Understanding the relationship between heart failure and osteoporosis-related fractures [0.03%]
心力衰竭与骨质疏松性骨折的关系分析
Kristin J Lyons,Sumit R Majumdar
Kristin J Lyons
Luciano Colangelo,Federica Biamonte,Jessica Pepe et al.
Luciano Colangelo et al.
Introduction: The term secondary osteoporosis (SO) identifies a reduction of bone mass related to a well-established disease or pharmacological agent. The identification of the underlying disease often represents a challe...
Pediatric hormonal disturbances after hematopoietic stem cell transplantation [0.03%]
造血干细胞移植后儿科激素紊乱
Zeynep Siklar,Merih Berberoglu
Zeynep Siklar
Hematopoietic stem cell transplantation (HSCT) is the treatment of choice for various malignant and nonmalignant diseases. Improvement of HSCT in children has resulted in many long-term survivors with substantial long-term morbidities. Endo...
Ethnic-specific polycystic ovary syndrome: epidemiology, significance and implications [0.03%]
民族特异性的多囊卵巢综合征：流行病学、意义及影响
Chandrika N Wijeyaratne,S A Dilini Udayangani,Adam H Balen
Chandrika N Wijeyaratne
Being the most common endocrinopathy of young women, polycystic ovary syndrome has much variation in its clinical expression based on ancestry. Ethnic differences of the phenotype are closely linked to its complex pathophysiology. This pape...
Kohkichi Morimoto,Hiroshi Itoh,Mitsuhiro Watanabe
Kohkichi Morimoto
Bile acids (BAs) are not only facilitators participating in the absorption of dietary lipids and soluble vitamins, but are also important signaling molecules exerting versatile biophysiological effects. Three major signaling pathways, inclu...
Roderick Clifton-Bligh
Roderick Clifton-Bligh
Pheochromocytomas or functioning paragangliomas can present in a dramatic manner with headache, palpitations and sometimes shock, but many occur with few symptoms despite at times markedly elevated catecholamine levels. Hypertension is not ...
Is classical pseudoxanthoma elasticum a consequence of hepatic 'intoxication' due to ABCC6 substrate accumulation in the liver? [0.03%]
经典的假黄瘤病是否是由于ABCC6底物在肝脏中积累导致的肝"中毒"所致？
Mie Rostved Rasmussen,Mette Sommerlund,Søren Kragh Moestrup
Mie Rostved Rasmussen
Pseudoxanthoma elasticum (PXE) is a serious genetic disorder with ectopic mineralization affecting the skin, the eye and the cardiovascular system. The disease is predominantly caused by mutations in the transmembrane ABC protein ABCC6, a p...
Clinical overview of linagliptin, a dipeptidyl peptidase-4 inhibitor, in patients with Type 2 diabetes mellitus [0.03%]
利格列汀治疗2型糖尿病患者的临床概况——一种二肽基肽酶-Ⅳ抑制剂
Thomas Forst,Andreas Pfützner
Thomas Forst
Linagliptin is a pharmacologically unique, orally active, once-daily dipeptidyl peptidase-4 inhibitor indicated for the treatment of hyperglycemia in patients with Type 2 diabetes mellitus. Compared with other dipeptidyl peptidase-4 inhibit...
Kausik Umanath,Robert Niecestro,Julia B Lewis et al.
Kausik Umanath et al.
Ferric citrate (KRX-0502; Keryx Biopharmaceuticals, Inc., NY, USA) is a novel phosphate-binding agent presently in Phase III clinical development. Ferric citrate dissociates in the bowel lumen releasing the ferric ion to precipitate with di...
Chiara Cerini,Chiara Mameli,Gian Vincenzo Zuccotti
Chiara Cerini