METTL3-mediated m6A methylation of LncRNA DUXAP8 promoted esophageal squamous cell carcinoma progression by activating the PI3K/AKT signaling pathway [0.03%]
METTL3介导的DUXAP8m6A甲基化通过激活PI3K / AKT信号通路促进食管鳞癌进展
Peiyuan Wang,Suyu Chen,Mengxia Lei et al.
Peiyuan Wang et al.
Integrating genetic crosstalk between atherosclerosis and lung adenocarcinoma to advance precision diagnosis and treatment [0.03%]
整合遗传学上的相互作用以期在动脉粥样硬化和肺腺癌的精确诊断和治疗上有所推进
Haojie Dai,Xuchen Wang,Qiwen Wu et al.
Haojie Dai et al.
There is evidence that atherosclerosis is a "tumor-like" disease and has similar genetic mutations to lung adenocarcinoma. In addition, the treatment and progression of lung adenocarcinoma can contribute to the development of atherosclerosi...
Iman Akhlaghipour,Negin Taghehchian,Meysam Moghbeli
Iman Akhlaghipour
Cancer, as one of the main causes of human deaths, has an adverse effect on the quality of life in cancer patients. Despite many advances in diagnostic and therapeutic methods, there is still a poor prognosis in cancer patients that can be ...
DNMT3B blocks TAL1-mediated PKM2 transcriptional repression to promote non-small cell lung cancer progression through inducing glycolysis [0.03%]
DNA甲基化转移酶DNMT3B通过促进PKM2诱导的糖酵解阻止TAL1介导的PKM2转录抑制以促进非小细胞肺癌进展
Yucheng Guo,Bin Xu,Weimin Mao et al.
Yucheng Guo et al.
Background: Non-small cell lung cancer (NSCLC) is a major subtype of lung cancer, with high mortality and limited treatment approaches. This paper explores the function of TAL1 in NSCLC progression and glycolysis and its ...
Long noncoding RNA TMPO-AS1 upregulates chromosomal passenger complex expression to promote cell proliferation in lung cancer via sponging microRNA let-7b-5p [0.03%]
长链非编码RNA TMPO-AS1通过吸附microRNA let-7b-5p上调染色体乘客复合物的表达以促进肺癌细胞增殖
Prerna Vats,Bhavika Baweja,Chainsee Saini et al.
Prerna Vats et al.
Objective: This study aims to develop a ceRNA network associated with the chromosomal passenger complex (CPC) and identify a prognostic signature in lung cancer, the most diagnosed globally, to better understand the molec...
LncPRESS1 promotes the progression and cisplatin resistance of breast cancer through upregulation of ENO1 and activation of glycolysis [0.03%]
长链非编码RNA LncPRESS1通过上调丙酮酸激酶2促进乳腺癌进展和顺铂耐药性
Longzhu Ke,Wei Gao,Yuanxiu Leng et al.
Longzhu Ke et al.
Background: Overexpression or downregulation of long noncoding RNA (lncRNA) plays an essential role in the progression and chemotherapy-resistant of breast cancer (BRCA). LncPRESS1 is a lncRNA regulated by p53, suggesting...
FGF4 drives tumor progression in triple-negative breast cancer via IL6/STAT3-mediated macrophage M2 polarization and immune suppression [0.03%]
FGF4通过IL6/STAT3介导的M2型巨噬细胞极化和免疫抑制促进三阴性乳腺癌进展
Xuanhe Zhang,Shushan Zhang,Yuanyuan Han
Xuanhe Zhang
Objective: This study investigates how Fibroblast Growth Factor 4 (FGF4) drives triple-negative breast cancer (TNBC) progression by modulating macrophage polarization through the IL6/STAT3 signaling axis, with a focus on ...
FGF4 drives tumor progression in triple-negative breast cancer via IL6/STAT3-mediated macrophage M2 polarization and immune suppression [0.03%]
FGF4通过IL6/STAT3介导的巨噬细胞M2极化和免疫抑制驱动三阴性乳腺癌进展
Xuanhe Zhang,Shushan Zhang,Yuanyuan Han
Xuanhe Zhang
Objective: This study investigates how Fibroblast Growth Factor 4 (FGF4) drives triple-negative breast cancer (TNBC) progression by modulating macrophage polarization through the IL6/STAT3 signaling axis, with a focus on ...
Correction: LncRNA NUTM2A-AS1 silencing inhibits glioma via miR-376a-3p/YAP1 axis [0.03%]
纠正：LncRNA NUTM2A-AS1通过miR-376a-3p/YAP1轴沉默抑制胶质瘤
Yuecheng Zeng,Zhenyu Yang,Yang Yang et al.
Yuecheng Zeng et al.
Published Erratum
Cell division. 2025 Aug 22;20(1):21. DOI:10.1186/s13008-025-00157-x 2025
SMAD3 orchestrates RNF167 and STAMBPL1-mediated Sestrin2 ubiquitination to drive gastric cancer progression [0.03%]
SMAD3通过RNF167和STAMBPL1介导的Sestrin2泛素化驱动胃癌进展
Ning Zhang,Na Zhao,Hainan Zhang et al.
Ning Zhang et al.
Background: Gastric cancer (GC) continues to pose a significant global health burden, necessitating a thorough understanding of the molecular mechanisms driving its progression. This study aimed to investigate the regulat...