Stem cells for osteodegenerative diseases: current studies and future outlook [0.03%]
骨退行性疾病干细胞研究：现状与前景展望
Darcie L McClelland Descalzo,Devon D Ehnes,Nicole I zur Nieden
Darcie L McClelland Descalzo
As the worldwide population grows and life expectancies continue to increase, degenerative diseases of the bones, muscles, and connective tissue are a growing problem for society. Current therapies for osteodegenerative disorders such as ho...
Kim L M Gardien,Esther Middelkoop,Magda M W Ulrich
Kim L M Gardien
Cell therapy as part of the concept of regenerative medicine represents an upcoming platform technology. Although cultured epidermal cells have been used in burn treatment for decades, new developments have renewed the interest in this type...
Gene patents, patenting life and the impact of court rulings on US stem cell patents and research [0.03%]
基因专利、生命专利以及法院判决对美国干细胞专利和研究的影响
Kirstin R W Matthews,Maude L Cuchiara
Kirstin R W Matthews
In June 2013, the US Supreme Court ruled that naturally occurring genes were unpatentable in the case Association for Molecular Pathology v. Myriad Genetics. Up until this decision, Myriad Genetics was the only company in the USA that could...
Mark E Fleming,Husain Bharmal,Ian Valerio
Mark E Fleming
The purpose of this report is to describe regenerative medicine applications in the management of complex injuries sustained by service members injured in support of the wars in Afghanistan and Iraq. Improvements in body armor, resuscitativ...
Challenges in the development of a reference standard and potency assay for the clinical production of RAFT tissue equivalents for the cornea [0.03%]
RAFT角膜组织等效物临床生产参考标准和滴度测定开发中的挑战
Alvena K Kureshi,Rosemary A L Drake,Julie T Daniels
Alvena K Kureshi
Aim: To develop a reference standard and potency assay for Real Architecture For 3D Tissues (RAFT) tissue equivalents intended for use in limbal epithelial stem cell (LESC) therapy for the cornea. ...
Altered hMSC functional characteristics in short-term culture and when placed in low oxygen environments: implications for cell retention at physiologic sites [0.03%]
人骨髓间充质干细胞短期培养和低氧条件下功能特性的改变及其在生理部位细胞滞留中的意义
Owen Bain,Giulia Detela,Hae-Won Kim et al.
Owen Bain et al.
Background: It is very difficult to conserve critical cell characteristics during expansion in culture, particularly those of adult mesenchymal stromal cells (MSCs), whose characteristics can change rapidly even within a ...
Anja C Rasch
Anja C Rasch
Eleftherios Sachlos,Amber Kerstetter-Fogle
Eleftherios Sachlos
Theo Bond
Theo Bond
Stem cell-based therapies for multiple sclerosis: recent advances in animal models and human clinical trials [0.03%]
基于干细胞的多发性硬化症疗法：动物模型和人类临床试验中的最新进展
Sarah E Lutz,Justin Lengfeld,Dritan Agalliu
Sarah E Lutz