Adrian F Daly,Jean-François Vanbellinghen,Albert Beckers
Adrian F Daly
The familial occurrence of pituitary adenomas has been recognized for many years and currently accounts for approximately 5% of all cases. Molecular, genetic and clinical features of familial pituitary adenomas have been well characterized ...
Polycystic ovary syndrome: a focus on anti-Müllerian hormone levels [0.03%]
多囊卵巢综合征的抗 Mullerian 系统激素水平:focus on anti-Müllerian hormone levels
Teresa Sir-Petermann,Nicolas Crisosto King
Teresa Sir-Petermann
Anti-Müllerian hormone (AMH) is a dimeric glycoprotein exclusively produced by the granulosa cells and reflects the size of the growing follicular pool. Serum AMH levels seem to correlate with the development of preantral and small-antral ...
Paola Sartorato,Anna Patalano,Franco Mantero
Paola Sartorato
Primary aldosteronism (PA) is the most common cause of mineralocorticoid hypertension. Different studies using the plasma aldosterone concentration (PAC)-plasma renin activity ratio (ARR ratio) for the screening of patients with hypertensio...
Giorgio Arnaldi,Marina Cardinaletti,Marco Boscaro
Giorgio Arnaldi
It is well known that transphenoidal surgery is the first line of treatment for Cushing's disease (CD). In case of recurrence, pituitary irradiation or adrenalectomy are usually performed; however, the morbidity due to these procedures is n...
W B Hanley
W B Hanley
Phenylketonuria (PKU) was first described over 70 years ago, treatment was developed 50 years ago and universal newborn PKU screening was introduced 40 years ago. Phenylalanine-restricted dietary treatment has prevented mental retardation i...
Jeff Mp Holly,Emily J Foulstone,Claire M Perks
Jeff Mp Holly
Recent evidence from epidemiology indicates that inter-individual variations in the growth hormone (GH)/IGF-I pathway affect the risk of individuals developing common epithelial cancers. This is supported by associations between normal comm...
Sebastian M Schmid,Manfred Hallschmid,Bernd Schultes
Sebastian M Schmid
Pamela U Freda
Pamela U Freda
Despite traditional, multimodality therapy that consisted of surgery, radiotherapy and medical therapies, many patients with acromegaly could not be adequately treated. Pegvisomant is a novel growth hormone receptor antagonist that became a...
Rapid-acting insulin glulisine: a new tool for postprandial glucose control [0.03%]
餐后血糖控制的新工具：门冬胰岛素注射液
George Dailey
George Dailey
Insulin glulisine (Apidra®, Sanofi-Aventis) is a novel, rapid-acting insulin analog that replicates normal mealtime insulin secretion more closely than regular human insulin. Compared with regular human insulin, glulisine has a more rapid ...