Thanaboon Chaemsupaphan,Arteen Arzivian,Rupert W Leong
Thanaboon Chaemsupaphan
Introduction: Ulcerative colitis is a chronic inflammatory condition of the colon driven by aberrant immune activation. Although advanced medical therapies form the cornerstone of ulcerative colitis management, unmet need...
Ellen Boyle,Jessie A Elliott
Ellen Boyle
Introduction: Advances in treatment strategies for gastric and esophageal cancer have led to improved long-term outcomes, however the local and systemic effects of tumor growth, neoadjuvant therapies and surgery, results ...
Naoki Hosoe
Naoki Hosoe
An evidence-based update on the diagnosis and management of irritable bowel syndrome [0.03%]
基于证据的更新：肠易激综合征的诊断和治疗
Christopher J Black,Alexander C Ford
Christopher J Black
Introduction: Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction affecting 5% of the population. The cardinal symptoms are abdominal pain and altered stool form or frequency. ...
Revolutionizing liver fibrosis research: the promise of 3D organoid models in understanding and treating chronic liver disease [0.03%]
革命性肝纤维化研究：三维类器官模型在慢性肝病理解与治疗中的前景
Umashanker Navik,Sumeet Kumar Singh,Amit Khurana et al.
Umashanker Navik et al.
Introduction: Liver fibrosis, marked by excessive extracellular matrix deposition, is a significant consequence of chronic liver injuries from various conditions. It can progress to end-stage liver disease, with liver tra...
Rakhi Maiwall,Fagun Sharma
Rakhi Maiwall
Introduction: Acute kidney injury (AKI) in patients with acute-on-chronic liver failure (ACLF) is driven by the severity of systemic inflammation, acute portal hypertension driving circulatory dysfunction, hyperbilirubine...
F Lusetti,C Bezzio,A De Bernardi et al.
F Lusetti et al.
Introduction: Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), present ongoing challenges despite advances in pathophysiological understanding and therapeutic options. Curr...
The role of noninvasive biomarkers for monitoring cell injury in advanced liver fibrosis [0.03%]
非侵入性生物标志物在肝纤维化细胞损伤监测中的作用
Righetti Riccardo,Felice Cinque,Keyur Patel et al.
Righetti Riccardo et al.
Introduction: Accurate and reliable diagnosis and monitoring of hepatic fibrosis is increasingly important given the variable natural history in chronic liver disease (CLD) and expanding antifibrotic therapeutic options t...
Modulating the microbiome in chronic liver diseases- current evidence on the role of fecal microbiota transplantation [0.03%]
调节慢性肝病中的微生物群-粪便微生物移植作用的当前证据
Srishti Saha,Bernd Schnabl
Srishti Saha
Introduction: The gut microbiota has a complex relationship with the human host and is key to maintaining health. Disruption of the healthy diverse gut microbial milieu plays an important role in the pathogenesis of sever...
Muhammad Umair Tayyub,Deepak Joshi
Muhammad Umair Tayyub