Building a better natural killer (NK) cell: Fc receptor engineering strategies for NK cell therapeutics [0.03%]
更好的自然杀伤（NK）细胞的构建：NK细胞治疗的Fc受体工程策略
Kyle W Kroll,Griffin Woolley,R Keith Reeves
Kyle W Kroll
Spillover of Rat Hepatitis E Virus into Humans: An Emerging Zoonosis? [0.03%]
小鼠 hepatitis e 病毒感染人类了吗？
Kush Kumar Yadav,Menuka Bhandari,Xiang-Jin Meng et al.
Kush Kumar Yadav et al.
Rocahepevirus ratti (rat HEV) has become a zoonotic pathogen of growing public health concern. First identified in 2010 in wild rats in Germany, Rocahepevirus ratti-C1 (HEV-C1) was genetically distinct from Paslahepevirus genotypes that cau...
Live long and persist: polyomavirus immune evasion in the brain and kidney [0.03%]
长期潜伏，伺机而动：多瘤病毒的免疫逃逸机制及其在脑和肾脏中的作用
Kalynn M Alexander,Katelyn N Ayers,Aron E Lukacher
Kalynn M Alexander
Polyomaviruses (PyVs) are widespread commensals among vertebrates, including humans, where they silently persist lifelong in healthy hosts. Polyomavirus infection in immunocompromised individuals can cause life-threatening diseases. Of the ...
Gary Dunn,Matthew P Taylor
Gary Dunn
The cells infected by a virus in vivo are critical determinants of infection and disease. These same susceptible cells can also provide a wide range of options for viral propagation. The type of cell used to produce a virus, i.e. the produc...
Amy Lansky,Joseph Prejean,Irene Hall
Amy Lansky
Sara Gianella,Richard Haubrich,Sheldon R Morris
Sara Gianella
Resistance analysis following sotrovimab treatment in participants with COVID-19 during the phase III COMET-ICE study [0.03%]
COMET-ICE三期研究中接受索托韦单抗治疗的COVID-19患者的耐药性分析
Sambhavi Subramanian,Gretja Schnell,Julia di Iulio et al.
Sambhavi Subramanian et al.
Aim: Sotrovimab is an engineered human monoclonal antibody that binds a conserved region of the SARS-CoV-2 spike protein. The COMET-ICE phase III study evaluated sotrovimab for treatment of mild to moderate COVID-19 in nonhospitalized parti...
In silico assessment of diterpenes as potential inhibitors of SARS-COV-2 main protease [0.03%]
茋类天然产物茋双氢氯化物盐作为SARS-CoV-2主要蛋白酶的计算评估
Yousef A Abdelrady,Naeem Mahmood Ashraf,Arslan Hamid et al.
Yousef A Abdelrady et al.
Aim: We aimed to investigate the potential inhibitory effects of diterpenes on SARS-CoV-2 main protease (Mpro). Materials & methods: We...
Expression of TRIM56 gene in SARS-CoV-2 variants and its relationship with progression of COVID-19 [0.03%]
TRIM56基因在SARS-CoV-2变异株中的表达及其与COVID-19进展的关系
Rezvan Tavakoli,Pooneh Rahimi,Mojtaba Hamidi-Fard et al.
Rezvan Tavakoli et al.
Aim: The present study aimed to determine a correlation between differential TRIM56 expression levels and severe infections of COVID-19 between the Alpha, Delta and Omicron BA.5 variants. ...
CpG 684: an effective adjuvant for the inactivated COVID-19 vaccine in mice [0.03%]
CPG 684：一种有效的佐剂，能够增强灭活新冠病毒疫苗在小鼠体内的免疫反应
Jiandong Liu,Tianle Cang,Congli Jiang et al.
Jiandong Liu et al.
Aim: This study used CpG 684 as adjuvant of inactivated COVID-19 vaccine to detect a humoral and cellular immune response in mice. Materials & methods: ...