Gastrointestinal manifestations of common variable immunodeficiency: what a gastroenterologist needs to be aware of [0.03%]
常见变量免疫缺陷的胃肠表现：胃肠病学家需要了解的内容
Drew M Levy,Matthew Meriwether,Mary R Schwartz et al.
Drew M Levy et al.
Introduction: Common variable immunodeficiency disorder (CVID) is the most common symptomatic primary immunodeficiency disorder and, given its predilection to affect the gastrointestinal (GI) tract, will be encountered in...
Rome V criteria for pediatric disorders of gut - brain interaction: key updates and clinical implications [0.03%]
儿童胃肠脑相互作用障碍的罗马V诊断标准：关键更新及临床意义
Shaman Rajindrajith,Niranga Devanarayana,Wathsala Hathagoda et al.
Shaman Rajindrajith et al.
Introduction: The Rome criteria have provided the acclaimed global standard for diagnosing pediatric functional gastrointestinal disorders. With the release of Rome criteria V in 2026, the field has undergone a major tran...
Heller myotomy for oesophageal achalasia: risk factors for reintervention - a narrative review [0.03%]
赫勒肌切开术治疗贲门失迟缓症再手术的风险因素-叙事性综述
Arianna Vittori,Renato Salvador,Luca Provenzano et al.
Arianna Vittori et al.
Introduction: Heller myotomy (HM) is an effective and durable treatment for esophageal achalasia. However, some patients experience persistent or recurrent symptoms that require reintervention. Heterogeneous definitions o...
Optimizing nutritional care across the continuum from intensive care to recovery: an expert opinion review [0.03%]
从重症监护到恢复期的营养护理连续性优化：专家意见回顾
Arthur R H van Zanten,Pavel Kohout,Elisabeth De Waele et al.
Arthur R H van Zanten et al.
Introduction: Survivorship after critical illness is frequently complicated by muscle wasting and gastrointestinal (GI) dysfunction, driving prolonged functional impairment. Nutrition is a modifiable determinant across th...
Recent developments in the therapeutic management of acid-related gastrointestinal diseases [0.03%]
酸相关性胃肠疾病治疗的最新进展
Aitor Lanas-Gimeno,Angel Lanas
Aitor Lanas-Gimeno
Introduction: Acid-related gastrointestinal diseases, particularly gastroesophageal reflux disease (GERD) and peptic ulcer disease (PUD), remain major global health burdens despite decades of proton pump inhibitor (PPI)-b...
Immunotherapy plus chemotherapy in advanced biliary tract cancers: pros and cons [0.03%]
免疫疗法联合化疗在晚期胆道癌中的利弊分析
Gagandeep Brar,Juan W Valle
Gagandeep Brar
Introduction: Biliary tract cancers (BTC) are highly immunosuppressive 'cold' tumors with limited treatment options. In unresectable or advanced-stage disease, the combination of immune checkpoint inhibition with chemothe...
Kizuki Yuza,Miho Akabane,Jun Kawashima et al.
Kizuki Yuza et al.
Introduction: Although immune checkpoint inhibitor (ICI)-based combinations have established the frontline standard for advanced hepatocellular carcinoma (HCC), substantial unmet needs persist-limited response rates, prim...
Anti-fibrotic therapy in Crohn's disease: hype or reality-can intestinal fibrosis be targeted effectively? [0.03%]
克罗恩病的抗纤维化治疗：炒作还是现实？肠道纤维化能被有效靶向吗？
Sailish Honap,Axel Dignass,Vipul Jairath et al.
Sailish Honap et al.
Introduction: Fibrostenotic Crohn's disease remains a major unmet clinical need, as currently licensed therapies primarily target inflammation and have not been shown to prevent fibrosis progression or reverse established...
Management of gastric varices: treatment options and opportunities to improve outcomes [0.03%]
胃静脉曲张的治疗选择及改善预后的机遇
Michael B MacIsaac,Alex Wynne,Peter Hayes
Michael B MacIsaac
Introduction: Gastric varices represent a challenging clinical scenario due to the severity of consequences when bleeding occurs, the cohort of patients in which it occurs and a paucity of high-quality prospective data to...