Influenza A virus-specific CD8 T-cell responses: from induction to function [0.03%]
流感病毒A特异的CD8 T细胞反应：从诱导到功能
Mr Olson,Be Russ,Pc Doherty et al.
Mr Olson et al.
Seasonal influenza virus infection is a leading cause of illness and mortality in young children and the elderly each year. Current influenza vaccines generate protective antibody responses; however, these must be given annually to provide ...
S Vashist,D Bailey,A Putics et al.
S Vashist et al.
The relative contribution of norovirus to disease burden on society has only recently been established and they are now established as a major cause of gastroenteritis in the developed world. However, despite the medical relevance of these ...
Michael Oglesbee,Stefan Niewiesk
Michael Oglesbee
Measles virus is highly neuroinvasive, yet host immune responses are highly effective at limiting neurovirulence in humans. We know that neurons are an important target of infection and that both IFN-γ and -β expression are observed in th...
Future viral vectors for the delivery of asymptomatic herpes epitope-based immunotherapeutic vaccines [0.03%]
用于输送无症状单纯疱疹表位基免疫治疗性疫苗的 future 病毒载体
Aziz Alami Chentoufi,Lbachir BenMohamed
Aziz Alami Chentoufi
Asim V Farooq,Deepak Shukla
Asim V Farooq
The transmission of herpes simplex virus (HSV)-1 by corneal transplantation has rarely been reported. It is believed that these cases have resulted either from reactivated virus traveling from the trigeminal ganglion to the cornea or from l...
Towards a safe, effective vaccine for Rift Valley fever virus [0.03%]
朝安全、有效的 rift valley fever病毒疫苗迈进
Desiree Labeaud
Desiree Labeaud
Rift Valley fever virus (RVFV) is an important animal and human threat and leads to longstanding morbidity and mortality in susceptible hosts. Since no therapies currently exist to treat Rift Valley fever, it remains a public and animal hea...
C David Pauza,David J Riedel,Bruce L Gilliam et al.
C David Pauza et al.
Disruption of circulating γδ T-cell populations is an early and common outcome of HIV infection. T-cell receptor (TCR)-γ2δ2 cells (expressing the Vγ2 and Vδ2 chains of the γδ TCR) are depleted, even though they are minimally suscept...
Newcastle disease virus-like particles as a platform for the development of vaccines for human and agricultural pathogens [0.03%]
新城疫病毒样颗粒作为人类和农业病原体疫苗开发的平台
Trudy G Morrison
Trudy G Morrison
Vaccination is the single most effective way to control viral diseases. However, many currently used vaccines have safety concerns, efficacy issues or production problems. For other viral pathogens, classic approaches to vaccine development...
Immunologic basis for revaccination of HIV-infected children receiving HAART [0.03%]
HIV阳性并接受高效抗逆转录病毒联合治疗儿童的再次免疫接种的免疫学依据
Kaitlin Rainwater-Lovett,William J Moss
Kaitlin Rainwater-Lovett
With increasing access to antiretroviral therapy for children infected with HIV, especially in sub-Saharan Africa, better understanding of the development and maintenance of memory T- and B-cell responses to pathogens after immune reconstit...
Aaron Yun Chen,Jianming Qiu
Aaron Yun Chen
The cytopathic effects induced during parvovirus infection have been widely documented. Parvovirus infection-induced cell death is often directly associated with disease outcomes (e.g., anemia resulting from loss of erythroid progenitors du...