Erectile dysfunction in aging men: evidence and insights related to antihypertensive and antidiabetic medications [0.03%]
老年男性勃起功能障碍与降压及降糖药物的证据和见解
Zhan-Peng Liu,Guiting Lin,Xiang-Hu Meng
Zhan-Peng Liu
With global population aging, erectile dysfunction is becoming increasingly prevalent among middle-aged and older men, who frequently present with cardiometabolic comorbidities, such as hypertension and diabetes mellitus. Although these con...
Impact of common heavy metals and trace elements on semen quality: a meta-analysis and bibliometrics [0.03%]
重金属和微量元素对精液质量的影响：meta分析与文献计量学分析
Nai-Yun Li,Lu Zhang,Yong-Han Li et al.
Nai-Yun Li et al.
Emerging evidence highlights a link between heavy metal exposure and semen quality, but discrepancies persist regarding the effects of metals like lead and cadmium across different biological matrices. This systematic review and meta-analys...
A high-glucose diet aggravates experimental autoimmune prostatitis via DHVD3/VDR/ERK axis-mediated Th17 differentiation [0.03%]
高糖饮食通过DHVD3/VDR/ERK轴介导的Th17分化加重实验性自身免疫前列腺炎
Di Niu,Shao-Yu Yue,Xu Wang et al.
Di Niu et al.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent genitourinary disease that has gradually become recognized as a potential autoimmune disease. Our previous research revealed that a high-glucose diet exacerbated expe...
Novel mutations in ZMYND15 expand the phenotypic spectrum to acephalic spermatozoa: abnormal sperm head-tail connection mediated by SUN5 [0.03%]
ZMYND15的新突变扩展了无头部精子表型谱系：通过SUN5介导的异常精子头-尾连接
Qian-Jun Zhang,Hao Lin,Rui-Long Hao et al.
Qian-Jun Zhang et al.
Acephalic spermatozoa syndrome (ASS) is a rare cause of male infertility characterized by sperm tails lacking heads. Although zinc finger MYND-type containing 15 ( ZMYND15 ) mutations are linked to male infertility, their role in ASS is unk...
Genotype-based management of fertilization and cleavage failure: case-series evidence from DNAH10, DNAH12, CFAP47 , and PLCZ1 [0.03%]
基于基因型的受精和卵裂失败管理：DNAH10、DNAH12、CFAP47 和 PLCZ1 的病例系列证据
Ke-Er Gan,Hui-Ling Zhong,Yu Li et al.
Ke-Er Gan et al.
Fertilization and early-cleavage failure are the major causes of assisted reproductive technology failure, but genotype-guided care is underused. We conducted whole-exome sequencing with Sanger confirmation in 20 men from couples with unexp...
Intracavernosal injection of autologous platelet concentrates for managing erectile dysfunction: a meta-analysis of randomized placebo-controlled trials on platelet-rich plasma and platelet-rich fibrin matrix [0.03%]
自体血小板浓缩物阴茎内注射治疗勃起功能障碍：富血小板血浆和富血小板纤维蛋白基质的随机对照试验的meta分析研究
Missy Savira,Ponco Birowo,Nur Rasyid et al.
Missy Savira et al.
Platelet-rich plasma (PRP) and platelet-rich fibrin matrix (PRFM) have gained interest in the last few years as a regenerative therapy for erectile dysfunction (ED). The present study aimed to systematically investigate the efficacy and saf...
The impact of sperm DNA fragmentation index levels on embryo development potential and clinical outcomes in infertile couples undergoing IVF/ICSI treatment [0.03%]
精子DNA损伤指数对行IVF/ICSI治疗夫妇胚胎发育潜能及临床结局的影响
Yu-Chao Zhang,Jing-Yan Wang,Chun-Yan Shen et al.
Yu-Chao Zhang et al.
The sperm DNA fragmentation (SDF) impact on embryo development, particularly regarding the fertilization methods and female age, remains incompletely defined. This study evaluated the effect of the sperm DNA fragmentation index (DFI) on emb...
Dynamic changes of serum albumin-to-globulin ratio predict major adverse cardiovascular events in prostate cancer patients undergoing androgen deprivation therapy [0.03%]
基线血清白蛋白/球蛋白比值及其在雄激素剥夺治疗前列腺癌患者中的动态变化可以预测主要不良心血管事件
Yi-Hong Zhou,Yan Hiu Athena Lee,Yu-Xin Tang et al.
Yi-Hong Zhou et al.
There are rising concerns regarding the cardiovascular diseases associated with androgen deprivation therapy (ADT) for prostate cancer (PCa). This study aims to investigate the relationship between the dynamic changes (from baseline to 3 mo...
Epididymal extracellular vesicles: from intercellular communication to cellular development [0.03%]
epididymis来源的外泌体：从细胞间通讯到细胞发生学作用
Shuang-Ling Zou,Yi Zhang,Xin Yuan et al.
Shuang-Ling Zou et al.
Sperm maturation in the epididymis is a complex and critical process that enables spermatozoa to acquire their motility and fertilizing ability. The epididymis is essential for sperm maturation and storage and provides a unique microenviron...
Multifunctional automated semen analysis system of global SDF and DSBs provides new insights into varicocele diagnosis [0.03%]
全球SDF和DSBs多功能自动化精子分析系统为精索静脉曲张诊断提供新视角
Gian Maria Busetto,Giovanni Barbieri,Piero Fischetti et al.
Gian Maria Busetto et al.
Varicocele is the most common cause of reversible male infertility. Although abnormalities in basic semen parameters are frequently observed, they offer limited value for assessing fertility potential. Elevated sperm DNA fragmentation (SDF)...