Hana Paculová,Jiří Kohoutek
Hana Paculová
Cyclin-dependent kinases (CDKs) are key regulators of both cell cycle progression and transcription. Since dysregulation of CDKs is a frequently occurring event driving tumorigenesis, CDKs have been tested extensively as targets for cancer ...
Proteins associated with the doubling time of the NCI-60 cancer cell lines [0.03%]
与NCI-60癌细胞系倍增时间相关的蛋白质
Michael Polymenis
Michael Polymenis
The varied nature of human cancers is recapitulated, at least to some extent, in the diverse NCI-60 panel of human cancer cell lines. Here, I used a basic, continuous variable of proliferating cells, their doubling time, to stratify the pro...
Erratum to: Rpl22 is required for IME1 mRNA translation and meiotic induction in S. cerevisiae [0.03%]
Rpl22是酵母S.cerevisiae中IME1 mRNA翻译和有丝分裂诱导所需因子的勘误注释
Stephen K Kim,Randy Strich
Stephen K Kim
[This corrects the article DOI: 10.1186/s13008-016-0024-3.].
Published Erratum
Cell division. 2017 Jul 18:12:5. DOI:10.1186/s13008-017-0031-z 2017
Erratum to: Electrostatic forces drive poleward chromosome motions at kinetochores [0.03%]
图解：静电作用力驱动着赤道板上的染色体向两极运动
L John Gagliardi,Daniel H Shain
L John Gagliardi
[This corrects the article DOI: 10.1186/s13008-016-0026-1.].
Published Erratum
Cell division. 2017 Jul 3:12:4. DOI:10.1186/s13008-017-0030-0 2017
Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control [0.03%]
RB通过多种分子相互作用协同调控细胞周期
Michael J Thwaites,Matthew J Cecchini,Srikanth Talluri et al.
Michael J Thwaites et al.
Background: The G1-S phase transition is critical to maintaining proliferative control and preventing carcinogenesis. The retinoblastoma tumor suppressor is a key regulator of this step in the cell cycle. ...
Maximilian Billmann,Michael Boutros
Maximilian Billmann
Genetic screens have identified many novel components of various biological processes, such as components required for cell cycle and cell division. While forward genetic screens typically generate unstructured 'hit' lists, genetic interact...
The Irr1/Scc3 protein implicated in chromosome segregation in Saccharomyces cerevisiae has a dual nuclear-cytoplasmic localization [0.03%]
参与芽殖酵母染色体分离的Irr1/Scc3蛋白具有核质双重定位特性
Piotr Kowalec,Jan Fronk,Anna Kurlandzka
Piotr Kowalec
Background: Correct chromosome segregation depends on the sister chromatid cohesion complex. The essential, evolutionarily conserved regulatory protein Irr1/Scc3, is responsible for the complex loading onto DNA and for it...
Electrostatic forces drive poleward chromosome motions at kinetochores [0.03%]
静电力量驱动动粒上的向两极移动的染色体运动
L John Gagliardi,Daniel H Shain
L John Gagliardi
Background: Recent experiments regarding Ndc80/Hec1 in force generation at kinetochores for chromosome motions have prompted speculation about possible models for interactions between positively charged molecules at kinet...
Erratum to: The loop-less tmCdc34 E2 mutant defective polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2 [0.03%]
纠错：体外和体内无多泛素化缺陷的环缺失tmCDC34E2突变型酵母株系的生长依赖于Ubp14和Cka2蛋白质
Agnieszka Lass,Ross Cocklin,Kenneth M Scaglione et al.
Agnieszka Lass et al.
[This corrects the article DOI: 10.1186/1747-1028-6-7.].
Published Erratum
Cell division. 2016 Oct 6:11:13. DOI:10.1186/s13008-016-0018-1 2016
The CSL proteins, versatile transcription factors and context dependent corepressors of the notch signaling pathway [0.03%]
CSL蛋白，一种 notch信号通路的多功能转录因子和依赖于上下文环境的核心共抑制子蛋白质
Humberto Contreras-Cornejo,Germán Saucedo-Correa,Javier Oviedo-Boyso et al.
Humberto Contreras-Cornejo et al.
The Notch signaling pathway is a reiteratively used cell to cell communication pathway that triggers pleiotropic effects. The correct regulation of the pathway permits the efficient regulation of genes involved in cell fate decision through...