Joan M Von Feldt
Joan M Von Feldt
Achim Rothe,Barbara E Power,Peter J Hudson
Achim Rothe
Antibody engineering and protein design have led to the creation of a new era of targeted anti-inflammatory therapies in rheumatology. Recombinant DNA technologies have enabled the selection and humanization of specific antibody fragments i...
Bisphosphonate treatment for patients with chronic nonbacterial osteomyelitis [0.03%]
慢性非细菌性骨髓炎患者的双膦酸盐治疗
Henner Morbach,Martin Stenzel,Hermann J Girschick
Henner Morbach
Andrea Doria,Chiara Briani
Andrea Doria
In this Viewpoint, Drs Doria and Briani highlight recent advances in efforts to improve the long-term prognosis of patients with systemic lupus erythematosus. The strategies discussed aim to prevent both the occurrence of the disease and it...
Is rituximab suitable for use as a first-line biologic therapy for RA? [0.03%]
利妥昔单抗可作为 rheumatoid arthritis的一线生物制剂吗？
Anatole Kleiner,R John Looney
Anatole Kleiner
Cindy Stahn,Frank Buttgereit
Cindy Stahn
The strong anti-inflammatory and immunosuppressive effects of glucocorticoids are mediated primarily by the cytosolic glucocorticoid receptors. These receptors are members of the steroid hormone receptor family, a superfamily of ligand-indu...
Robert M Lowe,Philip J Hashkes
Robert M Lowe
The term 'growing pains' has been used for almost 200 years to refer to the often severe, generally bilateral lower-extremity nocturnal pains experienced by up to one-third of all children at some time during early childhood. No clear mecha...
Is pregabalin a safe and effective treatment for patients with fibromyalgia? [0.03%]
普瑞巴林可有效安全地治疗纤维肌痛综合症吗？
Michael Spaeth
Michael Spaeth