Manousos E Kambouris,Aristea Velegraki,George P Patrinos
Manousos E Kambouris
Technology has offered considerable means to create, enhance, and upkeep biosecurity during the last quarter-century. Mostly this refers to routine health promotion means, more or less modified for the much more complex environment of Biose...
The oral-respiratory interface: modulation of Streptococcus pneumoniae serotype adhesion by the periodontal pathogen Porphyromonas gingivalis W83 [0.03%]
牙科-呼吸道界面：牙龈卟啉单胞菌W83通过调节肺炎链球菌血清型粘附作用影响宿主口腔健康
Chrysanti Murad,Yasmin Hanifa Salma,Imam Megantara et al.
Chrysanti Murad et al.
Background: Porphyromonas gingivalis, a keystone periodontal pathogen synergizes with Streptococcus pneumoniae by upregulating host receptors like the platelet-activating factor receptor (PAFR). This study investigated wh...
Global One Health genomics identify conserved virulence and mobile resistance in the opportunistic pathogen Staphylococcus saprophyticus [0.03%]
全球健康基因组学揭示机会性病原体沙雷氏葡萄球菌中保守的毒力和可移动抗药性
Giarlã Cunha da Silva,Ciro César Rossi
Giarlã Cunha da Silva
Aims: To define the global genomic landscape of Staphylococcus saprophyticus and evaluate the contribution of human, animal, food, and environmental strains to the dissemination of antimicrobial resistance and virulence t...
Plant microfungi Erysiphe palczewskii and Erysiphe convolvuli exhibit allergenic potential in both acute and chronic asthma models in mice [0.03%]
植物微真菌Erysiphe palczewskii和Erysiphe convolvuli在小鼠急性和慢性哮喘模型中表现出致敏潜力
Katarzyna Socała,Piotr Wlaź,Magdalena Krasowska-Kunach et al.
Katarzyna Socała et al.
Background: Allergic reactions have surged to unprecedented levels, impacting about 30% of people globally. Fungi are a significant source of allergens, responsible for approximately 6% of respiratory diseases in the gene...
Probiotic, synbiotic effects on the gut-liver axis: omics-enabled mechanisms and therapeutic windows [0.03%]
益生菌和合生元对肠肝轴的影响：组学促进的作用机制与治疗窗口期
Ghaleb Oriquat,Amr Ali Mohamed Abdelgawwad El-Sehrawy,Waleed K Abdulsahib et al.
Ghaleb Oriquat et al.
The gut-liver axis is a two-way communication network where gut microbes and their metabolites affect liver function, while the liver regulates the intestinal environment through bile acids, immune factors, and antimicrobial substances. Dis...
Combinatorial antimicrobial potential of secondary metabolites and bacteriophages against multi-drug-resistant uropathogenic Escherichia coli [0.03%]
次级代谢产物和噬菌体的抗菌潜力联合对抗多药耐药泌尿致病性大肠杆菌
Shikha Malik,Kiran Nehra,J S Rana
Shikha Malik
Background: Uropathogenic Escherichia coli (UPEC), the leading cause of urinary tract infections, has developed resistance to multiple antibiotics, creating an urgent need for alternative therapeutics. ...
Engineering Lactobacillus for therapeutic delivery and biosensing: lessons from niche adaptation [0.03%]
工程改造乳酸菌用于治疗递送和生物传感：来自生态位适应的启示
Prateeti Pal,Subham Sarkar,Jenifer Rajak et al.
Prateeti Pal et al.
Lactobacillus species are renowned for their probiotic properties and niche adaptability, driven by unique genomic traits, stress-response mechanisms, and biofilm formation. This versatility makes them exceptional candidates for advanced bi...
Antibiofilm activity of cell-free supernatants from bacteria isolated from chronic wounds against Staphylococcus aureus [0.03%]
慢性伤口细菌病原体的游离上清液展示抗生物被膜活性并抑制金黄色葡萄球菌生长
Gabriel Luis Cavalcanti Valente,Diana Legal Ferreira Paiva,Luísa de Souza Assis et al.
Gabriel Luis Cavalcanti Valente et al.
Aims: Staphylococcus aureus is a commensal bacterium and an opportunistic pathogen for humans, as one of the main species in chronic wounds. Seeking alternative strategies against S. aureus in chronic wounds, this study a...
Host transcriptional signatures associated with microbial sequence signals reveal age-related decline in intestinal homeostasis [0.03%]
与微生物序列信号相关的宿主转录特征揭示了肠道稳态随年龄增长而下降
Oluwamayowa S Akinsuyi,Amanda Ojeda,Jessica Xhumari et al.
Oluwamayowa S Akinsuyi et al.
Aims: To characterize age-associated alterations in intestinal barrier homeostasis by integrating host transcriptomic profiles and mucosa-associated microbial sequence signals recovered from human colonic biopsy RNA-seq d...
Synergistic potential between camphene, myrcene, and ceftazidime against medically important bacteria [0.03%]
香芹酚、右旋 Lemon 烯和头孢他啶对临床重要细菌的协同潜力
Davi de Lacerda Coriolano,Jaqueline Barbosa de Souza,Bruno Oliveira de Veras et al.
Davi de Lacerda Coriolano et al.
Aims: Bacterial multidrug resistance represents a major global public health challenge, highlighting the need for alternative or complementary therapeutic strategies. This study evaluated the antibacterial effects of myrc...