Vanessa Pirrone,David J Libon,Christian Sell et al.
Vanessa Pirrone et al.
Aging is a complicated process characterized by a progressive loss of homeostasis, which results in an increased vulnerability to multiple diseases. HIV-1-infected patients demonstrate a premature aging phenotype and develop certain age-rel...
The effect of alcohol use on IL-6 responses across different racial/ethnic groups [0.03%]
饮酒对不同种族和族裔群体IL-6反应的影响
María José Míguez,Rhonda Rosenberg,Ximena Burbano-Levy et al.
María José Míguez et al.
Aims: Chronic inflammation has become increasingly recognized as a health threat for people living with HIV, given its associations with multiple diseases. Accordingly, the scientific community has prioritized the need to...
Internalization and fusion mechanism of vesicular stomatitis virus and related rhabdoviruses [0.03%]
-vesicularest病毒和其他rhabdovirus的胞吞和融合机制研究
Xiangjie Sun,Shoshannah L Roth,Michele A Bialecki et al.
Xiangjie Sun et al.
Members of the Rhabdoviridae infect a wide variety of animals and plants, and are the causative agents of many important diseases. Rhabdoviruses enter host cells following internalization into endosomes, with the glycoprotein (G protein) me...
Caspase-8 and FLIP regulate RIG-I/MDA5-induced innate immune host responses to picornaviruses [0.03%]
caspase-8和FLIP调节RIG-I/MDA5诱导的皮病毒先天性免疫宿主反应
Iwona A Buskiewicz,Andreas Koenig,Sally A Huber et al.
Iwona A Buskiewicz et al.
Picornaviruses are small, nonenveloped, positive-stranded RNA viruses, which cause a wide range of animal and human diseases, based on their distinct tissue and cell type tropisms. Myocarditis, poliomyelitis, hepatitis and the common cold a...
Experimental vaccines against potentially pandemic and highly pathogenic avian influenza viruses [0.03%]
潜在大流行的高致病性禽流感病毒的实验疫苗
Alaina J Mooney,S Mark Tompkins
Alaina J Mooney
Influenza A viruses continue to emerge and re-emerge, causing outbreaks, epidemics and occasionally pandemics. While the influenza vaccines licensed for public use are generally effective against seasonal influenza, issues arise with produc...
Effect of statin treatments on highly pathogenic avian influenza H5N1, seasonal and H1N1pdm09 virus infections in BALB/c mice [0.03%]
他汀类药物对BALB/c小鼠高致病性禽流感H5N1、季节性和H1N1pdm09病毒感染的影响
Yohichi Kumaki,John D Morrey,Dale L Barnard
Yohichi Kumaki
Statins are used to control elevated cholesterol or hypercholesterolemia, but have previously been reported to have antiviral properties. AIMS: To show efficacy of statins in various influenza virus mouse models. MATERIALS & METHODS: BALB/c...
Tale of a tegument transactivator: the past, present and future of human CMV pp71 [0.03%]
人类巨细胞病毒pp71的过去、现在和未来：一个衣壳转激活因子的故事
Rhiannon R Penkert,Robert F Kalejta
Rhiannon R Penkert
Herpesviruses assemble large virions capable of delivering to a newly infected cell not only the viral genome, but also viral proteins packaged within the tegument layer between the DNA-containing capsid and the lipid envelope. In this revi...
HSV, axonal transport and Alzheimer's disease: in vitro and in vivo evidence for causal relationships [0.03%]
HSV、轴突运输与阿尔茨海默病：体内和体外证据表明病因关系
Elaine L Bearer
Elaine L Bearer
HSV, a neurotropic virus, travels within neuronal processes by fast axonal transport. During neuronal infection HSV travels retrograde from the sensory nerve terminus to the neuronal cell body, where it replicates or enters latency. During ...
Corinna La Rosa,Don J Diamond
Corinna La Rosa
This review will summarize and interpret recent literature regarding the human CMV immune response, which is among the strongest measured and is the focus of attention for numerous research groups. CMV is a highly prevalent, globally occurr...
Guinea Pig Cytomegalovirus (GPCMV): A Model for the Study of the Prevention and Treatment of Maternal-Fetal Transmission [0.03%]
Guinea Pig 巨细胞病毒(GPCMV)：研究母胎垂直传播的防治的模型
Mark R Schleiss,Michael A McVoy
Mark R Schleiss
A major public health challenge today is the problem of congenital cytomegalovirus (CMV) transmission. Maternal-fetal CMV infections are common, occurring in 0.5-2% of pregnancies, and these infections often lead to long-term injury of the ...