Clinical significance of quantification of perineural cancer invasion on MRI-targeted prostate biopsy [0.03%]
磁共振靶向前列腺活检量化癌性神经周围浸润的临床意义
Madhurya Ramineni,Ying Wang,Hiroshi Miyamoto
Madhurya Ramineni
Background: MRI-targeted biopsy (T-Bx) has considerably improved the detection of clinically significant prostate cancer, while the clinical impact of perineural invasion (PNI) seen on T-Bx remains unclear. We aimed to de...
High-grade uterine endometrial stromal sarcoma harboring GLI1 and MDM2/CDK4 co-amplifications [0.03%]
伴有GLI1和MDM2/CDK4共扩增的高级别子宫内膜间质肉瘤
Lili Zhang,Lijuan Luan,Lei Zhang et al.
Lili Zhang et al.
GLI1 gene alterations including fusions and amplifications compromise a subset of malignant mesenchymal tumors exhibiting characteristic monomorphic nested morphology and frequent S100 positivity, which mimic glomus tumors or well different...
Integrated in-silico and in-vitro analysis of lncRNA H19/miRNA-675/p53 in OSCC: Structural characterization and molecular docking insights [0.03%]
整合的计算和体外分析OSCC中lncRNA H19/miRNA-675/p53：结构特征与分子对接研究见解
Ramya Sekar,Selvaraj Jayaraman,Vishnupriya Veeraraghavan et al.
Ramya Sekar et al.
Background: Long non-coding RNAs (lncRNA) H19 has drawn special attention because of its varied role in several malignancies, including OSCC. Therefore, this study was conducted to assess the association between H19-miR67...
Diagnostic value of AHNAK2 immunohistochemical expression in papillary thyroid carcinoma: an immunohistochemical study [0.03%]
AHNAK2免疫组化表达在乳头状甲状腺癌中的诊断价值：一项免疫组化研究
Xinyi Zhang,Lingli Chen,Minying Deng et al.
Xinyi Zhang et al.
Multiple immunohistochemical markers including galectin-3 and BRAF V600E have been used to identify benign and malignant thyroid tumors. AHNAK nucleoprotein 2 (AHNAK2) is a novel oncogene that belongs to the AHNAK protein family and is upre...
Two unusual cases of tongue schwannoma with self-injurious factors: case reports and systemic literature review [0.03%]
两例罕见的舌施万细胞瘤并发自伤因素：病例报告和系统文献回顾
Gefei Du,Jiali Zhang,Xinming Chen et al.
Gefei Du et al.
We present two cases of tongue schwannoma in two young males. The unusual, exogenetic clinical manifestation might be a big challenge for most dentists in making a correct diagnosis. The two patients had no special genetic or environmental ...
Inflammatory fibroid polyps of the colon: a study on the morphological spectrum, immunoexpression characteristics, and outcomes [0.03%]
结肠炎性纤维瘤样息肉的形态学谱系、免疫表型特征及转归研究
Qin Changfei,Zhang Tingzhen,Lin Xiangling et al.
Qin Changfei et al.
Background: Colonic inflammatory fibroid polyps (IFPs) have not been extensively studied. Methods: In this study, we collected nine cas...
Fine-needle aspiration cytology for the diagnosis of ewing's sarcoma in bone: a case report [0.03%]
骨原发性尤文肉瘤细针穿吸细胞学诊断1例报告
Yumeng Cai,Jiangang Gu,Xin Wei et al.
Yumeng Cai et al.
Ewing's sarcoma (ES) is an aggressive small round cell tumor traditionally diagnosed through open biopsy. We present a systematically evaluated case suggesting that standardized ultrasound-guided fine-needle aspiration cytology (FNAC), when...
Haiying Zhan,Neal Fischbach,Melanie Lynch et al.
Haiying Zhan et al.
Background: PTEN hamartoma tumor syndrome (PHTS) is a rare, multisystem disorder caused by germline pathogenic variants in the PTEN gene, predisposing individuals to various malignancies, including breast cancer. ...
Clinical significance and expression of ALDH1 in triple-negative breast cancer [0.03%]
ALDH1在三阴性乳腺癌的表达及临床意义
Yaoyao Yang,Zhuoran Li,Yangyang Zhu et al.
Yaoyao Yang et al.
Background: Triple-negative breast cancer (TNBC) is aggressive and has limited therapeutic options due to the absence of targeted therapies, highlighting the urgent need for prognostic biomarkers linked to cancer stemness...
Metastatic endometrial stromal sarcoma with sex cord and neuroendocrine differentiation harboring a complex gene fusion [0.03%]
具有性索和神经内分泌分化的复杂基因融合的子宫内膜间质肉瘤转移灶
Rayan Sibira,Katherine Cooke,Aarohi Shah et al.
Rayan Sibira et al.
Background: Low-grade endometrial stromal sarcoma (LGESS) is a malignant stromal tumor characterized by an indolent clinical course, often with late recurrence or distant metastasis after a prolonged period of remission. ...