Similarity between cutaneous reactions due to SARS-CoV-2 and its vaccinations [0.03%]
由SARS-CoV-2及其疫苗引起的皮肤反应的相似性
Ömer Kutlu,Selami Aykut Temiz
Ömer Kutlu
Relevance of cycle threshold values in mass screening by reverse-transcription-PCR during COVID-19 pandemic in Belgium: a decision-making support? [0.03%]
RT-PCR Ct值在比利时新冠疫情期间的大规模筛查中的相关性及其对决策支持作用？
Patrice Dufour,Henry Paridaens,Jean-Marc Senterre et al.
Patrice Dufour et al.
Aim: The Belgium's strategy against COVID-19 was partly based on mass screening. Here, we reported the results observed in a Belgian mass screening center. Materials & methods: Between October 2020 and February 2021, 32,089 samples were col...
Digging for the discovery of SARS-CoV-2 nsp12 inhibitors: a pharmacophore-based and molecular dynamics simulation study [0.03%]
基于药效团和分子动力学模拟的SARS-CoV-2 nsp12抑制剂虚拟筛选研究
Fatemeh Sana Askari,Mohsen Ebrahimi,Jabbar Parhiz et al.
Fatemeh Sana Askari et al.
Aim: COVID-19 is a global health threat. Therapeutics are urgently needed to cure patients severely infected with COVID-19. Objective: to investigate potential candidates of nsp12 inhibitors by searching for druggable cavity pockets within ...
Structural analysis of spike proteins from SARS-CoV-2 variants of concern highlighting their functional alterations [0.03%]
SARS-CoV-2关切变异体刺突蛋白结构分析及其功能改变Highlights
Kundan Solanki,Sajjan Rajpoot,Ashutosh Kumar et al.
Kundan Solanki et al.
Aim: Mutations in the SARS-CoV-2 spike (S) protein have dramatically changed the transmissibility and pathogenicity of the virus. Therefore, we studied the binding affinity of Omicron spike-receptor binding domain (S-RBD) with human ACE2 re...
Cholesterol-lowering drugs for high-risk hypercholesterolemia patients with COVID-19 while on Paxlovid™ therapy [0.03%]
匹司莫米治疗期间的新冠患者的胆固醇降低药物治疗
Alpo Vuorio,Petri T Kovanen,Frederick Raal
Alpo Vuorio
Paxlovid™ is a promising antiviral oral medication for patients at a high risk of a severe form of COVID-19. Regarding COVID-19 patients who have hypercholesterolemia and are at high or very high risk for an acute atherothrombotic cardiova...
Tripartite communication in COVID-19 infection: SARS-CoV-2 pathogenesis, gut microbiota and ACE2 [0.03%]
COVID-19感染中的三方交流：SARS-CoV-2发病机制、肠道微生物群和ACE2
Sara Ahmadi Badi,Shohreh Khatami,Seyed Davar Siadat
Sara Ahmadi Badi
Nothing in SARS-CoV-2 makes sense except in the light of RNA modification? [0.03%]
不了解RNA修饰 就别想搞懂新冠病毒？
Mingmei Zhao,Chunxiao Li,Yu Dong et al.
Mingmei Zhao et al.
The expression pattern of RNA deaminases determines the mutation and evolution of SARS-CoV-2. Keywords: ADAR...
A rare case of septic pulmonary embolism in co-existence with infective endocarditis and COVID-19 [0.03%]
新冠肺炎合并感染性心内膜炎引起的肺部分泌物栓塞罕见病例报告
Yusuf Emre Ozdemir,Adile Sevde Demir,Meryem Sahin Ozdemir et al.
Yusuf Emre Ozdemir et al.
Infective endocarditis (IE) symptoms including fever, fatigue, dyspnea and myalgia are similar in COVID-19 findings. Therefore, the diagnosis of IE may be missed in patients with COVID-19. Co-existence with IE in COVID-19 is rarely reported...
Efficacy and safety of corticosteroid regimens for the treatment of hospitalized COVID-19 patients: a meta-analysis [0.03%]
糖皮质激素治疗住院COVID-19患者的疗效和安全性：一项meta分析研究
Fangwen Zhou,Jiawen Deng,Kiyan Heybati et al.
Fangwen Zhou et al.
Aim: To evaluate the efficacy and safety of corticosteroids for treating hospitalized COVID-19 patients. Materials & methods: Efficacy ...
Andrographolide induces anti-SARS-CoV-2 response through host-directed mechanism: an in silico study [0.03%]
andrographolide通过宿主定向机制诱导抗SARS-CoV-2反应：一项基于计算的研究
Bhabani Shankar Das,Nabarun Chandra Das,Shasank Sekhar Swain et al.
Bhabani Shankar Das et al.
Aim: Considering the present alarming situation of COVID-19 pandemic, we concentrated on evaluating the efficacy of a novel natural antiviral drug-candidate andrographolide against SARS-CoV-2 through an in silico model of study. Materials &...