Thomas A Angelovich,Kathleen Busman-Sahay,Janna Jamal Eddine et al.
Thomas A Angelovich et al.
Purpose of review: Neurocognitive disorders and neuropathology continue to affect a subset of people with HIV (PWH) despite long-term viral suppression with antiretroviral therapy (ART). The mechanisms driving persistent ...
Glucagon-like peptide-1 receptor agonists in the aging population of people with HIV: emerging evidence and clinical implications [0.03%]
人胰高糖素样肽-1受体激动剂在HIV感染人群中应用的证据和临床意义——聚焦老年人群的影响
Lara Haidar,Joseph A C Delaney
Lara Haidar
Purpose of review: The increasing use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) for type 2 diabetes and obesity has generated interest in their potential role among people with HIV (PWH), who experience a hi...
Ekta Singh,Alan L Landay,Matthew L Mendoza
Ekta Singh
Purpose of review: People with HIV (PWH) on effective antiretroviral therapy continue to experience a disproportionate burden of age-related comorbidities and multimorbidity. This review explores HIV-associated aging as a...
Measuring neurocognitive impairment in virally suppressed HIV: HIV-associated neurocognitive disorders, HIV-associated brain injury problems and solutions [0.03%]
艾滋病病毒感染抑制患者的神经认知功能检测：艾滋病相关的神经认知障碍及其脑损伤问题与对策研究
Bruce J Brew,Lucette A Cysique
Bruce J Brew
Purpose of review: To discuss neurocognition measurement in view of current controversies in HIV-associated neurocognitive disorders (HAND). Recent findin...
Rogier W Sanders,Tom G Caniels,John P Moore et al.
Rogier W Sanders et al.
Purpose of review: It is standard practice to protect infants against viruses that they are exposed to early in life, during childhood, or as adults. While HIV-1 is only rarely a risk in the period between the end of brea...
Nanouk Zuidmeer,Jori Symons,Monique Nijhuis
Nanouk Zuidmeer
Purpose of the review: This review summarizes recent advances in understanding HIV infection of the brain, focusing on viral persistence in microglia and associated pathogenesis during viremia and viral suppression. We hi...
Philip J R Goulder,Carlo Giaquinto,Paolo Rossi
Philip J R Goulder
Early intervention, lasting impact: benefits of early antiretroviral therapy and implications for posttreatment control [0.03%]
早期干预，持久获益：高效抗逆转录病毒治疗的早期介入益处及对治疗后控制的意义
Dita C Bolluyt,Godelieve J de Bree,Alexander O Pasternak
Dita C Bolluyt
Purpose of review: Over the past few years, it has become increasingly clear that starting antiretroviral therapy (ART) during acute HIV infection (AHI) leads to a faster viral reservoir decay and partial preservation of ...
Natural killer cells in pediatric HIV cure strategies: from viral control to immunotherapeutics [0.03%]
儿科HIV治愈策略中的自然杀伤细胞：从病毒控制到免疫治疗药物
Nicola Cotugno,Lesley de Armas,Paolo Palma
Nicola Cotugno
Purpose of review: Perinatal HIV infection occurs during a critical window of immune development, in a predominantly naïve immune system, resulting in distinct and unique virologic and immunologic outcomes compared with ...
Nonhuman primate models of HIV reveal reservoir dynamics and promising interventions [0.03%]
非人灵长类动物模型揭示了HIV库特征和有前景的干预措施
Brandon F Keele
Brandon F Keele
Purpose of review: HIV cure research seeks to eradicate the virus from people with HIV (PWH) or provide posttreatment control (PTC) of virus sufficient to block new transmissions and provide better health outcomes. Nonhum...