Are statins useful for treating vascular involvement in systemic sclerosis? [0.03%]
他汀类药物治疗系统性硬化症血管受累有效吗？
Jelena Blagojevic,Marco Matucci-Cerinic
Jelena Blagojevic
Research suggests that statins could be useful to treat vascular manifestations related to systemic sclerosis, but data on their potential clinical benefits remain limited. Previous studies suggested that statins increase the number of circ...
Peter E Lipsky
Peter E Lipsky
RADIATE: more treatment options for patients with an inadequate response to tumor necrosis factor antagonists [0.03%]
放射治疗：为对肿瘤坏死因子拮抗剂反应不足的患者提供更多治疗选择
Ernest Choy
Ernest Choy
Over the last decade, the use of tumor necrosis factor (TNF) inhibitors has improved the prognosis of patients with rheumatoid arthritis. Although these agents are more efficacious than traditional DMARDs, a substantial proportion of patien...
Deficiencies in current evaluations of the cost-effectiveness of biologic agents for RA [0.03%]
目前评估生物制剂治疗类风湿性关节炎的成本效益的不足之处
Wilbert B van den Hout
Wilbert B van den Hout
A case of childhood-onset ankylosing spondylitis: diagnosis and treatment [0.03%]
儿童期起病的强直性脊柱炎一例及其诊断和治疗
Rubén Burgos-Vargas
Rubén Burgos-Vargas
Background: A 14-year-old boy with a 6-year history of recurrent arthritis and enthesitis, which had not responded to previous treatment with NSAIDs, sulfasalazine and methotrexate, presented with a severe flare of these ...
There's more to life than everyday function: the challenge of measuring social role participation in ankylosing spondylitis [0.03%]
生活的意义远不止日常功能：银屑病性关节炎患者社会角色参与度测量面临的挑战
Aileen M Davis,Rosalind Wong,Elizabeth M Badley et al.
Aileen M Davis et al.
Symptoms and functional limitations are commonly reported primary outcome measures in ankylosing spondylitis (AS); however, participation has not been widely evaluated, as reflected by the scarcity of literature on the subject. People with ...
The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis [0.03%]
ADAMTS-7和ADAMTS-12在关节炎发病机制中的作用
Chuan-Ju Liu
Chuan-Ju Liu
Loss of articular cartilage caused by extracellular matrix breakdown is the hallmark of arthritis. Degradative fragments of cartilage oligomeric matrix protein (COMP) have been observed in arthritic patients. ADAMTS-7 and ADAMTS-12, two mem...
The molecular basis of pain and its clinical implications in rheumatology [0.03%]
疼痛的分子机制及其在风湿病学中的临床意义
Brendan Bingham,Seena K Ajit,David R Blake et al.
Brendan Bingham et al.
Nociceptive pain in response to peripheral noxious stimuli, and inflammatory pain resulting from tissue damage, serve as warnings that normal bodily function cannot resume until the stimulus abates or the tissue repairs. Stimuli cause numer...
Chad Deal
Chad Deal
Osteoporosis is a worldwide health problem with a high prevalence. Agents for the treatment of osteoporosis are classified as either antiresorptive or anabolic. Antiresorptive agents work by inhibiting the activity of osteoclasts and, there...
Gary S Firestein
Gary S Firestein