Efficacy of chloroquine and hydroxychloroquine for the treatment of hospitalized COVID-19 patients: a meta-analysis [0.03%]
氯喹和羟氯喹对住院COVID-19患者的治疗效果:一项荟萃分析
Jiawen Deng,Fangwen Zhou,Kiyan Heybati et al.
Jiawen Deng et al.
Aims: To evaluate the efficacy and safety of hydroxychloroquine/chloroquine, with or without azithromycin, in treating hospitalized COVID-19 patients. Materials & methods: Data from randomized and observational studies were included in a ra...
Myocarditis and COVID-19 mRNA vaccines: a mechanistic hypothesis involving dsRNA [0.03%]
心肌炎和新冠mRNA疫苗:涉及双链RNA的机制假设
Gerard Milano,Jocelyn Gal,Anne Creisson et al.
Gerard Milano et al.
While tolerance to COVID-19 vaccination is considered satisfactory, a phenomenon of myocarditis, although rare, is becoming a safety concern in mRNA COVID-19 vaccination. The presence of low residual levels of double-strand RNA (dsRNA) has ...
Maryam Shafaati,Massoud Saidijam,Meysam Soleimani et al.
Maryam Shafaati et al.
This article provides a brief overview of DNA vaccines. First, the basic DNA vaccine design strategies are described, then specific issues related to the industrial production of DNA vaccines are discussed, including the production and puri...
Non-SARS, non-MERS human coronavirus infections and risk of Kawasaki disease: a meta-analysis [0.03%]
非典型性肺炎、中东呼吸综合征之外的冠状病毒感染与川崎病发病风险的meta分析
Pratap Kumar Patra,Rashmi Ranjan Das,Aaqib Zaffar Banday et al.
Pratap Kumar Patra et al.
Aim: To study the association between non-SARS, non-MERS human coronavirus (HCoV) infections and Kawasaki disease (KD). Methods: Meta-analysis of observational studies published until 1 May 2021. Results: Out of 571 papers retrieved through...
Pediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 symptoms in Iran [0.03%]
伊朗与SARS-CoV-2症状在时间上相关的儿童多系统炎症综合征
Mehran Akbari,Mojtaba Didehdar,Mohsen Nazari et al.
Mehran Akbari et al.
Aim: We report two cases of pediatric patients diagnosed and treated for pediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS) symptoms. Materials & methods: Two previously healthy 3- and 4-year-old boy...
A plain language summary of how well the single-dose Janssen vaccine works and how safe it is [0.03%]
单剂强生疫苗的效果及其安全性的简明总结
J Sadoff,F Struyf,M Douoguih
J Sadoff
This is a summary of a publication about the ENSEMBLE trial of the Janssen Ad26.COV2.S vaccine against COVID-19, which was published in the New England Journal of Medicine in April 2021. The ENSEMBLE study started in September 2020 and is s...
Temporal variations of country-specific mutational profile of SARS-CoV-2: effect on vaccine efficacy [0.03%]
特定国家SARS-CoV-2突变谱的时序变化:对疫苗效力的影响
Sayantan Laha,Raghunath Chatterjee
Sayantan Laha
Aim: In order to curb the transmission of SARS-CoV-2, nation-wide travel restrictions at different levels were implemented in different countries. Country-specific mutational profile may exist and have an impact on vaccine efficacy. Materia...
Detection and predictors of anti-SARS-CoV-2 antibody levels in COVID-19 patients at 8 months after symptom onset [0.03%]
COVID-19患者出现症状后8个月抗SARS-CoV-2抗体水平的检测及预测因子
Jing Guo,Li Li,Qian Wu et al.
Jing Guo et al.
Aim: To determine SARS-CoV-2 specific IgM and IgG levels of patients with COVID-19 at 8 months after symptom onset and to explore the predictors of antibody levels. Materials & methods: The magnetic chemiluminescence method was used to meas...
SARS-CoV-2 nomenclature: viruses, variants and vaccines need a standardized naming system [0.03%]
SARS-CoV-2的命名法:病毒、变种和疫苗需要一个标准化命名系统
Tariq Khan,Syed Muhammad Jamal
Tariq Khan
The importance of determining the amount of 'therapeutic units' before using convalescent plasma [0.03%]
使用康复血浆前确定“治疗单位”数量的重要性
Yasmine Rangel Vieira,Jorlan Fernandes,Marcelo Alves Pinto et al.
Yasmine Rangel Vieira et al.