Fixed-dose combination of ertugliflozin and metformin hydrochloride for the treatment of type 2 diabetes [0.03%]
恩格列净和盐酸二甲双胍固定剂量复方治疗2型糖尿病
Juan Pablo Frias
Juan Pablo Frias
Combining antihyperglycemic agents in order to rapidly and safely achieve the best possible glycemic control is the standard of care today for the management of type 2 diabetes. Agents should ideally have mechanisms of actions that are comp...
Philippe Chanson,Magaly Vialon,Philippe Caron
Philippe Chanson
Introduction: As pregnancy is rare in women with acromegaly, only case reports and few series have been published. Areas covered: All c...
Endoscopic management of weight regain following Roux-en-Y gastric bypass [0.03%]
再次胃旁路手术后的体重增加的内窥镜管理
Diogo Turiani Hourneaux De Moura,Christopher C Thompson
Diogo Turiani Hourneaux De Moura
Introduction: With the cumulative increase in the number of patients undergoing bariatric surgery, postoperative weight regain has become a considerable challenge. Mechanisms for weight regain are not fully understood and...
Ruchi Gaba,Paras Mehta,Ashok Balasubramanyam
Ruchi Gaba
Introduction: Patients presenting with diabetic ketoacidosis (DKA) who lack the classic phenotype of autoimmune type 1 diabetes have become increasingly identified in recent decades. This has led to the recognition of het...
Management of hyponatremia: causes, clinical aspects, differential diagnosis and treatment [0.03%]
低钠血症的管理：病因、临床表现、鉴别诊断和治疗
Alessandro Peri
Alessandro Peri
Introduction: Hyponatremia is the most frequent electrolyte disorder in hospitalised patients. Acute and severe hyponatremia may be a life-threatening situation. However, also mild and chronic hyponatremia may negatively ...
Long-term effects on growth, development, and metabolism of ALL treatment in childhood [0.03%]
儿童急性淋巴细胞白血病治疗的远期效果对其生长、发育和代谢的影响
Patrizia Bruzzi,Elena Bigi,Barbara Predieri et al.
Patrizia Bruzzi et al.
Introduction: One aim of the long-term care in survivors from acute lymphoblastic leukemia (ALL) during childhood is to avoid or limit complications caused by aggressive therapeutic strategies. ...
Coralys Abreu,Gerardo Guinto,Moisés Mercado
Coralys Abreu
Introduction: Acromegaly requires a multimodal treatment approach that includes surgery by an expert pituitary neurosurgeon, pharmacological treatment with one or more of the available drugs and radiation therapy. These t...
Cardiometabolic risks in PCOS: a review of the current state of knowledge [0.03%]
多囊卵巢综合征的 cardio-metabolic风险：目前知识状态综述
N S Kakoly,L J Moran,H J Teede et al.
N S Kakoly et al.
Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting up to 18% women of reproductive age. It is associated with a range of metabolic, reproductive, and psychological features. Current ev...
Diet and prevention of type 2 diabetes mellitus: beyond weight loss and exercise [0.03%]
饮食与2型糖尿病的预防：减肥和锻炼之外的因素
Orsolya M Palacios,Melvyn Kramer,Kevin C Maki
Orsolya M Palacios
Introduction: Insulin resistance (IR) and pancreatic beta-cell dysfunction are core pathophysiologic features of type 2 diabetes mellitus (T2DM). Select lifestyle and pharmacologic interventions, including weight loss, ph...