TFAP2A upregulates FAM83A to suppress ferroptosis and diminish cisplatin sensitivity in non-small cell lung cancer [0.03%]
TFAP2A通过上调FAM83A抑制铁死亡并降低非小细胞肺癌的顺铂敏感性
Qi Sun,Weifeng Qu,Ye Wang et al.
Qi Sun et al.
Background: FAM83A plays a significant role in the development of non-small cell lung cancer (NSCLC). This study elucidated the biological role of FAM83A in ferroptosis and cisplatin (DDP) sensitivity in NSCLC cells. ...
HOXD13 knockdown attenuates apoptosis in prostate cancer via the upregulation of MDM2/p53 signaling [0.03%]
HOXD13敲低通过MDM2/p53信号上调减轻前列腺癌细胞凋亡
Yongliang Ma,Pan Qi,Zongtao Ren et al.
Yongliang Ma et al.
Background: Prostate cancer (PCa) is a common leading cause of death worldwide and is recognized as the second most frequently diagnosed cancer in the male population, making it a significant focus of long-term oncologica...
E3 ubiquitin-protein ligase CBL inhibits non-small cell lung cancer progression via ubiquitination and degradation of KDR [0.03%]
E3泛素蛋白连接酶CBL通过泛素化和降解KDR抑制非小细胞肺癌进展
Zhiyue Tu,Yongshuai Shen,Hua Li
Zhiyue Tu
Background: Non-small cell lung cancer (NSCLC) is the predominant type of lung cancer and continues to be a major cause of cancer-related death globally. The identification of novel molecular targets is essential for deve...
Mitochondrial fission regulator 2 promotes cell proliferation, migration and invasion in hepatocellular carcinoma through regulating PI3K/AKT signaling pathway [0.03%]
线粒体分裂调节因子2通过调控PI3K / AKT信号通路促进肝癌细胞增殖、迁移和侵袭
Qiang Sun,Kaikun Liu,Fangjie Zheng et al.
Qiang Sun et al.
Objective: Mitochondrial fission regulator 2 (MTFR2) is upregulated in multiple cancers, including hepatocellular carcinoma (HCC); however, its mechanistic role in HCC progression remains poorly understood. ...
Artificial intelligence in pancreatic cancer histopathology and diagnostics - implications for clinical decisions and biomarker discovery? [0.03%]
人工智能在胰腺癌病理学和诊断中的应用及其对临床决策和生物标志物发现的影响？
Petra Weselá,Michal Eid,Petr Moravčík et al.
Petra Weselá et al.
Artificial intelligence (AI) and machine learning (ML) are rapidly advancing fields within computer science, driving significant progress in cancer diagnostics. Various ML models have been developed to assist diagnosis, guide therapy decisi...
Correction: PPP2R2A inhibition contributes to preeclampsia by regulating the proliferation, apoptosis, and angiogenesis modulation potential of mesenchymal stem cells [0.03%]
关于PPP2R2A抑制通过调节间充质干细胞的增殖、凋亡及血管生成潜能来促进子痫前期的更正文章
Yan Liu,Fangle Gu,Jun Gao et al.
Yan Liu et al.
Published Erratum
Cell division. 2025 Jun 16;20(1):14. DOI:10.1186/s13008-025-00154-0 2025
UXT enhances melanoma proliferation, migration, and invasion through modulation of the P53 signaling pathway [0.03%]
UXT通过调节P53信号通路促进黑色素瘤的增殖、迁移和侵袭
Kaifen Xiong,Chong Wang,Bingqian Hu et al.
Kaifen Xiong et al.
Melanoma is a highly malignant skin cancer with significant morbidity and mortality, and current treatments have shown limited efficacy in substantially improving clinical outcomes. This highlights an urgent need for alternative therapeutic...
METTL16 accelerates lung adenocarcinoma progression by inducing N6-methyladenosine modification of GTSE1 to regulate p53 pathway and cell cycle [0.03%]
METTL16通过诱导GTSE1的N6-甲基腺苷修饰来调节p53通路和细胞周期从而促进肺腺癌进展
Fang Liu,Sheng Jin
Fang Liu
Background: METTL16 has recently emerged as an N6-methyladenosine (m6A) methyltransferase that serves an integral role in tumor regulation. However, its involvement in lung adenocarcinoma (LUAD) remains unexamined. This i...
Role of HSF1 in cell division, tumorigenesis and therapy: a literature review [0.03%]
HSF1在细胞分裂、肿瘤发生及治疗中的作用：文献综述
Otakar Fiser,Petr Muller
Otakar Fiser
Heat shock factor 1 (HSF1) is the master orchestrator of the heat shock response (HSR), a critical process for maintaining cellular health and protein homeostasis. These effects are achieved through rapid expression of molecular chaperones,...
The m6A modification of LncRNA LINC00200 regulated by WTAP accelerates glioma tumorigenesis by regulating Wnt/β-catenin pathway [0.03%]
WTAP介导的LINC00200m6A修饰通过调节Wnt/β-catenin信号通路促进胶质瘤发生发展
Zhiying Lu,Jing Chen,Chao Luo
Zhiying Lu
Background: Several studies have delineated that dysregulated N6-methyladenosine (m6A) regulators participate in glioma progression. The objective of this study is to investigate the mechanism of Wilms' tumor 1-associatin...