Deep learning-assisted detection of lymph node metastases in bladder cancer [0.03%]
基于深度学习的膀胱癌淋巴结转移检测辅助方法研究
Adam Gorczynski,Balazs Tarján,Noora Neittaanmäki
Adam Gorczynski
Background: Bladder cancer is the most common malignancy of the urinary tract and is often treated with radical cystectomy with lymph node dissection, followed by a thorough pathological evaluation of the dissected nodes....
Diagnosing carcinoma origin in ultrasound-guided needle biopsies: a context-driven approach anchored in site-specific immunohistochemical markers [0.03%]
基于与位置特异性免疫组化标志物锚定的上下文驱动方法诊断超声引导针活检中的癌起源
Gratiana Hermann,Raluca Ghica,Rares Buiga et al.
Gratiana Hermann et al.
Background: In small-biopsy carcinomas, tumor-origin assignment often relies on limited tissue, clinical-radiologic context, morphology, and immunohistochemistry. Although site-specific markers are widely used to support ...
Correlation of P53 expression and TP53 mutation in stage I lung adenocarcinoma and the predictive value for postoperative recurrence within 5 years [0.03%]
I期肺腺癌p53表达与tp53基因突变的相关性及预测术后五年内复发的价值
Jiting Di,Kang Qi,Gang Lin et al.
Jiting Di et al.
Objective: This study seeks to explore the correlation between P53 expression and TP53 mutations in stage I lung adenocarcinoma, while also assessing their predictive value for postoperative recurrence within 5 years. ...
PRAME immunohistochemistry demonstrates high diagnostic accuracy for distinguishing melanoma from nevi but no observed association with pT stage in cutaneous melanoma: a Vietnamese clinicopathological study [0.03%]
PRAME免疫组化具有高鉴别诊断准确度可区分黑色素瘤与痣但在皮肤黑色素瘤中未见其与pT分期相关：越南临床病理学研究
Giang Huong Tran,Duyen Hoang-My Truong,Lam Ngoc Nguyen et al.
Giang Huong Tran et al.
Background: PRAME immunohistochemistry is a useful adjunct in distinguishing melanoma from benign melanocytic lesions, but its clinicopathologic associations remain incompletely understood, particularly in underrepresente...
Identification of factors associated with intraductal carcinoma of the prostate [0.03%]
与前列腺导管内癌相关的因素的鉴定
Motoki Yamagishi,Casey M Phan,Yoshihiro Nakagami et al.
Motoki Yamagishi et al.
Background: Prostate cancer is a common malignancy. Intraductal carcinoma of the prostate (IDCP) is associated with poor prognosis, but is underreported in certain geographic regions. The presence of IDCP is recently reco...
Tissue-based detection of macrophage-associated YAP1-positive material in human acute liver injury: an exploratory immunopathological biopsy series [0.03%]
人急性肝损伤中基于组织的巨噬细胞相关YAP1阳性物质检测：一项探索性免疫病理活检系列研究
Hiroteru Kamimura,Kenya Kamimura,Shuji Terai
Hiroteru Kamimura
Background: Yes-associated protein 1 (YAP1), a downstream effector of the Hippo pathway, is implicated in hepatocellular stress, ductular reaction, and tissue repair. Experimental studies suggest that injured YAP1-activat...
Integrating ANP32A expression with Ann Arbor stage refines prognostic stratification in extranodal NK/T-cell lymphoma [0.03%]
ANP32A表达与Ann Arbor分期联合分层可改善结外鼻型NK/T细胞淋巴瘤预后判断
Yajun Huo,Zhiqi Zhang,Enjie Liu et al.
Yajun Huo et al.
Aims: To investigate the expression of acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) in extranodal NK/T-cell lymphoma (ENKTL) and to evaluate its relationship with clinicopathological characterist...
Unlocking thalidomide response as a hemoglobin F augmentation agent in transfusion-dependent β-thalassemia: the genetic impact of BCL11A, HBS1L-MYB, and XmnI polymorphism [0.03%]
用于输血依赖型β-地中海贫血的遗传性HbF增加剂地塞米松的反应：BCL11A，HBS1L-MYB和XmnI多态性的遗传影响
Iram Nazir,Muhammad Younus Jamal Siddiqi,Maeesa Wadood et al.
Iram Nazir et al.
Background: Thalidomide has been found to augment fetal hemoglobin (HbF) synthesis, thereby decreasing transfusion requirements in patients with β-thalassemia. Elevated fetal hemoglobin, influenced by genetic polymorphis...
CLDN18.2 expression identifies a gastric-type phenotype and a potential therapeutic target in pulmonary invasive mucinous adenocarcinoma [0.03%]
CLDN18.2表达确定了肺侵袭性黏液腺癌的胃型表型及潜在治疗靶点
Tingting Bian,Xiaoyu Ren,Daishan Jiang et al.
Tingting Bian et al.
Aims: This study aimed to investigate the clinicopathological and immunophenotypic significance of Claudin18.2 (CLDN18.2) in pulmonary invasive mucinous adenocarcinoma (IMA), with particular focus on its association with ...
Intrapulmonary solitary fibrous tumor: clinicopathological analysis of 29 cases with emphasis on morphological spectrum and immunohistochemical profile [0.03%]
肺孤立性纤维性肿瘤的临床病理分析（强调形态学范围和免疫组化谱系）：29例报告
Xin Zeng,Xiaodong Lin,Lifang Ye et al.
Xin Zeng et al.
Background: Intrapulmonary solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that can mimic pulmonary adenofibroma (PAF) when respiratory epithelium is entrapped. ...