.
Humans are exposed to nanoscopical nanobiovectors (e.g. coronavirus SARS-CoV-2) as well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or intentionally. Understanding the interactions of cell membranes with the...
Systemic antiviral immunization by virus-mimicking nanoparticles-decorated erythrocytes [0.03%]
病毒模拟纳米颗粒修饰的红细胞全身抗病毒免疫注射
Lu Wang,Xinyue Wang,Fengmin Yang et al.
Lu Wang et al.
New vaccine technologies are urgently needed to produce safe and effective vaccines in a more timely manner to prevent future infectious disease pandemics. Here, we describe erythrocyte-mediated systemic antiviral immunization, a versatile ...
Antiviral nanoparticles for sanitizing surfaces: A roadmap to self-sterilizing against COVID-19 [0.03%]
用于表面消毒的抗病毒纳米颗粒：对抗COVID-19的自消毒路线图
Neil Lin,Daksh Verma,Nikhil Saini et al.
Neil Lin et al.
Nanoparticles provide new opportunities in merging therapeutics and new materials, with current research efforts just beginning to scratch the surface of their diverse benefits and potential applications. One such application, the use of in...
Antibody cooperative adsorption onto AuNPs and its exploitation to force natural killer cells to kill HIV-infected T cells [0.03%]
抗体在金纳米颗粒上的协同吸附及用于迫使自然杀伤细胞杀死人类免疫缺陷病毒感染的T细胞
Antonio Astorga-Gamaza,Michele Vitali,Mireya L Borrajo et al.
Antonio Astorga-Gamaza et al.
HIV represents a persistent infection which negatively alters the immune system. New tools to reinvigorate different immune cell populations to impact HIV are needed. Herein, a novel nanotool for the specific enhancement of the natural kill...
Platelet membrane and stem cell exosome hybrid enhances cellular uptake and targeting to heart injury [0.03%]
platelet膜和干细胞外泌体混合增强细胞摄取和针对心脏损伤作用
Shiqi Hu,Xianyun Wang,Zhenhua Li et al.
Shiqi Hu et al.
Exosomes from mesenchymal stem cells have been largely studied as therapeutics to treat myocardial infarctions. However, exosomes injected for therapeutic purposes face a number of challenges, including competition from exosomes already in ...
Self-assembled peptide and protein nanostructures for anti-cancer therapy: Targeted delivery, stimuli-responsive devices and immunotherapy [0.03%]
用于抗癌治疗的自组装肽和蛋白质纳米结构：靶向递送、刺激响应装置和免疫疗法
Masoud Delfi,Rossella Sartorius,Milad Ashrafizadeh et al.
Masoud Delfi et al.
Self-assembled peptides and proteins possess tremendous potential as targeted drug delivery systems and key applications of these well-defined nanostructures reside in anti-cancer therapy. Peptides and proteins can self-assemble into nanost...
TiO2 supported single Ag atoms nanozyme for elimination of SARS-CoV2 [0.03%]
负载单个Ag原子的TiO₂纳米酶用于消除SARS-CoV-2病毒
Daji Wang,Bin Zhang,Hui Ding et al.
Daji Wang et al.
The outbreak of SARS-coronavirus 2 (SARS-CoV2) has become a global health emergency. Although enormous efforts have been made, there is still no effective treatment against the new virus. Herein, a TiO2 supported single-atom nanozyme contai...