The clinical implications of trial endpoints in immunotherapy for hepatocellular carcinoma [0.03%]
免疫检查点抑制剂治疗肝细胞癌临床试验终点的考量
Xun Zhao,Talia Dufault,Gonzalo Sapisochin et al.
Xun Zhao et al.
Introduction: Investigative work in the treatment of hepatocellular carcinoma is rapidly growing with the advent of immunotherapy. Nonetheless, trial endpoints, and more importantly, clinically meaningful endpoints need t...
Gastrointestinal transit abnormalities in irritable bowel syndrome and their relation to symptoms [0.03%]
肠易激综合征的胃肠转运异常及其与症状的关系
Abdulsalam I Aliyu,Ryo Katsumata,Hans Törnblom et al.
Abdulsalam I Aliyu et al.
Introduction: Measurement of gastrointestinal (GI) transit is increasingly becoming a valuable tool in understanding the pathophysiology of symptoms of many digestive diseases including irritable bowel syndrome (IBS). The...
Kenneth S H Chok,Tiffany Y T Joeng,Darren M C Poon
Kenneth S H Chok
Introduction: Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer. Photon radiotherapy shows efficacy in treating HCC but carries risks of high exit dose and radiation-induced liver disease. Add...
Living donor liver transplant for Alcohol-Associated Hepatitis: considerations and global perspectives [0.03%]
酒精性肝炎活体供肝移植的考量及全球视角
Brian Horwich,Norah Terrault,Hyosun Han
Brian Horwich
Introduction: In carefully selected individuals, outcomes of early deceased donor liver transplantation (
Recent developments in managing luminal microbial ecology in patients with inflammatory bowel disease: from evidence to microbiome-based diagnostic and personalized therapy [0.03%]
炎症性肠病患者管腔微生物生态管理的最新进展：从证据到微生态诊断和个性化治疗
Erica Bonazzi,Caterina De Barba,Greta Lorenzon et al.
Erica Bonazzi et al.
Introduction: Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a chronic condition characterized by abnormal immune responses and intestinal inflammation. Emerging evidence highlights...
Matthew K Smith,Aldo J Montano-Loza
Matthew K Smith
Introduction: Autoimmune hepatitis (AIH) is a relatively infrequent and complex liver disease characterized by acute or chronic inflammation, interface hepatitis in histology examination, elevation of immunoglobulin G (Ig...
Palliative care & management of symptoms in advanced liver disease: an expert review [0.03%]
晚期肝病的姑息治疗及症状管理：专家综述
Jessica L Allen,Richard K Sterling
Jessica L Allen
Introduction: Chronic liver disease (CLD) is a leading cause of death worldwide. End-stage liver disease (ESLD) causes a rapid and progressive decline in health and quality of life (QOL) and creates significant suffering ...
Specialized and standard nutritional formulas for the dietary management of pediatric patients with Crohn's disease: a systematic literature review [0.03%]
儿童克罗恩病饮食管理的专科和常规营养配方：系统文献回顾
Richard K Russell,Andrew Fagbemi,Jalil Benyacoub et al.
Richard K Russell et al.
Introduction: This systematic literature review (SLR) aims to compare the clinical, humanistic, and economic outcomes associated with specialized and standard nutritional formulas for the treatment of mild-to-moderate ped...
Medical management of acute severe ulcerative colitis in the hospitalized patient [0.03%]
住院患者急性重度溃疡性结肠炎的内科治疗
Loren G Rabinowitz,Ajay Gade,Joseph D Feuerstein
Loren G Rabinowitz
Introduction: Approximately one in every four patients with ulcerative colitis will develop acute severe ulcerative colitis (ASUC). Historically, this was management with intravenous steroids and surgery when steroids fai...
Transition of care in pediatric hereditary polyposis: the why, how and to whom [0.03%]
儿童遗传性息肉病的护理过渡：为什么、如何以及过渡给谁
Thomas M Attard,Ajay Bansal,Caitlin E Lawson et al.
Thomas M Attard et al.
Introduction: Transition of care (TOC) is a process that must be planned and executed in a coordinated manner factoring patient, family, disease, and healthcare system. Among youth with gastrointestinal hereditary polypos...