Exosome-transmitted miR-30a-5p enhances cell proliferation, migration, and invasion in ovarian cancer [0.03%]
细胞外囊泡递送的miR-30a-5p促进卵巢癌细胞增殖、迁移和侵袭
Jian Cao,Huan Wang,Jing Yang et al.
Jian Cao et al.
Background: Ovarian cancer (OC) causes the highest rates of mortality among women's genital tract malignancies. Micro-ribonucleic acid (miRNA), the most abundant long noncoding RNAs transmitted by exosomes, has been revea...
Angelica acutiloba Kitagawa flower induces A549 cell pyroptosis via the NF-κB/NLRP3 pathway for anti-lung cancer effects [0.03%]
柴胡花通过NF-κB/NLRP3途径诱导A549细胞pyroptosis的抗肺癌作用
Yonghu Chen,Fangying Zhu,Xianhua Che et al.
Yonghu Chen et al.
Angelica acutiloba Kitagawa, a traditional medicinal herb of the Umbelliferae family, has been demonstrated to have anticancer activity. In this study, we investigated the anti-lung cancer effects of two compounds extracted from A. acutilob...
Polyploid cell dynamics and death before and after PEG-treatment of a NIH/3T3 derived culture: vinblastine effects on the regulation of cell subpopulations heterogeneity [0.03%]
秋水仙素对NIH/3T3细胞系派生培养体系中PEG诱导的多倍体细胞动态学和死亡的影响：对异源细胞亚群数量调节的作用
Alessandra Spano,Luigi Sciola
Alessandra Spano
Background: Neoplastic subpopulations can include polyploid cells that can be involved in tumor evolution and recurrence. Their origin can be traced back to the tumor microenvironment or chemotherapeutic treatment, which ...
Preeclampsia-associated lncRNA FEZF1-AS1 regulates cell proliferation and apoptosis in placental trophoblast cells through the ELAVL1/NOC2L axis [0.03%]
子痫前期相关长链非编码RNA FEZF1-AS1通过ELAVL1/NOC2L轴调节胎盘滋养细胞的增殖和凋亡
Xudong Zhao,Fengyun Su,Qing Guo et al.
Xudong Zhao et al.
Background: LncRNAs have been shown to be involved in and control the biological processes of multiple diseases, including preeclampsia (PE). The impairment of trophoblast cell proliferation is recognized as a significant...
Slik maintains tissue homeostasis by preventing JNK-mediated apoptosis [0.03%]
Slik通过抑制JNK介导的细胞凋亡来维持组织稳态
Chenglin Li,Xiaojie Zhu,Xinyue Sun et al.
Chenglin Li et al.
Background: The c-Jun N-terminal kinase (JNK) pathway is an evolutionarily conserved regulator of cell death, which is essential for coordinating tissue homeostasis. In this study, we have characterized the Drosophila Ste...
Kynureninase knockdown inhibits cisplatin resistance in vivo and in vitro and impacts the prognosis of cervical adenocarcinoma [0.03%]
下调犬尿氨酸酶抑制顺铂耐药的体内和体外研究及其影响宫颈腺癌预后的价值
Jun-Wen Zhang,Ya-Nan Wang,Mei-Ling Zhong et al.
Jun-Wen Zhang et al.
Background: Chemotherapy resistance is a leading cause of treatment failure in cases of cervical adenocarcinoma (ADC), and no effective treatment approach has yet been found. We previously identified the differentially ex...
Rapid and accurate genotyping of human SNP rs671 in aldehyde dehydrogenase 2 gene using one-step CRISPR/Cas12b assay without DNA amplification [0.03%]
无需DNA扩增一步式CRISPR/Cas12b基因分型技术快速准确检测人ALDH2基因rs671多态性
Fang Wu,Yong Xue,Yan Wang et al.
Fang Wu et al.
Background: The SNP rs671 of Human aldehyde dehydrogenase (ALDH) is G-A transition at 1510th nucleotides, which is an important clinical indicator of alcoholic liver disease, digestive tract cancer and some drug efficienc...
The roles of METTL3 on autophagy and proliferation of vascular smooth muscle cells are mediated by mTOR rather than by CDK1 [0.03%]
METTL3通过mTOR而不是CDK1介导血管平滑肌细胞自噬和增殖的作用
Hanshen Luo,Xingliang Wu,Bo Huo et al.
Hanshen Luo et al.
Background: Aberrant proliferation of vascular smooth muscle cells (VSMCs) is the cause of neointima formation followed by vascular injury. Autophagy is involved in this pathological process, but its function is controver...
Expression of genes regulating cell division in porcine follicular granulosa cells [0.03%]
调控猪卵泡颗粒细胞增殖相关基因的表达
Jakub Kulus,Wiesława Kranc,Magdalena Kulus et al.
Jakub Kulus et al.
Background: Cell cycle regulation influences the proliferation of granulosa cells and affects many processes related to ovarian folliclular growth and ovulation. Abnormal regulation of the cell cycle can lead to many dise...
Role of microRNAs in regulation of doxorubicin and paclitaxel responses in lung tumor cells [0.03%]
微小核糖核酸在调节肺肿瘤细胞中多柔比星和紫杉醇反应中的作用
Amirhosein Maharati,Meysam Moghbeli
Amirhosein Maharati
Lung cancer as the leading cause of cancer related mortality is always one of the main global health challenges. Despite the recent progresses in therapeutic methods, the mortality rate is still significantly high among lung cancer patients...