Impact and implementation evaluation of Stress First Aid for the Substance Use Outreach Workforce (SFA/SUOW): protocol of a hybrid type I cluster randomized control trial [0.03%]
物质使用外展工作人员压力急救影响和实施评价：集群随机对照试验(I型)方案
Anmol Desai,Katie A McCormick,Juliette Rau et al.
Anmol Desai et al.
Background: Stress First Aid (SFA), an evidence-informed peer support intervention to address occupational stress, has been adapted to the needs of the substance use outreach workforce (SUOW) (SFA/SUOW) and pilot tested w...
Long-term evaluation of a comprehensive bullying prevention program starting in preschool: study protocol for a randomized controlled trial [0.03%]
一项针对学龄前儿童的反欺凌预防项目的长期评估：随机对照试验研究方案
Antoinette Dewandre,Ophélie Courbet,Quentin Daviot et al.
Antoinette Dewandre et al.
Background: Promoting mental health and psychological well-being from early childhood is a growing priority in global education policy. Bullying has emerged as a major threat to children's well-being, and while most schoo...
CHIP-AML22: a complex clinical trial in de novo pediatric AML patients, including a gemtuzumab ozogamicin randomization and targeted therapy with quizartinib in eligible subgroups, within the NOPHO-DB-SHIP consortium [0.03%]
CHIP-AML22：在儿科新诊断的急性髓系白血病患者中的复杂临床试验，包括使用吉妥珠单抗奥唑米星进行随机分组和对符合条件亚组采用的精准治疗quizartinib，纳入NOPHO-DB-SHIP联盟中
Gertjan J L Kaspers,Merlijn van Hamel,Jonas Abrahamsson et al.
Gertjan J L Kaspers et al.
Background: The overall survival of children with newly diagnosed acute myeloid leukemia (AML) in high-income countries has increased to 80% over the past decades. Nevertheless, a significant subset of patients experience...
Integrative Music Therapy for Depression-related Disorders (iMTDep) - study protocol for a randomised controlled trial [0.03%]
综合音乐治疗抑郁症相关障碍（iMTDep）——一项随机对照试验的研究方案
Esa Ala-Ruona,Tiia-Liina Raittila,Marianne Taipale et al.
Esa Ala-Ruona et al.
Background: Depression, anxiety and work-related stress affect a significant number of adults disrupting their productivity, ability to function and attend work. These highly comorbid disorders tend to be difficult to tre...
Effectiveness of abdominal hollowing and piriformis stretching exercises in spondylolisthesis patients: a study protocol for a randomized controlled trial [0.03%]
腰椎滑脱症患者进行腹部空洞化和梨状肌牵拉练习的有效性：一项随机对照试验的研究方案
Ganesh Dey,Mohammad Anwar Hossain,Polok Halder et al.
Ganesh Dey et al.
Background: Lumbar spondylolisthesis is a clinically important cause of chronic low back pain, activity limitation, and reduced functional capacity. Exercise-based physiotherapy is widely recommended for conservative mana...
Effectiveness of adapted physical activity and therapeutic exercise programme in improving chronic fatigue syndrome in long COVID, delivered via hospital-based rehabilitation versus telerehabilitation [0.03%]
针对长期新冠患者慢性疲劳综合征的医院康复与远程康复两种适应性身体活动和治疗性锻炼项目的有效性比较研究
Feroz Kabir,Khin Nyein Yin,Mohammad Saffree Jeffree et al.
Feroz Kabir et al.
Background: Long COVID is a prevalent condition characterised by pain, fatigue, disability, and a multitude of health issues. There are various treatment options for managing long COVID symptoms, including non-pharmacolog...
In-office balloon dilation for baro-challenge-induced Eustachian tube dysfunction: study protocol for a randomized sham-controlled trial [0.03%]
办公室气球扩张术治疗由高海拔引起的咽鼓管功能障碍：随机假手术对照试验研究方案
Mohammad Aleinati,Jennifer L Spiegel,Trung N Le et al.
Mohammad Aleinati et al.
Background: Balloon dilation of the Eustachian tube (BDET) is a potential treatment for Eustachian tube dysfunction (ETD). However, high-quality evidence for its efficacy in baro-challenge-induced ETD (BCETD) is lacking. ...
Effectiveness of peer counselling in addressing psychological distress and exposure to violence among sexual and gender minorities in Nepal: a study protocol for a randomized controlled trial [0.03%]
尼泊尔性少数和性别少数群体同伴咨询效果研究——一项随机对照试验方案
Keshab Deuba,Rachana Shrestha,Reena Koju et al.
Keshab Deuba et al.
Background: The burden of social stressors (discrimination, prejudice, violence, and stigmatization) is disproportionately high among LGBTIQA + (Lesbian, Gay, Bisexual, Transgender, Intersex, Queer and Asexual) individual...
English language ability as an exclusion criterion in emergency research taking place in the East Midlands, its impact on recruitment and a survey of the views of research professionals [0.03%]
东米德兰地区紧急情况下进行的研究以英语能力作为排除标准及其对招募和调查研究专业人士观点的影响
Rachelle Sherman,Andrew Tabner,Graham Johnson
Rachelle Sherman
Background: English language ability is commonly used within eligibility criteria in research, despite limited strategies to assess it objectively. Improving inclusion of underserved groups in research is an important and...
Design of a mobile application and evaluation of its effects on clinical outcomes in patients with dry eye disease: a study protocol for a randomized controlled trial [0.03%]
干眼病移动应用程序的设计及其对临床结局影响的评估：一项随机对照试验的研究方案
Maryam Edalati Khodabandeh,Razieh Farrahi,Mahdi Sargolzaei et al.
Maryam Edalati Khodabandeh et al.
Background: Dry eye is a common ocular surface disorder resulting from tear deficiency or excess tear evaporation. This protocol will be implemented for a study designed to determine the effectiveness of a mobile self-car...